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Collaborative study offers hope for syphilis vaccine development

Syphilis cases have surged worldwide, leaving public health officials scrounging for ways to stop the spread. Now, a large, collaborative study of syphilis genetics from four continents has found hints of a possible target for a vaccine.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

FIND Lp(a) machine learning model aims to transform cardiovascular disease screening

Today, the Family Heart Foundation®, a leading research and advocacy organization, announced the successful completion of the Flag, Identify, Network and Deliver™ “FIND Lp(a)” machine learning model – a first-of-its-kind offering being implemented in care delivery systems across the United States.

19 Sep 2024

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Rice University and Baylor College of Medicine have received $2.8 million in funding from the National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), for research on reducing inflammation and lung damage in acute respiratory distress syndrome (ARDS) patients.

19 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Researchers discovered that IBD significantly increases the risk of developing T1D, and this association works both ways, independent of genetics and familial factors. The strongest link was seen in ulcerative colitis patients.

19 Sep 2024

Early intervention key for mental health in children with cystic fibrosis

A University at Buffalo psychiatrist who has played a critical role in getting mental health screening and treatment integrated into routine care for adults and adolescents with cystic fibrosis (CF) has been awarded $3 million from the Cystic Fibrosis Foundation to focus on the mental health of children with the disease.

19 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Asimov, the synthetic biology company advancing the design and production of therapeutics, today announced the launch of the AAV Edge System, a comprehensive suite of tools for adeno-associated viral (AAV) gene therapy design and manufacturing.

18 Sep 2024

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Researchers explore the global rise in early-onset cancers, linking environmental exposures and lifestyle changes to the surge, and advocate for tailored prevention and treatment strategies.

18 Sep 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

New tool unveils dynamic changes in brain extracellular matrix

Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM).

18 Sep 2024

Study helps explain why having ApoE4 increases risk of neurodegeneration

A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer's disease—increases the risk of neurodegeneration and white matter damage.

18 Sep 2024

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

Scientists have pinpointed thousands of genetic changes in a gene that may increase a person's risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.

18 Sep 2024

Exposure to styrene and ethylbenzene elevates diabetes risk

Type 2 diabetes mellitus (T2DM) is a critical public health issue, with its prevalence expected to rise sharply worldwide.

18 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

Genome-wide association study identifies genetic risk factors for dementia

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease.

18 Sep 2024

Lipid molecule fuels cancer growth

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's defenses can swoop in, destroying rogue cells before they can do much damage. Lying at the heart of this early warning system are lipids, fatty compounds previously seen by cancer biologists primarily as a fuel source for burgeoning tumors.

18 Sep 2024

Genetic analysis challenges the idea that loneliness directly causes diseases

Research reveals that loneliness is linked to numerous diseases observationally, but genetic analysis shows it's likely a marker rather than a cause.

18 Sep 2024

Air pollution drives higher Parkinson’s risk and worsens symptoms in affected patients

Higher air pollution levels, particularly PM2.5 and NO2, significantly increase the risk of Parkinson's disease and worsen clinical outcomes like dyskinesia.

17 Sep 2024

Genetic News and Research

Collaborative study offers hope for syphilis vaccine development

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

FIND Lp(a) machine learning model aims to transform cardiovascular disease screening

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

IBD increases type 1 diabetes risk, revealing a bidirectional link between the two conditions

Early intervention key for mental health in children with cystic fibrosis

New biomarkers offer hope for early detection and prevention of Alzheimer's

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Leptin variations may influence brain health and dementia development

New tool unveils dynamic changes in brain extracellular matrix

Study helps explain why having ApoE4 increases risk of neurodegeneration

Scientists pinpoint thousands of gene variants linked to breast and ovarian cancer risk

Exposure to styrene and ethylbenzene elevates diabetes risk

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Genome-wide association study identifies genetic risk factors for dementia

Lipid molecule fuels cancer growth

Genetic analysis challenges the idea that loneliness directly causes diseases

Air pollution drives higher Parkinson’s risk and worsens symptoms in affected patients

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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