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Chemical genetics uncovers promising anti-COVID compounds

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.

25 Sep 2024

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how molecular glue triggers degradation of PHGDH by enhancing the interaction between DDB1 and PHGDH.

25 Sep 2024

Combining treatments to boost tumor response in lung cancer

Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.

25 Sep 2024

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke.

25 Sep 2024

The potential to optimize laboratory testing and operations with automation and AI

In this interview, NewsMedical speaks with Cerba's Coen Staplers about the benefits of lab automation, including the integration of AI technologies.

From Cerba Research 25 Sep 2024

New approach to B-ALL treatment reduces side effects and enhances survival

Clinical trial results from St. Jude Children's Research Hospital demonstrate benefits to using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL).

24 Sep 2024

Music therapy improves sleep and comfort in preterm infants

Daily music interventions significantly improved comfort and sleep transitions in preterm infants without affecting physiological stability. This study highlights the potential of non-pharmacological music therapy in neonatal care.

24 Sep 2024

Innovative ALS study receives $22 million grant for experimental drug

Mayo Clinic in Florida has received a grant from the National Institute of Neurological Disorders and Stroke (NIDS) to begin an innovative study that will provide hundreds of patients with amyotrophic lateral sclerosis (ALS) access to the experimental drug ibudilast over six months.

24 Sep 2024

Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal cord.

24 Sep 2024

Brain connectivity changes after psilocybin treatment in body dysmorphic disorder patients

Body dysmorphic disorder (BDD) is a debilitating mental illness characterized by an obsessive preoccupation with perceived flaws in one's physical appearance.

24 Sep 2024

Incidence and risk factors of an invasive fungal lung infection among COVID-19 patients

Study reveals 0.4%-2.7% incidence of COVID-19-associated pulmonary aspergillosis in severe patients, highlighting significant mortality risks and risk factors.

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

News-Medical announces partnership with World Orphan Drug Congress

Engage with over 2000 attendees at the World Orphan Drug Congress Europe, focusing on gene therapy and strategies for rare disease treatment advancements.

From World Orphan Drug Congress 23 Sep 2024

Enhanced TnpB protein offers new possibilities for gene editing

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissor" but is much smaller and thus easier to transport into cells.

23 Sep 2024

Broken String Biosciences appoints Laurence Reid and Brad Crutchfield to its Board of Directors

Broken String Biosciences enhances its leadership team with Laurence Reid and Brad Crutchfield, aiming to revolutionize cell and gene therapy development.

From Broken String Biosciences 23 Sep 2024

Chemotherapy linked to increased cardiovascular risks in older cancer survivors

A study based on clinical trial data found higher risks of stroke, heart attack, and hospital admission for heart failure in older cancer survivors.

23 Sep 2024

Triptans better at relieving migraine pain than recently marketed and more expensive drugs

A meta-analysis reveals triptans as the most effective acute migraine treatments, highlighting the need for their inclusion in the WHO Essential Medicines List.

23 Sep 2024

MaxCyte signs strategic platform license with Kamau Therapeutics to accelerate the development of cell therapies for genetic diseases

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and innovative bioprocessing applications, and Kamau Therapeutics, a clinical-stage stem cell therapy gene correction company, today announced they are entering into a strategic platform license (SPL) agreement.

From MaxCyte, Inc. 23 Sep 2024

Psilocybin shows promise for treating depression and improving well-being

A direct comparison between the experimental psychedelic drug psilocybin and a standard SSRI antidepressant shows similar improvement of depressive symptoms, but that psilocybin offers additional longer-term benefits.

22 Sep 2024

Therapy News and Research

Chemical genetics uncovers promising anti-COVID compounds

Optimized nanoadjuvants enhance in situ tumor vaccine for ovarian cancer

Combining treatments to boost tumor response in lung cancer

Heme oxygenase 1 and ferroptosis in Kupffer cells linked to heat stroke injury

The potential to optimize laboratory testing and operations with automation and AI

New approach to B-ALL treatment reduces side effects and enhances survival

Music therapy improves sleep and comfort in preterm infants

Innovative ALS study receives $22 million grant for experimental drug

Innovative HiTIP-seq method advances epigenetic research in pediatric brain tumors

Brain connectivity changes after psilocybin treatment in body dysmorphic disorder patients

Incidence and risk factors of an invasive fungal lung infection among COVID-19 patients

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

New drug combo shows promise for deeper remission in chronic leukemia

News-Medical announces partnership with World Orphan Drug Congress

Enhanced TnpB protein offers new possibilities for gene editing

Broken String Biosciences appoints Laurence Reid and Brad Crutchfield to its Board of Directors

Chemotherapy linked to increased cardiovascular risks in older cancer survivors

Triptans better at relieving migraine pain than recently marketed and more expensive drugs

MaxCyte signs strategic platform license with Kamau Therapeutics to accelerate the development of cell therapies for genetic diseases

Psilocybin shows promise for treating depression and improving well-being

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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