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Cracking the code of adolecent drug use

A University of Sydney researcher has won a grant to study how exposure to drugs during adolescence affects the brain and behaviour.

23 Oct 2008

Researchers downplay value of mandatory universal nasal screening of patients for MRSA

Three Virginia Commonwealth University epidemiologists are downplaying the value of mandatory universal nasal screening of patients for MRSA, arguing that proven, hospital-wide infection control practices can prevent more of the potentially fatal infections.

23 Oct 2008

Ministers urged to rethink rather than repackage $2 billion global response to infectious diseases

As the first globally co-ordinated plan for the planet's gravest health threats is hatched by government ministers from around the world this weekend, a new report sets out a 10-point plan for this new, globalised approach to infectious diseases such as avian flu.

23 Oct 2008

Nymox nears completion of benign prostatic hyperplasia drug trial

Nymox Pharmaceutical Corporation has announced that the Company's latest multi-center U.S. study of NX-1207, its investigational drug for the treatment of benign prostatic hyperplasia (BPH), is nearing completion.

23 Oct 2008

New obesity drug Tesofensine may have huge potential

According to trials, a new obesity drug, Tesofensine, which may be launched on the world market in a few years, can produce weight loss twice that of currently approved obesity drugs. The Danish company Neurosearch and a number of researchers at the Faculty of Life Sciences at University of Copenhagen are behind the promising findings.

23 Oct 2008

Could brain abnormality predict drug addiction?

Scientists at The University of Nottingham are to use MRI technology to discover whether abnormalities in the decision-making part of the brain could make some people more likely to become addicted to drugs.

22 Oct 2008

CytoDyn files new IND for Cytolin

CytoDyn, Inc. has filed a new IND for a study to reconfirm dose ranging and to "prove the principle" with a randomized, double-blind placebo controlled study of Cytolin, the Company's first-in-class drug for treating HIV/AIDS. This comes 13 years after the first IND was issued for the drug.

22 Oct 2008

Gene study sheds new light on lung cancer

A multi-institution team, funded by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH), today reported results of the largest effort to date to chart the genetic changes involved in the most common form of lung cancer, lung adenocarcinoma. The findings should help pave the way for more individualized approaches for detecting and treating the nation's leading cause of cancer deaths.

22 Oct 2008

Trius Therapeutics awarded $28 million to develop novel drugs targeting bacterial DNA Gyrase and Topoisomerase IV

Trius Therapeutics, Inc., today announced the award of a $28 million contract from the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, for the development of novel antibiotics directed against multiple Gram-negative bacterial pathogens.

22 Oct 2008

Researchers identify novel type of antibody that potently inhibits HIV infection

A small antibody fragment that is highly effective in neutralizing the human immunodeficiency virus (HIV) by preventing the virus from entering cells has been identified by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

21 Oct 2008

Fatty acids may be the culprit in Alzheimer's

According to new research from the U.S. controlling the level of a fatty acid in the brain could help treat Alzheimer's disease (AD).

21 Oct 2008

Link between erectile dysfunction and heart attacks

A link between erectile dysfunction and heart attacks will be made by Professor Mike Kirby at the University of Hertfordshire Health and Human Sciences Research Institute Showcase today.

20 Oct 2008

Contact lenses are home to pathogenic amoebae

Contact lenses increase the risk of infection with pathogenic protozoa that can cause blindness. New research, published in the November issue of the Journal of Medical Microbiology, shows that a high percentage of contact lens cases in Tenerife are contaminated with Acanthamoeba that cannot be killed by normal contact lens solution.

20 Oct 2008

Getting to grips with the complexity of disease proteins

Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs.

20 Oct 2008

Johns Hopkins researchers detect sweet cacophany while listening to cellular cross-talk

Johns Hopkins scientists were dubious in the early 1980s when they stumbled on small sugar molecules lurking in the centers of cells; not only were they not supposed to be there, but they certainly weren't supposed to be repeatedly attaching to and detaching from proteins, effectively switching them on and off.

20 Oct 2008

New hope for a better treatment for childhood cancer

Children who are diagnosed with cancer could benefit from better diagnosis and treatment in the future thanks to a new research project involving clinicians and scientists at The University of Nottingham.

20 Oct 2008

New atlas maps geographical pattern of mortality in Great Britain

Researchers from the Universities of Bristol and Sheffield have created an 'atlas of death' which charts the geographical pattern of mortality in Great Britain. The full-colour atlas shows the wide variation in death rates from a variety of different causes, from heart attacks and cancer to suicide and murder, for over 1,000 neighbourhoods.

20 Oct 2008

FDA approves new labeling for psoriasis drug Raptiva

The U.S. Food and Drug Administration today announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab). The labeling changes are based on the FDA's post-market surveillance.

19 Oct 2008

Genes that control cell death may play role in age-related hearing loss

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis - a journal devoted to the topic of cell suicide, or programmed cell death.

19 Oct 2008

Waste from gut bacteria helps host control weight

A single molecule in the intestinal wall, activated by the waste products from gut bacteria, plays a large role in controlling whether the host animals are lean or fatty, a research team, including scientists from UT Southwestern Medical Center, has found in a mouse study.

19 Oct 2008