Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

A study measured neutralization of SARS-CoV-2 and vaccine responses in immunocompromised patients with systemic inflammatory diseases.

11 Aug 2021

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

In the current study, the authors evaluate several different competitive ELISAs that could be used to measure serum antibodies.

11 Aug 2021

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

A recent study discusses the clinical characteristics and outcomes of patients with SARDs who were previously vaccinated against SARS-CoV-2.

11 Aug 2021

COVID-19 vaccine likely protects people living with HIV, study shows

A Johns Hopkins Medicine research team has shown that people living with the human immunodeficiency virus (HIV) are likely to be protected against SARS-CoV-2, the virus that causes COVID-19, if they are fully vaccinated.

11 Aug 2021

Small NIH clinical trial shows that new monoclonal antibody can prevent malaria

One dose of a new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to nine months in people who were exposed to the malaria parasite.

11 Aug 2021

COVID-19 booster shot in autumn will effectively protect against existing and future variants

Scientists at the University of Nottingham have confirmed that an autumn 'booster' dose of a Covid-19 vaccine will be an effective way to protect people from existing, and potentially future, variants of concern.

11 Aug 2021

COVID-19 vaccines offer better protection than natural immunity alone

Now, the U.S. Centers for Disease Control and Prevention (CDC) reports that among people who were previously infected with SARS-CoV-2, those who were still unvaccinated are more likely to be reinfected than those fully vaccinated after prior infection.

11 Aug 2021

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Scientists from Germany and Belgium have recently described the immunogenicity of a plant-based virus-like particle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vaccine induces robust antibody and T cell responses for at least 6 months. Moreover, the vaccine demonstrates potent neutralizing efficacy against the B.1.1.7, B.1.351, and P1 variants of SARS-CoV-2.

11 Aug 2021

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

A new study explores the polyclonal antibody response to SARS-CoV-2 in greater detail.

10 Aug 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

A new study finds that heavy alcohol drinking is associated with an increase in the number of COVID-19 cases among American college students.

10 Aug 2021

Natural vs. vaccine-induced COVID-19 immunity

A new paper discusses the protection offered by immunity against COVID-19 following vaccination as compared to natural infection.

10 Aug 2021

New platform can quickly identify common mutations on the SARS-CoV-2 virus

Researchers at the University of Colorado Boulder have developed a platform which can quickly identify common mutations on the SARS-CoV-2 virus that allow it to escape antibodies and infect cells.

10 Aug 2021

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

A pilot study has begun to assess the antibody response to a third dose of an authorized COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine.

10 Aug 2021

New estimate of total immunity to SARS-CoV-2 in Texas

According to researchers in Texas, a lack of appropriate testing in the US has led to an underestimation of seroprevalence in the U.S., thus making it difficult to estimate population immunity to SARS-CoV-2 or vaccination.

10 Aug 2021

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

A recent study in Colorado used real-world data to evaluate if individuals with chronic conditions have reduced antibody response to COVID-19 mRNA vaccines. The study investigated whether some medical conditions may impact antibody response to the mRNA vaccines.

9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

New insight into impact of SARS-CoV-2 mutations on receptor binding

A recent study by Canadian researchers, currently available on the bioRxiv* preprint server, contributes to the growing body of literature on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by appraising the impact of single mutations on their overall antigenicity and binding affinity for the angiotensin-converting enzyme 2 (ACE2) receptor.

9 Aug 2021

Long COVID may be due to persistent immune disturbances

A new study discusses abnormalities in the immune response following COVID-19 in samples collected from patients who have recovered from COVID-19.

8 Aug 2021

Antibody News and Research

Further Reading

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

COVID-19 vaccine likely protects people living with HIV, study shows

Small NIH clinical trial shows that new monoclonal antibody can prevent malaria

COVID-19 booster shot in autumn will effectively protect against existing and future variants

COVID-19 vaccines offer better protection than natural immunity alone

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

Natural vs. vaccine-induced COVID-19 immunity

New platform can quickly identify common mutations on the SARS-CoV-2 virus

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

New estimate of total immunity to SARS-CoV-2 in Texas

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

New insight into impact of SARS-CoV-2 mutations on receptor binding

Long COVID may be due to persistent immune disturbances

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