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The importance of mitochondrial function in health and disease

The World Mitochondria Society (WMS) is preparing for its annual Targeting Mitochondria 2024 conference, which will focus on innovative strategies to "charge" cells by supplying them with extra mitochondria to enhance cellular function and combat diseases.

18 Sep 2024

OU Health Sciences receives major cancer research grant

A $5.3 million National Institutes of Health grant awarded to the University of Oklahoma Health Sciences will support advanced cancer research in Oklahoma. The Centers of Biomedical Research Excellence (COBRE) grant is designed to build research capacity and help early-career researchers establish independently funded laboratories.

18 Sep 2024

Innovative triplet therapy shows encouraging results in advanced chronic myeloid leukemia

According to researchers at The University of Texas MD Anderson Cancer Center, 80% of patients with previously untreated or relapsed/refractory advanced-phase chronic myeloid leukemia (CML) – including both accelerated or myeloid blast phases of the disease – or Philadelphia chromosome-positive acute myeloid leukemia (AML) achieved a bone marrow remission when treated with a novel combination of decitabine, venetoclax and ponatinib.

17 Sep 2024

Study identifies optimal meditation positions for ADHD patients

ADHD is a developmental condition of brain with symptoms such as inattention, hyperactivity or impulsivity.

17 Sep 2024

Post-treatment lifestyle choices influence long-term outcomes in breast cancer patients

Three studies led by Dana-Farber Cancer Institute researchers have encouraging implications for patients with breast cancer.

17 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the bladder.

17 Sep 2024

Study finds immunotherapy effective for prostate cancer with certain DNA errors

New research has shown that immunotherapy can be effective in treating prostate cancer in men who are selected based on the genetic characteristics of their tumors.

16 Sep 2024

Study highlights limited evidence for antidepressants in treating pain in older adults

University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence.

16 Sep 2024

Addressing anxiety in patients undergoing active surveillance for low-risk cancers

Patients with low-risk cancers undergoing active surveillance face a favorable long-term prognosis. David Haggstrom, M.D., MAS, makes the case that it's time for the medical field to help manage the anxiety caused by waiting.

16 Sep 2024

Study reveals high incidence of orthostatic intolerance in children with long COVID

A new study from Kennedy Krieger Institute shows that the majority of children diagnosed with long COVID are likely to experience orthostatic intolerance (OI), a condition that causes the body to struggle with regulating blood pressure and heart rate when standing up.

16 Sep 2024

ESMO 2024: Promising results in immunotherapy and antibody drug conjugates for gynecological cancers

Studies reported at ESMO 2024 reveal new groups of women with early-stage endometrial and cervical cancers who gain clinically meaningful benefit from adding immunotherapy to current standard treatments, while a first-in-human study found 'promising' antitumor activity with a novel antibody drug conjugate (ADC) targeting the protein claudin 6 in heavily pretreated patients with ovarian and endometrial cancers.

16 Sep 2024

Long-term benefits of immunotherapy highlighted in advanced melanoma and other cancers

Immunotherapy, which works by enabling the body's immune system to recognize and destroy cancer cells improves long-term overall survival in patients with advanced melanoma in results from large international studies reported at ESMO 2024.

16 Sep 2024

ESMO Congress 2024 to unveil future-focused cancer treatments

The ESMO Congress 2024 will hold a press conference to introduce and discuss the "Eyes to the Future" Presidential Symposium 3, that will be presenting prominent approaches that have the potential to become increasingly effective and influential components of cancer treatment in the (near) future.

16 Sep 2024

Brain measurements prove more accurate in predicting mild cognitive impairment

University of Oklahoma researchers recently published a study showing that several measurements of the brain, including blood flow and the brain's ability to compensate for the lack of it, are better predictors of mild cognitive impairment than risk factors like hypertension and high cholesterol.

16 Sep 2024

Novel delivery platform enhances effectiveness of cancer immunotherapy and reduces side effects

Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively.

16 Sep 2024

Hormone therapy found to improve insulin sensitivity in menopausal women

Menopausal women are at greater risk of insulin resistance as a result of declining estrogen levels. Previous studies evaluating the potential benefits of hormone therapy on insulin resistance have produced mixed results.

16 Sep 2024

Combination treatment improves symptoms of agitated delirium in end-of-life cancer patients

Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

16 Sep 2024

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Weill Cornell Medicine and Dana-Farber Cancer Center investigators and their colleagues.

16 Sep 2024

High-dose vitamin D3 cannot be recommended as treatment for metastatic colon cancer

A double-blind randomized phase 3 clinical trial led by Dana-Farber Cancer Institute researchers and conducted across several hundred cancer centers in the U.S. tested the addition of high-dose vitamin D3 to standard treatment for patients with untreated metastatic colorectal cancer.

16 Sep 2024

Therapy News and Research

The importance of mitochondrial function in health and disease

OU Health Sciences receives major cancer research grant

Innovative triplet therapy shows encouraging results in advanced chronic myeloid leukemia

Study identifies optimal meditation positions for ADHD patients

Post-treatment lifestyle choices influence long-term outcomes in breast cancer patients

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Study finds immunotherapy effective for prostate cancer with certain DNA errors

Study highlights limited evidence for antidepressants in treating pain in older adults

Addressing anxiety in patients undergoing active surveillance for low-risk cancers

Study reveals high incidence of orthostatic intolerance in children with long COVID

ESMO 2024: Promising results in immunotherapy and antibody drug conjugates for gynecological cancers

Long-term benefits of immunotherapy highlighted in advanced melanoma and other cancers

ESMO Congress 2024 to unveil future-focused cancer treatments

Brain measurements prove more accurate in predicting mild cognitive impairment

Novel delivery platform enhances effectiveness of cancer immunotherapy and reduces side effects

Hormone therapy found to improve insulin sensitivity in menopausal women

Combination treatment improves symptoms of agitated delirium in end-of-life cancer patients

Combination immunotherapy yields 10-year survival for metastatic melanoma patients

High-dose vitamin D3 cannot be recommended as treatment for metastatic colon cancer

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