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Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

New imaging method could help make better decisions on personalized cancer treatment

Decisions on cancer treatment could become better tailored to individual patients with the adoption of a new imaging method being developed by University of Michigan researchers that maps the chemical makeup of a patient’s tumor.

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Could spices boost protein intake in older adults?

Poor eating often exacerbates aging problems, resulting in inadequate protein intake among older adults. This, in turn, may cause muscle wasting, reduced function, and poor quality of life. A new research paper looks at the role of spices in boosting the attractiveness of typical foods in this age group.

1 Mar 2023

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

Pheochromocytoma is a rare tumor, with an incidence of three to eight cases per million population per year.

28 Feb 2023

Applying an evolutionary perspective to medicine can spark biomedical innovations

The word 'evolution' may bring to mind dusty dinosaur bones, but it impacts our health every day. For example, even though antibiotics were invented only a century ago, the evolution of antibiotic resistance is already a major concern.

28 Feb 2023

New funding to accelerate development of potential anti-cancer compound into the clinic

For the past few decades, Dr. Iwao Ojima has been working in his Stony Brook University Department of Chemistry Laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) to develop next-generation anti-cancer agents.

28 Feb 2023

First small molecules designed to stimulate immune cells against neuroblastoma

An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer.

28 Feb 2023

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice suggests.

28 Feb 2023

Inexpensive combo-chemotherapy found to be better tolerated than BCG for common bladder cancer

An on-going, worldwide shortage of bacillus Calmette-Guérin (BCG) means that many patients with a common and serious type of bladder cancer have limited access to this effective standard of care treatment.

28 Feb 2023

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

High throughput device isolates and classifies metabolically active CTCs

Researchers from the University of Technology Sydney have developed a new device that can detect and analyze cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress.

27 Feb 2023

Experts develop commercial formulation Campto for colorectal cancer

Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer.

25 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Head injuries may contribute to the development of glioma

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

24 Feb 2023

Tumor News and Research

Promising alternative strategy for islet transplantation in people with type 1 diabetes

New imaging method could help make better decisions on personalized cancer treatment

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Could spices boost protein intake in older adults?

Largest genomic study focuses on the prognosis of metastatic pheochromocytomas

Applying an evolutionary perspective to medicine can spark biomedical innovations

New funding to accelerate development of potential anti-cancer compound into the clinic

First small molecules designed to stimulate immune cells against neuroblastoma

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Inexpensive combo-chemotherapy found to be better tolerated than BCG for common bladder cancer

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Researchers explore potential new target for cancer immunotherapy

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

High throughput device isolates and classifies metabolically active CTCs

Experts develop commercial formulation Campto for colorectal cancer

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Head injuries may contribute to the development of glioma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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