Immune System News and Research

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Forecasting COVID-19 surges based on SARS-CoV-2 mutation surveillance

Researchers predicted surges in SARS-CoV-2 infections based on alterations in SARS-CoV-2 mutations.

13 Sep 2022

New long-term opioid use associated with a heightened risk of death, study finds

New long term use of opioids to quell pain after lung cancer surgery is linked to a 40% heightened risk of death from any cause within the next 2 years, finds research published online in the journal Regional Anesthesia & Pain Medicine.

13 Sep 2022

LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Zika virus has a trick up its sleeve. Once inside the body, the virus likes to make a bee line for dendritic cells, the cells we rely on to launch an effective immune response.

12 Sep 2022

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

The use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer, accelerated their metastatic bone growth, likely because the drugs depleted the mice's intestinal flora and weakened their immune response, according to a new study by researchers at Emory University in Atlanta.

12 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

Researchers investigated the prevalence of HIV, and other recent sexually transmitted infection diagnoses among persons with monkeypox.

12 Sep 2022

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

12 Sep 2022

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

New research has suggested that recommended vaccinia virus (VACV)-based vaccines will mount a robust immune response against the monkeypox virus observed in the current outbreak (MPXV-2022).

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders - think viruses, bacteria, and parasites - but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

A new monkeypox vaccine is needed to prevent global transmission

In a recent study published in the journal Vaccines, scientists reviewed all relevant literature to find the available vaccines and therapeutics to prevent MPV.

11 Sep 2022

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

Every day we inhale thousands of potentially pathogenic fungal spores, but our immune system simply eliminates them.

9 Sep 2022

New research project investigates molecular mechanisms underlying NeuroCOVID

Infections with the coronavirus SARS-CoV-2 can trigger both temporary and long-term neurological and neuropsychiatric symptoms, severely impacting patients and the wider society.

9 Sep 2022

Duke researchers identify chlamydia’s stealthy cloaking device

Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination inside human cells by use of a cloaking device. But Duke University researchers have grasped the hem of that invisibility cloak and now hope they can pull it apart.

9 Sep 2022

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Potential HIV vaccine component leads to strong protection in primates

To block infection from HIV, a successful vaccine will require a combination of ingredients, including at least three antibody targets and a substance that boosts immune responses.

9 Sep 2022

Wayne State receives $11.3 million NIH award to tackle health problems caused by VOCs

Wayne State University has received a five-year, approximately $11.3 million award from the National Institute of Environmental Health Sciences of the National Institutes of Health to create a new Superfund Research Program, the "Center for Leadership in Environmental Awareness and Research (CLEAR)."

9 Sep 2022

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Over the past two years, scientists have studied the SARS-CoV-2 virus in great detail, laying the foundation for developing COVID-19 vaccines and antiviral treatments.

9 Sep 2022

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

Why did my child get cancer? Clinicians have longed for a way to help answer this question. Doctors knew Hodgkin lymphoma sometimes occurs in families, but why this happens has been a mystery. Scientists at St. Jude Children's Research Hospital have now helped solve it.

9 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Immune System News and Research

Forecasting COVID-19 surges based on SARS-CoV-2 mutation surveillance

New long-term opioid use associated with a heightened risk of death, study finds

LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Antibiotics accelerate metastatic bone growth in mice with melanoma by depleting intestinal flora

Research could lead to a new therapeutic option for patients with bladder cancer

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

A new monkeypox vaccine is needed to prevent global transmission

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

New research project investigates molecular mechanisms underlying NeuroCOVID

Duke researchers identify chlamydia’s stealthy cloaking device

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Potential HIV vaccine component leads to strong protection in primates

Wayne State receives $11.3 million NIH award to tackle health problems caused by VOCs

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

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