Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Analyzing single-cell RNA data in pre-malignant tumors

RNA sequencing is basically the isolation of RNA from cells and the use of reverse transcriptase to turn the RNA into DNA. You can then use your standard DNA sequencing technologies to quantify the cDNA that you obtained from the reverse transcription reaction.

12 May 2017

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Researchers have identified a microRNA biomarker that demonstrates a strong association with the incidence of atrial fibrillation, the most common abnormal heart rhythm that affects more than 2.7 million Americans.

11 May 2017

Chemical stimuli by small molecule can improve production of cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage.

11 May 2017

Breast cancer drug offers protection against obesity-related metabolic disorders

Tamoxifen, a selective estrogen receptor modulator, is the gold standard for endocrine treatment of estrogen-receptor positive breast cancer.

11 May 2017

BGRF scientists help develop AI to expedite drug development for age-related conditions

The Chief Science Officer of the Biogerontology Research Foundation will present new research on artificial intelligence for drug discovery at the NVIDIA Graphics Technology Conference at the San Jose Convention Center, on Wednesday, May 10, 1:00 PM - 1:50 PM alongside two AI scientists from the BGRF and Insilico Medicine, where they will deliver a presentation titled "Applications of Generative Adversarial Networks to Drug Discovery in Oncology and Infectious Diseases".

9 May 2017

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Previous research has demonstrated that saturated fat is more fattening and less muscle building than polyunsaturated fats. A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

8 May 2017

Study shows how influenza A hijacks human cellular machinery to replicate

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.

5 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Men and women differ in obvious and less obvious ways -- for example, in the prevalence of certain diseases or reactions to drugs. How are these connected to one's sex? Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed -- copied out to make proteins -- differently in the two sexes.

4 May 2017

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

A team of Florida State University researchers is using mathematical modeling to find the best and most effective chemotherapy treatments for cancer patients.

4 May 2017

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, today announced publication of an article in the journal Nature of a collaborative research study with researchers at the Stanford University School of Medicine.

From 10x Genomics, Inc. 4 May 2017

Specific genetic changes in the placenta of women may serve as biomarker to predict newborn health

UCLA scientists have discovered specific genetic changes in the placentas of women who gave birth to growth-restricted infants. These changes appear to sabotage the ability of the placenta to grow blood vessels and adequately nourish the fetus, interfering with the infant's growth in the womb.

3 May 2017

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

The formation of a human embryo starts with the fertilization of the oocyte by the sperm cell. This yields the zygote, the primordial cell that carries one copy each of the maternal and paternal genomes.

2 May 2017

German scientists unravel defense strategy of mushrooms against insect larvae

Some mushrooms produce long-chain unsaturated carboxylic acids as their chemical defense against insect larvae. The biosynthesis of these polyenes relies on only one enzyme, as German scientists have now discovered.

29 Apr 2017

Study sheds new light on evolutionary origin of the vertebrate brain

A study recently published in PLOS Biology provides information that substantially changes the prevailing idea about the brain formation process in vertebrates and sheds some light on how it might have evolved.

28 Apr 2017

Researchers take important step toward using transplanted fetal cells to treat liver failure

In a new study, researchers demonstrate successful transplantation of fetal rat liver cells to an injured adult rat liver. The work is an important step toward using transplanted cells to treat liver failure, which currently requires an organ transplant.

26 Apr 2017

Removing senescent cells from joints could reverse progression of osteoarthritis

In a preclinical study in mice and human cells, researchers report that selectively removing old or 'senescent' cells from joints could stop and even reverse the progression of osteoarthritis.

26 Apr 2017

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Vitamin A is an essential nutrient that the human body needs to function properly. But new research presented today at the American Physiological Society annual meeting at Experimental Biology 2017 in Chicago suggests that normal levels of vitamin A within a high-fat diet can negatively affect expression of liver genes associated with glucose and fat metabolism.

26 Apr 2017

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

About 8 percent of people will develop post-traumatic stress disorder at some point in their lives, according to the U.S. Department of Veterans Affairs, yet treatments for this debilitating condition remain limited.

25 Apr 2017

New technique can test effectiveness of treatments for breast cancer metastases in bone

A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone. The study appears in Nature Communications.

21 Apr 2017

Gene Expression News and Research

Further Reading

Analyzing single-cell RNA data in pre-malignant tumors

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Chemical stimuli by small molecule can improve production of cartilage cells

Breast cancer drug offers protection against obesity-related metabolic disorders

BGRF scientists help develop AI to expedite drug development for age-related conditions

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Study shows how influenza A hijacks human cellular machinery to replicate

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Researchers use mathematical modeling to find effective chemotherapy treatments for cancer patients

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

Specific genetic changes in the placenta of women may serve as biomarker to predict newborn health

EPFL researchers discover protein that kick-starts gene expression in nascent embryos

German scientists unravel defense strategy of mushrooms against insect larvae

Study sheds new light on evolutionary origin of the vertebrate brain

Researchers take important step toward using transplanted fetal cells to treat liver failure

Removing senescent cells from joints could reverse progression of osteoarthritis

Vitamin A combined with high-fat diet may lead to increased risk for obesity and diabetes

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

New technique can test effectiveness of treatments for breast cancer metastases in bone

Industry Focus eBook - Biotechnology (4th edition) eBook

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