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MRI scans show potential to replace invasive heart tests by predicting heart failure risk

MRI scans could replace invasive heart tests, as new research shows they can reliably estimate pressures inside the heart to predict if a patient will develop heart failure.

12 Aug 2024

Can odors help fight infection? Nematode research suggests so

Researchers from the University of California, Berkeley, used the nematode model Caenorhabditis elegans to determine whether the olfactory nervous system could non-autonomously control the mitochondrial unfolded protein response in response to cellular stress.

12 Aug 2024

Can how often you eat meat raise your risk of colorectal cancer?

Study shows that high processed meat intake significantly increases colorectal neoplasm risk, with effects equivalent to a 19 percentile increase in genetic risk scores, while red meat consumption shows no significant association.

11 Aug 2024

Prenatal BPA exposure tied to autism risk in boys

Study reveals that prenatal exposure to BPA disrupts aromatase activity in male brains, potentially leading to autism-like symptoms. Treatment with 10-HDA shows promise in reversing these effects.

11 Aug 2024

New insights into retrotransposon-derived DNA zip codes in myeloma cells

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization."

9 Aug 2024

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

Most tumors release various signaling molecules to support their incessant growth, invasion, and metastasis.

9 Aug 2024

Controllable chiral switching in double-helical foldamers for advanced molecular systems

The deoxyribonucleic acid or DNA, the molecular system that carries the genetic information of living organisms, can transcribe and amplify information using its two helical strands.

9 Aug 2024

Machine learning revolutionizes gene delivery

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.

9 Aug 2024

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain.

8 Aug 2024

Increased skin-to-skin time linked to better neurodevelopment

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Study reveals key brain cells help resist food temptations in favor of exercise

Hypocretin/orexin neurons (HONs) are crucial for resisting temptation and choosing exercise over highly palatable foods. This finding highlights potential targets for promoting physical activity and combating obesity.

7 Aug 2024

Social genomics: How friends' genes impact a person's mental health

Mom always said, "Choose your friends wisely." Now a study led by a Rutgers Health professor shows she was onto something: Their traits can rub off on you – especially ones that are in their genes.

7 Aug 2024

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression.

7 Aug 2024

Healthy diet and exercise can mitigate genetic risk for type 2 diabetes, study finds

A new study from the University of Eastern Finland is the first in the world to show that a healthy diet and regular exercise reduce the risk of type 2 diabetes even in individuals with a high genetic risk.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

Genetic News and Research

MRI scans show potential to replace invasive heart tests by predicting heart failure risk

Can odors help fight infection? Nematode research suggests so

Can how often you eat meat raise your risk of colorectal cancer?

Prenatal BPA exposure tied to autism risk in boys

New insights into retrotransposon-derived DNA zip codes in myeloma cells

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

Controllable chiral switching in double-helical foldamers for advanced molecular systems

Machine learning revolutionizes gene delivery

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

Increased skin-to-skin time linked to better neurodevelopment

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

New treatment boosts pluripotent stem cell production in mice

Study reveals key brain cells help resist food temptations in favor of exercise

Social genomics: How friends' genes impact a person's mental health

Decoding glioblastoma: New insights into molecular subtypes and mesenchymal transition mechanisms

Healthy diet and exercise can mitigate genetic risk for type 2 diabetes, study finds

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

METRNL protein identified as key player in cancer progression

Study advances understanding of complex neurological disorder

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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