Hyperglycemia News and Research

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Hyperglycemia occurs when you have a higher than usual level of glucose in your blood. This can happen shortly after you have eaten a big meal and is not a problem if your glucose level returns to normal. Cells remove glucose from the blood in response toinsulin. If your pancreas doesn't make enough insulin, glucose can't enter the cells and remains in the blood. Blood glucose levels can also get too high if cells areunable to respond to insulin properly (insulinresistance). Without glucose, your cells are unable to make energy and can't function properly.

Researchers uncover novel therapeutic target for type 2 diabetes

Researchers from Kanazawa University and the National Center for Global Health and Medicine in Tokyo report, in Nature Communications, a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment.

6 Feb 2018

FDA approves new radioactive drug for treatment of rare digestive tract cancers

The U.S. Food and Drug Administration today approved Lutathera (lutetium Lu 177 dotatate) for the treatment of a type of cancer that affects the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

29 Jan 2018

Researchers identify potential enzyme as therapeutic target for type 2 diabetes

Abnormalities in glucose uptake by the liver (or hepatic glucose uptake; HGU) cause elevations in blood glucose levels following meals, a state that is known as postprandial hyperglycemia.

27 Jan 2018

Research opens door to development of new treatment for type 2 diabetes

The team lead by Sílvia Vilares Conde, from CEDOC-NOVA Medical School, in collaboration with the pharmaceutical company Galvani Bioelectronics, demonstrated through findings in rats that is possible to restore insulin sensitivity and glucose homeostasis, by modulating electrically the carotid sinus nerve, the sensitive nerve that connects the carotid body with the brain. The study is published in Diabetologia, the journal of the European Association for the Study of Diabetes.

15 Jan 2018

New research finds out how cinnamon may help fight against obesity

New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice--cinnamon--might be enlisted in the fight against obesity.

21 Nov 2017

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Sunovion Pharmaceuticals Inc. today announced post-hoc analysis results of a positive Phase 3 placebo-controlled clinical study, as well as interim data from a long-term open-label extension study evaluating Latuda (lurasidone HCI) in children and adolescents (10 to 17 years of age) with major depressive episodes associated with bipolar I disorder (bipolar depression).

28 Oct 2017

Key features that distinguish Brittle Type 1 Diabetes from stable T1D

Brittle Type 1 Diabetes (BT1D) is listed by the National Institutes of Health as a rare disease impacting some 4500 people in the USA. It is defined as a severe instability of blood glucose (BG) levels, whatever its cause, with frequent and unpredictable episodes of hypoglycemia (low) and or hyperglycemia (high sugars) that disrupts quality of life.

27 Oct 2017

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

A new study finds that patients with cancer, especially those aged 75 or older, are more likely to be admitted to the hospital – and less likely to be observed and released home – than patients without cancer.

25 Oct 2017

New study describes how gene-environment interaction leads to congenital heart defects

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental factors.

19 Oct 2017

Study identifies new biomarker for depression in diabetes

A study published in the current issue of Psychotherapy and Psychosomatic has identified a biomarker for depression in diabetes. Findings of epidemiological studies have shown an overall 2-fold increased prevalence of depression in patients with type 2 diabetes compared with the general population worldwide.

16 Oct 2017

Crown Bioscience announces availability of new translational models for obesity and diabetes in Europe

Crown Bioscience, a wholly-owned subsidiary of Crown Bioscience International and a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, announces the availability of their proprietary FATZO model in a European based laboratory.

12 Oct 2017

FDA approves FreeStyle Libre Flash Glucose Monitoring System for adult patients with diabetes

The U.S. Food and Drug Administration today approved the FreeStyle Libre Flash Glucose Monitoring System, the first continuous glucose monitoring system that can be used by adult patients to make diabetes treatment decisions without calibration using a blood sample from the fingertip.

27 Sep 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

FDA grants accelerated approval to new drug for treating relapsed follicular lymphoma

The U.S. Food and Drug Administration today granted accelerated approval to Aliqopa (copanlisib) for the treatment of adults with relapsed follicular lymphoma who have received at least two prior treatments known as systemic therapies.

14 Sep 2017

Novel technology holds promise for improving accuracy of type 1 diabetes tests

Researchers from the Johns Hopkins University School of Medicine, Stanford University and the University of Florida report the development of a novel antibody detection technology that holds promise for improving the accuracy of diagnostic tests for type 1 diabetes in young children and making populationwide screening practical.

13 Sep 2017

LORELEI trial: Treatment with alpha specific PI3K inhibitor reduces breast tumor size

Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI trial, presented at the ESMO 2017 Congress in Madrid.

8 Sep 2017

UA College of Medicine - Tucson selected for NIH initiative to advance critical emergency medicine research

The University of Arizona College of Medicine - Tucson is one of a team of six national institutions selected for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network, a new initiative of the National Institutes of Health to advance critical emergency medicine research.

26 Aug 2017

Hyperglycemia News and Research

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