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Out-of-sync gamma waves in the brain may underlie learning issues in psychiatric disorders

A new UC San Francisco study has pinpointed a specific pattern of brain waves that underlies the ability to let go of old, irrelevant learned associations to make way for new updates.

1 Jun 2020

Deep vein clots in critical COVID-19 illness

A new research paper published in the journal JAMA Network Open in May 2020 reports a high incidence of deep vein clots in patients with severe COVID-19 at a single French medical center. This could indicate the need for systematic anticoagulant therapy in these patients as a preventive measure.

31 May 2020

Neanderthal gene in women boosts infertility

It is still unclear why some women go into labor for long periods, and some face a high risk of childbirth. Also, some women fall pregnant quickly, while others may take years before they conceive. The answer may be due to a gene inherited from the Neanderthals, an extinct species or subspecies of archaic humans who lived in Eurasia until about 40,000 years ago.

31 May 2020

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

A new meta-analysis published on the preprint server medRxiv by the researchers from the United States and Greece reveals that the likelihood of death is 65% higher in hospitalized coronavirus disease (COVID-19) patients with diabetes when compared to non-diabetics – urging the adequate glucose control in the era of the pandemic.

31 May 2020

Study explores how parasites respond to climate change

Warming events are increasing in magnitude and severity, threatening many ecosystems worldwide. As the global temperatures continue to climb, it also raises uncertainties as to the relationship, prevalence, and spread of parasites and disease.

30 May 2020

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

Results of the NRG Oncology phase III clinical trial NRG-GY004 indicated that the addition of the investigational agent cediranib to olaparib and standard platinum-based chemotherapy did not improve progression-free survival (PFS) outcomes for women with platinum-sensitive ovarian cancer; however, activity between the treatments was similar in patients.

30 May 2020

A closer look at TMPRSS2: This could help treat COVID-19

The transmembrane protease serine-type 2 (TMPRSS2) protein plays a key role in COVID-19 infection since it primes the viral spike protein to allow viral entry into the target cell. A new study by researchers at Imperial College London and published on the preprint server bioRxiv in May 2020 describes the protein, which could be an attractive drug target to help manage COVID-19.

28 May 2020

Research provides important insights into genetic adaptation of SARS-CoV-2 to humans

In their groundbreaking paper available on the preprint server medRxiv, University of Pittsburgh researchers were appraising signals of SARS-CoV-2 genome evolution and found that purifying selection (i.e., removal of deleterious mutations) represents the dominant trait during early coronavirus disease (COVID-19) pandemic - suggesting that the virus will evolve as it diversifies in a growing number of hosts.

28 May 2020

Characterizing immune cells in malignant brain tumors

It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary.

28 May 2020

Researchers study the effect of major life events on wellbeing

Major life events such as marriage, death of a loved one or bankruptcy all affect our wellbeing. Now, for the first time, researchers have compared the differing impact of these events on the happiness and life satisfaction and how long that impact lasts.

28 May 2020

SARS-CoV-2 RNA in blood tests not associated with infectious virus

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged hospitals and laboratory services worldwide. Diagnostic testing for SARS-CoV-2 initially lagged but is now primarily based on the use of reverse transcriptase-polymerase chain reaction (RT-PCR) to detect viral nucleic RNA in the samples. However, viral RNA has also been reported in several small series of cases, though its significance and frequency remain unclear.

27 May 2020

How India's lockdown has affected mental health

India’s public landscape has transformed dramatically over the last couple of months, with the most prolonged lockdown that the present generation can remember. Declared on March 24, 2020, the lockdown ensured that hundreds of millions of people were effectively confined to home, except when they ventured out, armed with a self-attested affidavit, to stock up on essentials.

27 May 2020

Genomic analysis compares ADHD-related genetic variants in Neanderthal and modern human samples

The frequency of genetic variants associated with attention-deficit/hyperactivity disorder (ADHD) has decreased progressively in the evolutionary human lineage from the Palaeolithic to nowadays, according to a study published in the journal Scientific Reports.

27 May 2020

Risk of anxiety disorder, associated problems increases drastically in users of high-potency cannabis

Users of high-potency cannabis are four times more likely to report associated problems, and twice as likely to report anxiety disorder, than users of lower-potency strains, according to new research from the University of Bristol.

27 May 2020

Researchers develop rapid electro-optical test to identify COVID-19 carriers

Ben-Gurion University of the Negev's Prof. Gabby Sarusi has developed a one-minute electro-optical test of nose, throat, or breath samples that will identify both asymptomatic and affected carriers of the COVID-19 virus in under one minute with greater than 90% accuracy.

27 May 2020

Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

The purported "game-changer" anti-malarial drug Hydroxychloroquine, which was claimed to be effective in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and also helping better outcomes in COVID-19 patients, seems to have failed in clinical trials.

25 May 2020

Molecular testing rates in most countries less than 50%, IASLC survey finds

Access to targeted therapies for lung cancer depends on accurate identification of patients' biomarkers through molecular testing, but survey results published today in the Journal of Thoracic Oncology suggest that many international clinicians are unaware of evidence-based guidelines that support the use of molecular testing.

20 May 2020

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Prostate cancer patients who do not respond well to PSMA-targeted therapy often have potentially treatable mutations in their DNA damage-repair genes, according to research published in the May issue of The Journal of Nuclear Medicine.

20 May 2020

Early life antibiotic exposure linked to increased risk of childhood obesity

Very young children exposed to antibiotics at an early age (from birth to 12 months) are associated with higher risks of childhood obesity and increased adiposity in early to mid-childhood.

19 May 2020

A new treatment option for activating cellular defenses against neurodegenerative disease

Talk about motherly instincts: Biologists at the University of Iowa have learned that female roundworms can alert their future offspring of dangers they will encounter when born, and the mothers pass on these warnings even before the offspring have been conceived.

19 May 2020

Frequency News and Research

Out-of-sync gamma waves in the brain may underlie learning issues in psychiatric disorders

Deep vein clots in critical COVID-19 illness

Neanderthal gene in women boosts infertility

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

Study explores how parasites respond to climate change

Study compares cediranib plus olaparib and standard of care therapy for platinum-sensitive ovarian cancer

A closer look at TMPRSS2: This could help treat COVID-19

Research provides important insights into genetic adaptation of SARS-CoV-2 to humans

Characterizing immune cells in malignant brain tumors

Researchers study the effect of major life events on wellbeing

SARS-CoV-2 RNA in blood tests not associated with infectious virus

How India's lockdown has affected mental health

Genomic analysis compares ADHD-related genetic variants in Neanderthal and modern human samples

Risk of anxiety disorder, associated problems increases drastically in users of high-potency cannabis

Researchers develop rapid electro-optical test to identify COVID-19 carriers

Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

Molecular testing rates in most countries less than 50%, IASLC survey finds

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Early life antibiotic exposure linked to increased risk of childhood obesity

A new treatment option for activating cellular defenses against neurodegenerative disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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