Adolescents News and Research

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Polysubstance-involved opioid overdoses found to be prevalent among youth

Most research suggests that opioid overdoses involving multiple substances in the United States typically occur among people ages 25-54.

26 Aug 2025

HIIT increases aerobic capacity even when BMI stays the same

HIIT effectively improves health outcomes in obese teens, enhancing fitness and metabolic health while reducing body fat and improving cholesterol profiles.

26 Aug 2025

Mind wandering may hold key to better ADHD diagnosis in adults

Only a few decades ago, it was believed that ADHD was something one outgrew during adolescence. However, about half of those diagnosed at a young age carry it into adulthood.

25 Aug 2025

Inconsistent state laws undermine sexual education across the United States

While the majority of states require public school students to take at least one sexual education course, a patchwork of state-level provisions that mandate inaccurate, outdated, or politically motivated curricula may inhibit students from receiving essential information for their sexual health and well-being.

22 Aug 2025

How older people are reaping brain benefits from new tech

It started with a high school typing course. Wanda Woods enrolled because her father advised that typing proficiency would lead to jobs. Sure enough, the federal Environmental Protection Agency hired her as an after-school worker while she was still a junior.

21 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Less than half of adolescents with major depression receive mental health care

Fewer than half of all adolescents with major depressive episode (MDE) received mental health care in the US in 2022, with the odds of specialist treatment being even lower among marginalized groups, according to a new study published this week in the open-access journal PLOS Mental Health by Su Chen Tan and colleagues at University of Tennessee, USA.

20 Aug 2025

Sleep problems in teenagers predict self-harm risk over time

Self-harm in young people is a major public health concern, rates are rising, and the adolescent years presents a critical period of intervention.

20 Aug 2025

School connectedness protects adolescents from depression linked to bullying

School connectedness buffers against depression symptoms associated with being a victim of peer bullying in adolescence, according to a study published in BMC Public Health.

19 Aug 2025

Ultra-processed foods undermine diet quality in Mediterranean youth, study shows

A large study across five Mediterranean countries found that children and adolescents who consumed more unhealthy ultra-processed foods (UPFs) had significantly poorer diet quality. Daily UPF intake was especially linked to lower adherence to the Mediterranean diet and reduced compliance with dietary guidelines.

18 Aug 2025

Prenatal exposure to common insecticide linked to brain changes and poor motor skills in children

A new study reports evidence of a link between prenatal exposure to the widely used insecticide chlorpyrifos (CPF) and structural abnormalities in the brain and poorer motor function in New York City children and adolescents.

18 Aug 2025

Over-the-counter oral birth control pill improves access to contraception

Two years ago, the Food and Drug Administration approved the sale of an over-the-counter birth control pill for the first time in the United States without a prescription.

18 Aug 2025

Highly sensitive individuals more prone to mental health challenges

The meta-analysis of 33 studies, the first of its kind, looked at the relationship between sensitivity and common mental health problems such as depression and anxiety.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

18 Aug 2025

Detecting diabetes risk by analyzing household data

New research to be presented at the 2025 Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (September 15-19, 2025) shows that early detection of individuals at risk for diabetes is possible by analyzing the electronic records of people living within the same household for risk factors. The study is led by Dr Tainayah Thomas, Stanford University, Palo Alto, CA, USA, and colleagues.

18 Aug 2025

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

Adolescents who undergo bariatric surgery face a higher risk of weight regain, which can undermine treatment success and long-term health, if they have elevated blood levels of per- and polyfluoroalkyl substances (PFAS) prior to the procedure, according to new USC research.

14 Aug 2025

Pandemic left measurable changes in teen brains, hormones, and immunity

Adolescents assessed after COVID-19 lockdowns showed lower daily cortisol, higher inflammation, and reduced prefrontal cortex activity compared to matched pre-pandemic peers, suggesting widespread stress-related biological changes. These alterations mirror patterns seen after prolonged early-life stress, raising concerns about long-term health risks.

13 Aug 2025

Understanding opioid safety and overdose prevention for older adults

With increasing age, older adults are more likely to encounter health conditions and injuries that require opioid therapy for pain relief.

13 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025