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Understanding biomolecular frustration could help design better drugs

Knowing precisely where proteins are frustrated could go a long way toward making better drugs.

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Using computational methods, a team of researchers identified three compounds in traditional Chinese medicine that could be used against SARS-CoV-2.

23 Nov 2020

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains information for the production of 27 proteins.

23 Nov 2020

Researchers prepare synthetic protocells that pump up blood vessels

An international team comprising researchers from the University of Bristol, and Hunan and Central South Universities in China, have prepared biocompatible protocells that generate nitric oxide gas – a known reagent for blood vessel dilation - that when placed inside blood vessels expand the biological tissue.

23 Nov 2020

Discovery reveals a fundamental way cells interpret signals from the environment

A basic science discovery by researchers at the Johns Hopkins Bloomberg School of Public Health reveals a fundamental way cells interpret signals from their environment and may eventually pave the way for potential new therapies.

20 Nov 2020

New method of repairing damage to optic nerve offers hope for people with glaucoma-related sight loss

Fight for Sight funded researchers have successfully demonstrated a new method of repairing damage to the optic nerve in the lab for the first time, in new research that hopes to restore vision to those who’ve lost it as a result of glaucoma and other conditions.

20 Nov 2020

Vibrational motions of spike proteins correlate with infectivity and lethality of coronaviruses

When someone struggles to open a lock with a key that doesn't quite seem to work, sometimes jiggling the key a bit will help.

19 Nov 2020

New druggable target for heart failure in neonates and infants identified

Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment.

19 Nov 2020

Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

18 Nov 2020

Altered gut microbiota increases production of molecules that may contribute to type 2 diabetes

It is the bacterial changes in the gut that increase the levels of imidazole propionate, the molecule that makes the body's cells resistant to insulin in type 2 diabetes. This result emerges from a European study, MetaCardis.

18 Nov 2020

Brain protein plays a major role in the development and growth of pancreatic cancer

Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer.

18 Nov 2020

Raman microscopy-based approach uses gold nanoparticles for visualizing small-molecule drugs

Successful drug development has a significant impact on people's quality of life worldwide. Being able to track how molecules get into target cells, and observing what they do when they are inside, is key to identifying the best candidates.

18 Nov 2020

Bioelectronic rapid test for COVID-19

A recent study presents a bioelectronic sensor platform to detect protein at the single-molecule level that is simple, rapid, and robust enough for widespread POC (point-of-care) or bedside application.

18 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Scientists uncover new method to produce compounds with anti-cancer properties

In the past decades, cancer has surpassed many other diseases to become the current second leading cause of death globally, with one in six people dying from it.

17 Nov 2020

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Study: Cannabidiol molecule contains more potent antioxidants

Nowadays, cannabidiol is a star component, not only in the world of cosmetics, but also in pharmaceutics and nutrition due to its antioxidant properties and its therapeutical potential.

17 Nov 2020

Molecule News and Research

Understanding biomolecular frustration could help design better drugs

SARS-CoV-2's spike protein mutations have slowed, study finds

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

Researchers prepare synthetic protocells that pump up blood vessels

Discovery reveals a fundamental way cells interpret signals from the environment

New method of repairing damage to optic nerve offers hope for people with glaucoma-related sight loss

Vibrational motions of spike proteins correlate with infectivity and lethality of coronaviruses

New druggable target for heart failure in neonates and infants identified

Alzheimer's study shows tau protein changes according to dementia stage

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

Altered gut microbiota increases production of molecules that may contribute to type 2 diabetes

Brain protein plays a major role in the development and growth of pancreatic cancer

Raman microscopy-based approach uses gold nanoparticles for visualizing small-molecule drugs

Bioelectronic rapid test for COVID-19

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Scientists uncover new method to produce compounds with anti-cancer properties

Hydrogen therapy may help severely ill COVID-19 patients

Study: Cannabidiol molecule contains more potent antioxidants

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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