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U.S. wastewater treatment fails to address rising organofluorine contamination

Municipal wastewater treatment plants remove less than 25% of extractable organofluorine, with fluorinated pharmaceuticals dominating contaminants and posing significant risks to U.S. drinking water quality.

7 Jan 2025

Health care is Newsom’s biggest unfinished project. Trump complicates that task.

Six years after he entered office vowing to be California's "health care governor," Democrat Gavin Newsom has steered tens of billions in public funding to safety net services for the state's neediest residents while engineering rules to make health care more accessible and affordable for all Californians.

7 Jan 2025

Glucarpidase shows promise in treating kidney toxicity from methotrexate

An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators at Mass General Brigham.

6 Jan 2025

Study reveals how fatty liver disease leads to liver cancer

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide.

2 Jan 2025

Research explores how carbon nanotubes help remove steroid hormones from water

Steroid hormones are among the most widespread aquatic micropollutants. They are harmful to human health, and they cause ecological imbalances in aquatic environments.

2 Jan 2025

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests.

2 Jan 2025

AMF at SLAS 2025: Precision microfluidics in San Diego

AMF is excited to participate in the SLAS 2025 International Conference & Exhibition, taking place from January 25-29, 2025 at the San Diego Convention Center. This renowned event will bring together professionals from across the life sciences, biotech, and automation industries to showcase the latest innovations and technologies.

From Advanced Microfluidics SA 24 Dec 2024

Linker histones found to regulate DNA transcription in apple cells

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's genetic code expresses itself.

23 Dec 2024

Annona squamosa extracts show promise in treating pain and arthritis

In Brazil, researchers have identified substances with analgesic, anti-inflammatory, anti-hyperalgesic (against persistent pain) and anti-arthritic activity in the leaves of Annona squamosa, a tree popularly known in the country as fruta-do-conde or pinha.

20 Dec 2024

New modular strategy reduces piperidine synthesis steps for pharmaceuticals

A team of chemists from Scripps Research and Rice University has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study, published in Science, combines biocatalytic carbon-hydrogen oxidation and radical cross-coupling, offering a streamlined and cost-effective approach to create complex, three-dimensional molecules. This innovation could help accelerate drug discovery and enhance the efficiency of medicinal chemistry.

20 Dec 2024

Meditation eases PTSD symptoms, with transcendental meditation showing major benefits

Research indicates meditation techniques, particularly Transcendental Meditation, significantly alleviate PTSD symptoms, suggesting new avenues for therapy.

19 Dec 2024

Modified lipid nanoparticles for targeted mRNA delivery to the brain

Penn Engineers have modified lipid nanoparticles (LNPs) - the revolutionary technology behind the COVID-19 mRNA vaccines - to not only cross the blood-brain barrier (BBB) but also to target specific types of cells, including neurons.

18 Dec 2024

New study reveals complex attitudes toward psychedelic therapy

In a comprehensive Genomic Press Interview with researchers from Emory University, a new study published today reveals complex attitudes toward psychedelic therapy, with detailed statistics showing both strong support for potential benefits and significant awareness of risks.

18 Dec 2024

Rage has long shadowed American health care. It’s rarely produced big change.

Among the biggest-grossing films in America in February 2002 were a war drama about American troops in Somalia ("Black Hawk Down"), an Arnold Schwarzenegger action movie ("Collateral Damage"), and a future Oscar winner about a brilliant mathematician struggling with schizophrenia ("A Beautiful Mind").

18 Dec 2024

How a duty to spend wisely on worker benefits could loosen PBMs’ grip on drug prices

Ann Lewandowski knows all about pharmacy benefit managers, or PBMs, the companies that shape the U.S. drug market. Her job, as a policy advocate at drugmaker Johnson & Johnson, was to tell patient and physician groups about the PBMs' role in high drug prices.

18 Dec 2024

Breakthrough pig kidney transplant ends dialysis for Alabama woman

An Alabama woman is free from dialysis and in better health after surgeons at NYU Langone Health performed a gene-edited pig kidney transplant last month.

17 Dec 2024

Danish studies find increased risk of optic nerve damage with diabetes medicine

Two independent studies from the University of Southern Denmark (SDU) show that patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye, which can lead to severe and permanent loss of vision.

16 Dec 2024

Smoke from Canadian wildfires leads to surge in heart and lung problems in the U.S.

Wildfire smoke has long been known to exacerbate health problems like heart disease, lung conditions, and asthma, but now a new study finds that smoke from these fires can lead to poor health thousands of miles away.

15 Dec 2024

Gut-targeted antidepressants: A novel approach to battling depression and anxiety

Most of us have experienced the effects of moods and emotions on our gastrointestinal tract, from "butterflies" in the stomach caused by nervousness to a loss of appetite when we're feeling blue.

11 Dec 2024

Imlunestrant offers new hope for ER-positive HER2-negative breast cancer

Imlunestrant, an investigational next-generation selective estrogen receptor degrader (SERD), improved progression-free survival in patients with endocrine therapy-pretreated, ER-positive, HER2-negative advanced breast cancer - as monotherapy in patients with ESR1 mutations and as combination therapy with abemaciclib (Verzenio) in all patients, regardless of ESR1 mutation status - according to results from the phase III EMBER-3 clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

11 Dec 2024