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ACTG initiates clinical trial to evaluate treatment for COVID-19

The AIDS Clinical Trials Group, the world's largest and longest established HIV research network, today announced the initiation of ACTG 5395, a clinical trial to evaluate whether the drug combination hydroxychloroquine and azithromycin can prevent hospitalization and death from COVID-19 (which is caused by infection with the virus SARS-CoV-2).

14 May 2020

Anti-inflammatory drug may improve respiratory function in some severe COVID-19 cases

A small study in Greece found that the clinically approved anti-inflammatory drug anakinra, used to treat rheumatoid arthritis, improved respiratory function in patients with severe coronavirus disease 2019 (COVID-19).

14 May 2020

Does HIV infection increase the severity of COVID-19?

A new study by researchers at the New York University Grossman School of Medicine and published on the preprint server medRxiv* in May 2020 reports that being infected with HIV at the time of acquiring COVID-19 does not significantly increase the severity of illness or the risk of complications.

13 May 2020

C-Path, Provention Bio collaborate to improve scientific community's insight into type 1 diabetes

The Critical Path Institute and Provention Bio, Inc. are proud to announce their collaboration to significantly improve the scientific community's insight into type 1 diabetes through Provention's contribution of data from the Phase III Protégé study of teplizumab to the T1D Trial Outcome Measures Initiative integrated database.

13 May 2020

Non-invasive ventilation mask could reduce aerosolization when treating COVID-19 patients

Led by Lawson Health Research Institute, London Health Sciences Centre, University Health Network and General Dynamics Land Systems-Canada, researchers have designed a non-invasive ventilation mask that could significantly reduce aerosolization - the production of airborne respiratory droplets that may contain viruses or bacteria - when treating patients with COVID-19.

13 May 2020

Researchers urge Ireland government to change recommendations for vitamin D supplements

A new publication from Dr Eamon Laird and Professor Rose Anne Kenny, School of Medicine, and the Irish Longitudinal Study on Ageing (TILDA), in collaboration with Professor Jon Rhodes at University of Liverpool, highlights the association between vitamin D levels and mortality from COVID-19.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Analysis of single-cell data indicates that SARS-Cov-2 targets many cell types

Before it can sicken people, the new coronavirus must first sneak into their cells. But not any cell will do. The virus can enter only those with a certain combination of molecules on their surfaces.

13 May 2020

Experimental two-in-one diabetes shot provides better blood sugar control

The number of people with diabetes has increased from 108 million in 1980 to a staggering 422 million in 2014. In 2016, an estimated 1.6 million deaths were directly caused by diabetes, while another 2.2 million deaths were tied to high blood glucose.

12 May 2020

Organ transplantations plummet amid coronavirus pandemic

The coronavirus disease has spread rapidly across nearly all countries across the globe, with more than 4.25 million people infected. The pandemic has taken a toll on the lives of people, especially those in locked down nations. Aside from the negative impact on economic and social aspects, patients who are sick with other diseases may also suffer from the effects of the pandemic.

12 May 2020

‘No intubation’: Seniors fearful of COVID-19 are changing their living wills

Last month, Minna Buck revised a document specifying her wishes should she become critically ill.

12 May 2020

Study reveals the effect of ancestry on molecular makeup of cancer

Questions about the genealogical imprint of tumors have hovered over cancer research since the completion of the Human Genome Project in 2003.

11 May 2020

ACR releases new guideline for management of gout

Today, the American College of Rheumatology released the 2020 Guideline for the Management of Gout.

11 May 2020

Gum Health Day 2020 to be celebrated worldwide on 12 May

"Say NO to bleeding gums" is the slogan for Gum Health Day 2020, to be celebrated worldwide on 12 May. Its goal is to raise public awareness about bleeding gums, which are usually a sign of a gum disease that will require treatment at the dental practice.

11 May 2020

Study demonstrates dynamic and broad-scale immune alterations in COVID-19 patient

A new case report released on the preprint server medRxiv* provides a detailed longitudinal analysis of the immune response associated with a fatal case of coronavirus disease (COVID-19). It highlights the need for addressing the source of hyper inflammation in the treatment approach.

10 May 2020

RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

9 May 2020

Predicting the dose for repurposing nitazoxanide in COVID-19

A new study published on the preprint server medRxiv in May 2020 reports a model that could help evolve appropriate dosage protocols for future clinical trials of the repurposed drug nitazoxanide in COVID-19 prevention and treatment. The researchers say, “It was possible to achieve plasma and lung tizoxanide concentrations, using proven safe doses of nitazoxanide, that exceed the EC90 for SARS-CoV-2.”

7 May 2020

Modified dialysis device treats COVID-19

As part of a randomized controlled trial, a team from Lawson Health Research Institute is the first in the world to treat a patient with COVID-19 using a modified dialysis device.

7 May 2020

New preclinical study shows promise for treating necrotizing enterocolitis

Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients.

6 May 2020

Study shows thinking and walking speed usually decline together

Do thinking and walking go hand in hand in determining the health course of senior adults? A study published by UT Health San Antonio researchers found that, indeed, the two functions often parallel each other in determining a person's health trajectory.

6 May 2020