Therapeutics News and Research

RSS

Study uncovers common neural mechanism for cognitive impairment in autism and schizophrenia

Many neurodevelopmental disorders share similar symptoms, such as learning disabilities or attention deficits.

30 Jun 2021

SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

In an effort to hasten the research on identifying antiviral drugs for SARS-CoV-2 infection, researchers from the U.S. and Switzerland performed extensive drug screening for antiviral activity using live virus infection in human respiratory cells. As a result, they identified a set of possible drug candidates that could potentially be tested in clinical trials.

30 Jun 2021

Researchers identify key protein that allows cancer-destroying viruses to enter tumor cells

Researchers from the Laboratory of Oncolytic-Virus-Immuno-Therapeutics (LOVIT) at the LIH Department of Oncology (DONC) are working on the development of novel anticancer strategies based on oncolytic viruses, "good" viruses that can specifically infect, replicate in and kill cancer cells.

30 Jun 2021

Scientists outline new target for treating type 2 diabetes

This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.

30 Jun 2021

Promising preclinical results of new dementia treatment candidate set the stage for human trials

Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.

29 Jun 2021

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

Skoltech researchers and their colleagues from Russia and the UK investigated the safety and efficacy of new chemistry in antisense oligonucleotides used to treat spinal muscular atrophy (SMA), a debilitating genetic disease.

29 Jun 2021

Study suggests vitamin B12 as a SARS-CoV-2 antiviral

Researchers in the UK and Spain have used a novel drug screening approach to identify compounds that could serve as effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

28 Jun 2021

UIC researchers offer free rapid diagnostic testing for COVID-19 in vulnerable Chicago communities

Researchers at the University of Illinois Chicago are offering free rapid diagnostic testing for COVID-19 in vulnerable Chicago communities and performing genomic sequencing on the samples to identify variants.

28 Jun 2021

Metabolic activators can reduce recovery time in patients with mild-to-moderate Covid-19

Metabolic activators were found to reduce recovery time by as many as 3.5 days in patients with mild-to-moderate Covid-19, according to a Swedish-British study published today in Advanced Science.

28 Jun 2021

Connective tissue protein promotes immune responses that fight bacterial infections

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study finds.

28 Jun 2021

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Experts estimate more than 6 million Americans are living with Alzheimer's dementia. But a recent study, led by the University of Cincinnati, sheds new light on the disease and a highly debated new drug therapy.

28 Jun 2021

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

The National Cancer Institute has awarded the Lung Cancer Metabolism Working Group at Moffitt Cancer Center with a Research Program Project Grant (P01CA250984).

28 Jun 2021

New analysis links distinct patterns of genetic mutations with OCD

In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans.

28 Jun 2021

Researchers develop engineered yeast probiotic for treatment of inflammatory bowel disease

The world of microbes living in the human gut can have far-reaching effects on human health. Multiple diseases, including inflammatory bowel disease (IBD), are tied to the balance of these microbes, suggesting that restoring the right balance could help treat disease.

28 Jun 2021

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Achieving gender equality within global health

News-Medical spoke to Dr. Claire Bayntun about her incredible career in global health, and how we can achieve gender equality within healthcare settings.

28 Jun 2021

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Oncotarget published "Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells" which reported that to guide studies in cancer patients, relacorilant, an investigational selective GR modulator that antagonizes cortisol activity, was assessed in various tumor types, with multiple cytotoxic combination partners, and in the presence of physiological cortisol concentrations.

28 Jun 2021

Tocilizumab and sarilumab shown to be effective in critical COVID-19

A new study, released as a preprint on the medRxiv* server, describes how a team of researchers from the University Medical Center Utrecht in the Netherlands explored the efficacy of four monoclonal antibodies that antagonize powerful pro-inflammatory pathways. The team sought to determine which were useful in treating critically ill COVID-19 patients on organ support.

28 Jun 2021

Research shows how circadian control of glucose production is disrupted during lung cancer progression

New research from the University of California, Irvine reveals how the circadian regulation of glucose production in the liver is lost during lung cancer progression, and how the resulting increase in glucose production may fuel cancer cell growth.

25 Jun 2021

New technology can help improve various materials implanted into the human body

Medical materials that can be inserted into the human body have been used for decades in the field of regenerative medicine - for example, stents that can help dilate clogged blood vessels and implants that can replace teeth or bones.

25 Jun 2021

Therapeutics News and Research

Study uncovers common neural mechanism for cognitive impairment in autism and schizophrenia

SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

Researchers identify key protein that allows cancer-destroying viruses to enter tumor cells

Scientists outline new target for treating type 2 diabetes

Promising preclinical results of new dementia treatment candidate set the stage for human trials

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

Study suggests vitamin B12 as a SARS-CoV-2 antiviral

UIC researchers offer free rapid diagnostic testing for COVID-19 in vulnerable Chicago communities

Metabolic activators can reduce recovery time in patients with mild-to-moderate Covid-19

Connective tissue protein promotes immune responses that fight bacterial infections

Alzheimer's symptoms could be due to decline in brain protein not accumulation of amyloid plaques

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

New analysis links distinct patterns of genetic mutations with OCD

Researchers develop engineered yeast probiotic for treatment of inflammatory bowel disease

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Achieving gender equality within global health

Antagonism of glucocorticoid receptors promotes apoptosis in solid tumor cells

Tocilizumab and sarilumab shown to be effective in critical COVID-19

Research shows how circadian control of glucose production is disrupted during lung cancer progression

New technology can help improve various materials implanted into the human body

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News