Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

VIA Pharmaceuticals, Inc. has announced the results of two Phase 2 studies of its lead drug, VIA-2291.

10 Nov 2008

Heart attack prevention within three months after hospitalization significantly averted future attacks

Despite substantial progress in the diagnosis and treatment of heart attack patients, prevention of recurrent heart attacks continues to be a major clinical challenge.

10 Nov 2008

Five key proteins form new, early-warning blood test before heart attack strikes

A team of Johns Hopkins biochemists has identified a mixed bag of five key proteins out of thousands secreted into blood draining from the heart's blood vessels that may together or in certain quantities form the basis of a far more accurate early warning test than currently in use of impending heart attack in people with severely reduced blood flow, or ischemia.

10 Nov 2008

Rising triglyceride levels may be behind rising rates of obesity

A new 30-year analysis of the National Health and Nutrition Examination Survey (NHANES) database conducted by the National Lipid Association (NLA) indicates that while Americans are doing a better job of managing LDL or "bad" cholesterol, the percentage of adults with high triglycerides, a blood fat linked to heart disease, has doubled, leaving many people at risk for potentially life-threatening events such as heart attack or stroke.

10 Nov 2008

Low-dose aspirin does not appear to reduce risk of CV events in patients with diabetes

Low-dose aspirin as primary prevention did not appear to significantly reduce the risk of a combined end point of coronary, cerebrovascular and peripheral vascular events in patients with type 2 diabetes, according to a new study in JAMA.

10 Nov 2008

Hispanics less likely to have repeat revascularizations 1 year after angioplasty

Hispanic patients were 57 percent less likely than Caucasian patients to undergo coronary artery bypass surgery (CABG) one year after successful angioplasty, a type of percutaneous coronary intervention (PCI) to open blockages in the coronary arteries.

10 Nov 2008

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

New data from the JUPITER study demonstrated that Crestor (rosuvastatin calcium) 20 mg significantly reduced major cardiovascular (CV) events (defined in this study as the combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from CV causes) by a dramatic 44% compared to placebo (p<0.001) among men and women with elevated hsCRP but low to normal cholesterol levels.

10 Nov 2008

For African Americans with hypertensive nephrosclerosis, end stage renal disease risks exceed risk of death from heart disease

For most patients with chronic kidney disease (CKD), the risk of experiencing a cardiovascular related death is greater than the risk of progressing to end-stage renal disease (ESRD).

7 Nov 2008

ERSD, heart disease and African-Americans with hypertensive nephrosclerosis

For most patients with chronic kidney disease (CKD), the risk of experiencing a cardiovascular related death is greater than the risk of progressing to end-stage renal disease (ESRD).

7 Nov 2008

Risk of sudden cardiac death greater in 30 days following heart attack

The risk of sudden cardiac death following a heart attack has declined significantly in the past 30 years, although patients appear to be at elevated risk for sudden cardiac death for the first month after having a heart attack, after which time their risk decreases unless they develop heart failure, according to a study in the November 5 issue of JAMA.

5 Nov 2008

Risk of sudden cardiac death highest early after attack

People who survive a heart attack face the greatest risk of dying from sudden cardiac death (SCD) during the first month after leaving the hospital, according to a long-term community study by Mayo Clinic researchers of nearly 3,000 heart attack survivors.

5 Nov 2008

Experts available to comment on risk of sudden cardiac death in 30 days following a heart attack

A new study in the November 5th 2008 issue of JAMA finds that during the first month after a heart attack, patients may have an increased risk for sudden cardiac death.

5 Nov 2008

Heart attack survivors at highest risk of dying in the month after leaving hospital

According to researchers in the U.S. survivors of heart attacks face the greatest risk of dying from sudden cardiac death during the first month after leaving the hospital.

5 Nov 2008

Post-traumatic stress disorder symptoms linked to increased risk of death after heart events

Individuals who receive implantable cardiac defibrillators after a sudden heart event appear more likely to die within five years if they experience symptoms of post-traumatic stress disorder, regardless of the severity of their disease, according to a report in the November issue of Archives of General Psychiatry.

4 Nov 2008

Novel scaffold to fix broken hearts

Broken hearts could one day be mended using a novel scaffold developed by MIT researchers and colleagues.

2 Nov 2008

Harvard study looks at quality of hospitals across the United States

The quality of hospitals across the United States is inconsistent. To address this issue, the federal government and private organizations have begun to publicly report data, such as how well hospitals treat certain conditions.

31 Oct 2008

GlaxoSmithKline believes there is no liver safety issue with Avandia (rosiglitazone maleate)

GlaxoSmithKline today issued the following response to a petition filed by Public Citizen to the U.S. Food and Drug Administration (FDA) on Avandia (rosiglitazone maleate), a highly effective therapy for treating type 2 diabetes when used in the appropriate patient population.

31 Oct 2008

Adjusting the clocks to summer time affects risk of heart attack

Adjusting the clocks to summer time on the last Sunday in March increases the risk of myocardial infarction in the following week. In return, putting the clocks back in the autumn reduces the risk, albeit to a lesser extent. This according to a new Swedish study published in the prestigious New England Journal of Medicine.

30 Oct 2008

Stem cell therapies for heart disease - one step closer

New research from the University of Bristol brings stem cell therapies for heart disease one step closer. The findings reveal that our bodies' ability to respond to an internal 'mayday' signal may hold the key to success for long-awaited regenerative medicine.

30 Oct 2008

Tiny hearts may have big problems with complementary medicine

Giving supplement such as herbs, vitamins, and other natural health products to children taking Warfarin for congenital heart defects could increase their risk of clots, bleeding, and other complications, nurse practitioner Mary Bauman and Dr. Patti Massicotte told the 2008 Canadian Cardiovascular Congress, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.

28 Oct 2008

Heart Attack (Myocardial Infarction) News and Research

Further Reading

VIA Pharmaceuticals announces results of phase 2 trials of VIA-2291 in cardiovascular disease

Heart attack prevention within three months after hospitalization significantly averted future attacks

Five key proteins form new, early-warning blood test before heart attack strikes

Rising triglyceride levels may be behind rising rates of obesity

Low-dose aspirin does not appear to reduce risk of CV events in patients with diabetes

Hispanics less likely to have repeat revascularizations 1 year after angioplasty

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

For African Americans with hypertensive nephrosclerosis, end stage renal disease risks exceed risk of death from heart disease

ERSD, heart disease and African-Americans with hypertensive nephrosclerosis

Risk of sudden cardiac death greater in 30 days following heart attack

Risk of sudden cardiac death highest early after attack

Experts available to comment on risk of sudden cardiac death in 30 days following a heart attack

Heart attack survivors at highest risk of dying in the month after leaving hospital

Post-traumatic stress disorder symptoms linked to increased risk of death after heart events

Novel scaffold to fix broken hearts

Harvard study looks at quality of hospitals across the United States

GlaxoSmithKline believes there is no liver safety issue with Avandia (rosiglitazone maleate)

Adjusting the clocks to summer time affects risk of heart attack

Stem cell therapies for heart disease - one step closer

Tiny hearts may have big problems with complementary medicine

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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