Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Understanding how memories are made, retrieved, and eventually fade over a lifetime is the stuff of poems and song. To medical researchers, solving the mysteries of memory is even more elusive.

1 Jun 2017

Micropollutants exert stress on aquatic ecosystems

In Switzerland, more than 30,000 different substances are used on a daily basis in innumerable products - pharmaceuticals, cosmetics, cleaning agents or industrial chemicals.

1 Jun 2017

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

Scientists have, for the first time, characterized the molecular markers that make the brain's front lines of immune defense--cells called microglia--unique.

31 May 2017

MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017

Study sheds light on mechanisms that maintain gene activity in embryonic stem cells

Researchers from Turku, Finland, have discovered new information about the mechanisms which maintain gene activity in human embryonic stem cells.

31 May 2017

Cancer treatment may be effective therapy for psoriasis

HDAC inhibitors, already widely used to treat cancer, may be an effective therapy for psoriasis as well, scientists report.

31 May 2017

Kyoto University researchers identify specific gene as key regulator in iron uptake

Maintaining a good balance of iron in the body is necessary for health: too little can lead to anemia, but too much can cause debilitating disorders such as hemochromatosis.

30 May 2017

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

Dragon Master Foundation has announced plans to provide $300,000 in funding for the first clinical trial that will make patient data available live in the cloud while the trial is underway.

27 May 2017

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Every animal starts as a clump of cells, which over time multiply and mature into many different types of cells, tissues, and organs.

26 May 2017

Study reveals how enzyme allows brain tumors to grow despite harsh surroundings

All cancer tumors have one thing in common – they must feed themselves to grow and spread, a difficult feat since they are usually in a tumor microenvironment with limited nutrients and oxygen.

26 May 2017

BU professor receives Research Innovation and Translation Achievement Award from ATS

Avrum Spira, MD, MSc, professor of medicine, pathology and bioinformatics at Boston University School of Medicine, is the inaugural recipient of the Research Innovation and Translation Achievement Award from the American Thoracic Society.

24 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Researchers from Princeton University's Department of Molecular Biology have identified a small RNA molecule that helps maintain the activity of stem cells in both healthy and cancerous breast tissue.

23 May 2017

Researchers visualize precise mechanisms of calcium-dependent kinase during synaptic plasticity

Researchers at Max Planck Florida Institute for Neuroscience optimized imaging methods to visualize the activation of CaMKII during synaptic plasticity with unprecedented resolution.

18 May 2017

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Seventh Wave Laboratories, a consulting-based contract research organization that assesses the safety and efficacy of pharmaceutical products and medical devices, has announced an exclusive collaboration with Yecuris Corporation, a global leader in the development and use of humanized models in drug development research.

18 May 2017

Microbes can manipulate molecular machinery of host cells to influence health

All animals -- from sea sponges to modern-day humans -- evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology as our own tissues and organs.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

Analysis of a patient's gut microbiome - the microbial population of the gastrointestinal tract - may be able to predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.

16 May 2017

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

University of Oregon researchers using Drosophila have identified a steroid hormone that triggers a vital transition in early brain development in which neural stem cells properly change gears to produce different kinds of neurons.

15 May 2017

Gene Expression News and Research

Further Reading

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Micropollutants exert stress on aquatic ecosystems

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

MGH scientists show how Shigella survives journey from mouth to the colon

Study sheds light on mechanisms that maintain gene activity in embryonic stem cells

Cancer treatment may be effective therapy for psoriasis

Kyoto University researchers identify specific gene as key regulator in iron uptake

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Study reveals how enzyme allows brain tumors to grow despite harsh surroundings

BU professor receives Research Innovation and Translation Achievement Award from ATS

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Researchers visualize precise mechanisms of calcium-dependent kinase during synaptic plasticity

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Microbes can manipulate molecular machinery of host cells to influence health

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy