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Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Hesperos Inc., pioneers of the Human-on-a-Chip in vitro system, today announced the publication of a new peer-reviewed publication that describes how the company’s technology can be used to investigate immune responses following treatment with biological therapeutics for multi-organ systemic diseases, including cancer, infectious diseases and inflammatory disorders.

4 Jun 2020

Scientists uncover why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

3 Jun 2020

Kawasaki-like inflammatory syndrome appears to be more common in children of African ancestry

An inflammatory syndrome in children and adolescents, believed to be linked to covid-19, seems to be more common among children of African ancestry, finds a small study from a hospital in Paris, published by The BMJ today.

3 Jun 2020

Number of heart attack patients has dropped over 50% during COVID-19 outbreak

The number of heart attack patients seeking urgent hospital care has dropped by more than 50% during the COVID-19 outbreak, according to an extensive worldwide survey by the European Society of Cardiology (ESC).

3 Jun 2020

ICUs become a ‘delirium factory’ for COVID patients

Doctors are fighting not only to save lives from COVID-19, but also to protect patients' brains.

3 Jun 2020

Novel 3D imaging technique could prove to be valuable for wide range of studies

A collaboration between Colorado State University and University of Illinois at Urbana-Champaign resulted in a new, 3D imaging technique to visualize tissues and other biological samples on a microscopic scale, with potential to assist with cancer or other disease diagnoses.

2 Jun 2020

A remote optical control for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

1 Jun 2020

Research suggests new approach to therapeutic intervention for ALS

Amyotrophic lateral sclerosis (ALS) is one of the most devastating adult-onset neurodegenerative diseases. Patients, including the late actor/playwright Sam Shepard, become progressively weaker and eventually paralyzed as their motor neurons degenerate and die.

1 Jun 2020

Researchers use optical mapping system to observe the effect of hydroxychloroquine

The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms.

1 Jun 2020

Anesthetic drug Ketamine uses serotonin receptors to relieve depression

Ketamine is a drug used to induce general anesthesia. It has also been found to act rapidly to relieve depression that has failed to respond to two other rounds of medication. A new study published in the journal Translational Psychiatry in May 2020 reports the mechanism of action of the drug, which was hitherto unknown. This could help find new ways to treat this debilitating and sometimes fatal condition.

31 May 2020

Significant number of COVID-19 positive cases asymptomatic, raising transmission concerns

There have been many instances of people testing positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who have no symptoms of the infection whatsoever. These asymptomatic patients are, however, still capable of spreading the infection without being aware of it, say experts.

31 May 2020

University of Freiburg receives 30 million euros for excellent research

The German Research Foundation has approved a new proposal for a collaborative research center under the leadership of the Institute for Experimental Cardiovascular Medicine at the University Heart Centre Freiburg · Bad Krozingen.

30 May 2020

Expert offers COVID-19 guidance for patients with COPD

Chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema, is a chronic lung disease that makes it hard to breathe. The disease affects millions of Americans and is the fourth leading cause of disease-related death in the U.S. People with COPD have a higher risk of more severe illness from COVID-19 due to their existing lung problems.

30 May 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

Common assumptions about mercury exposure should be reexamined, show studies

Small-scale gold mining in the Peruvian Amazon poses a health hazard not only to the miners and communities near where mercury is used to extract gold from ore but also to downstream communities hundreds of kilometers away from where people eat mercury-contaminated river fish as part of their diet.

29 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

The main thoroughfare that carries oxygen-rich blood from the heart to the abdomen is known as the abdominal aorta.

28 May 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

A closer look at TMPRSS2: This could help treat COVID-19

The transmembrane protease serine-type 2 (TMPRSS2) protein plays a key role in COVID-19 infection since it primes the viral spike protein to allow viral entry into the target cell. A new study by researchers at Imperial College London and published on the preprint server bioRxiv in May 2020 describes the protein, which could be an attractive drug target to help manage COVID-19.

28 May 2020

Physical activity prevents the accumulation of damaged proteins and keeps muscles healthy

Researchers at the University of Copenhagen's Department of Nutrition, Exercise and Sports have demonstrated that physical activity prompts a clean-up of muscles as the protein Ubiquitin tags onto worn-out proteins, causing them to be degraded.

28 May 2020