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Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied.

7 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

Study reveals a connection between arthritis flare-ups and periodontitis

Regular visits to the dentist might help keep joint pain at bay, too.

6 Mar 2023

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

How estrogen receptor-positive (ER+) breast cancer responds to hormone therapy may hold keys to understanding how it will respond to radiation therapy, and an experimental drug that increases the effectiveness of hormone therapy also overcomes radiation resistance in breast cancer, a study by UT Southwestern Medical Center researchers shows.

6 Mar 2023

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

It may come as a surprise, but bacteria love to grow inside tumors. It's the environment - tumors are typically acidic, have low amounts of oxygen, and are filled with dead cells, which all facilitate bacterial growth.

6 Mar 2023

New research pinpoints key culprit behind brain cancer metastasis in children

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

6 Mar 2023

New ablation technology successful at eliminating episodes of abnormal heart rhythms

A new ablation technology known as pulsed-field ablation was successful at eliminating episodes of abnormal heart rhythms for 12 months in up to two-thirds of patients, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

Experts underscore the need for interventions to meet brain injury caregivers’ needs

Research on caregiving after neurotrauma and neurological disability extends the focus beyond individuals with neurological conditions to caregivers - family, friends, and significant others who also are also greatly impacted.

3 Mar 2023

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

Certain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, according to a new study from University of Pittsburgh and UPMC researchers that may help explain why ovarian cancer patients respond poorly to chemotherapy or relapse after treatment.

3 Mar 2023

New way to carry drugs across the blood-brain barrier using nanoparticles

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Maternal obesity associated with adverse metabolic health outcomes in childhood

Research by the University of the Basque Country indicates that changes caused by maternal obesity could lead to adverse health outcomes in childhood.

3 Mar 2023

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer — altering cancer cells so that they teach the body's immune system to fight the very cancer the cells came from.

2 Mar 2023

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Researchers assessed the role of renalase as an independent predictor of COVID-19-related mortality.

2 Mar 2023

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

1 Mar 2023

Tumor News and Research

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

Study reveals a connection between arthritis flare-ups and periodontitis

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

New research pinpoints key culprit behind brain cancer metastasis in children

New ablation technology successful at eliminating episodes of abnormal heart rhythms

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Experts underscore the need for interventions to meet brain injury caregivers’ needs

Quiescent ovarian cancer cells secrete a protein to induce chemotherapy resistance in neighboring cells

New way to carry drugs across the blood-brain barrier using nanoparticles

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Maternal obesity associated with adverse metabolic health outcomes in childhood

Reprogrammed tumor cells could teach the body's immune system to fight cancer

Study identifies renalase as a novel independent predictor of COVID-19-related mortality

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

What are the clinical considerations of proton radiotherapy for individuals with locally advancing breast cancer?

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

What is the role of B cells in breast cancer pathology?

New mathematical model provides insight into optimal therapeutic strategies for prostate cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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