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Japanese study sheds light on genetic counseling for AATRv amyloidosis

Early detection and treatment of hereditary transthyretin-related amyloidosis via genetic counseling are crucial.

13 Jun 2024

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

13 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

Alzheimer's disease is the world's most common neurodegenerative disease, affecting more than 50 million people globally.

12 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals - a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

Many young adults who began vaping as teens can’t shake the habit

G Kumar’s vaping addiction peaked in college at the University of Colorado, when flavored, disposable vapes were taking off.

12 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Mechanistic connections between vascular health and dementia risk in older adults

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Peripheral vascular dysfunction and the aging brain."

12 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Rising syphilis cases highlight gaps in public knowledge on symptoms and treatment

Syphilis cases are on the rise around the globe, but many Americans don't know the symptoms.

12 Jun 2024

The unregulated sale of Amanita muscaria mushrooms needs a public health response

The legal status, safety, and availability of Amanita muscaria.

12 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024

Next-generation soft robots with sensory e-skin enhance patient care

University of North Carolina at Chapel Hill scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time, according to the paper, "Skin-Inspired, Sensory Robots for Electronic Implants," in Nature Communications.

11 Jun 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Microgravity and galactic radiation: Dual threats to astronaut kidney health

The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardize any mission to Mars, according to a new study led by researchers from UCL.

11 Jun 2024

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Systematic reviews of medical literature between 2020 to 2024 show bariatric surgery, also known as metabolic or weight-loss surgery, produces the greatest and most sustained weight loss compared to GLP-1 receptor agonists and lifestyle interventions.

11 Jun 2024

Study uncovers two types of dysbiosis in cystic fibrosis

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis.

11 Jun 2024

Drugs News and Research

Japanese study sheds light on genetic counseling for AATRv amyloidosis

Study uncovers why targeted therapy fails in some non-small cell lung cancer patients

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Changing antibiotic delivery method improves sepsis outcomes globally

Many young adults who began vaping as teens can’t shake the habit

Synthetic cell mimics immune response via symmetry breaking

Mechanistic connections between vascular health and dementia risk in older adults

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Rising syphilis cases highlight gaps in public knowledge on symptoms and treatment

The unregulated sale of Amanita muscaria mushrooms needs a public health response

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Next-generation soft robots with sensory e-skin enhance patient care

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

Microgravity and galactic radiation: Dual threats to astronaut kidney health

Metabolic surgery proven most effective for sustained weight loss over GLP-1 drugs and lifestyle interventions

Study uncovers two types of dysbiosis in cystic fibrosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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