Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Concert Pharmaceuticals announces 2013 year-end results; posts record revenue of $25.4M

Concert Pharmaceuticals, Inc. today reported financial results for the year ended December 31, 2013 and provided an update on corporate activities.

31 Mar 2014

Researchers quantify proportion of adults potentially affected by updated 2014 BP recommendations

Applying the updated 2014 blood pressure (BP) guideline to the U.S. population suggests that nearly 6 million adults are no longer classified as needing hypertension medication, and that an estimated 13.5 million adults would now be considered as having achieved goal blood pressure, primarily older adults, according to a JAMA study released online to coincide with the 2014 American College of Cardiology Scientific Sessions.

31 Mar 2014

Aleglitazar drug does not reduce risk of cardiovascular events in patients with type 2 diabetes

Use of the drug aleglitazar, which has shown the ability to lower glucose levels and have favorable effects on cholesterol, did not reduce the risk of cardiovascular death, heart attack or stroke among patients with type 2 diabetes and recent heart attack or unstable angina, according to a JAMA study released online to coincide with presentation at the 2014 American College of Cardiology Scientific Sessions.

31 Mar 2014

Millions of US adults may no longer need blood pressure medication, study suggests

New guidelines that ease the recommended blood pressure could result in 5.8 million U.S. adults no longer needing hypertension medication, according to an analysis by Duke Medicine researchers.

31 Mar 2014

Cartoons could help educate, empower patients to cope better with chronic conditions

Researchers from the University of Southampton have shown that cartoons could be a beneficial way of educating patients and empowering them to cope better with their long term conditions.

29 Mar 2014

ATHENA develops surrogate organ system for toxicity testing

Creating surrogate human organs, coupled with insights from highly sensitive mass spectrometry technologies, a new project is on the brink of revolutionizing the way we screen new drugs and toxic agents.

29 Mar 2014

Tumor suppressor gene linked to stem cell function

Just as archeologists try to decipher ancient tablets to discern their meaning, UT Southwestern Medical Center cancer biologists are working to decode the purpose of an ancient gene considered one of the most important in cancer research.

27 Mar 2014

Research: Mediterranean diet linked to lower risk of diabetes

Adoption of a Mediterranean diet is linked to a lower risk of diabetes, especially among people at high risk for cardiovascular disease, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

27 Mar 2014

Vancouver-led research initiative awarded $1.5M grant to prevent deaths of moms and babies

A Vancouver-led research initiative to prevent deaths of moms and babies got a boost recently with a new $1.5-million grant from the Bill & Melinda Gates Foundation. The grant will expand efforts to improve diagnosis and care for pregnant women with pre-eclampsia.

27 Mar 2014

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Infectious disease specialists at the Johns Hopkins Children's Center have identified a protein that regulates the body's immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune systems.

27 Mar 2014

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

The international guidelines on the drug-based therapy of diabetes mellitus specify which factors need to be taken into account during treatment.

27 Mar 2014

FMCNA introduces newly branded Frenova Renal Research business

Fresenius Medical Care North America, the world's largest provider of dialysis services, today introduced its newly branded Frenova Renal Research business, the only Phase I-IV drug and device clinical development partner dedicated exclusively to renal research.

26 Mar 2014

Researchers explore link between diet, metabolic homeostasis and air pollutant exposure

Is air pollution connected with increases in obesity, diabetes, and chronic kidney disease? Researchers are providing insight into that question today at the Society of Toxicology 53rd Annual Meeting and ToxExpo in Phoenix, Ariz.

26 Mar 2014

Study lays groundwork for PET imaging studies on human Menkes disease

Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This study lays the groundwork for PET imaging studies on human Menkes disease patients to identify new therapy options.

26 Mar 2014

AM-Pharma reports positive results from recAP Phase I trial for Acute Kidney Injury

AM-Pharma B.V., a biopharmaceutical company focused on the development of recAP (recombinant human Alkaline Phosphatase) for inflammatory indications, announces the results of its Phase I trial with both single and multiple ascending doses, which demonstrate that recAP is safe and well tolerated at all doses.

26 Mar 2014

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

ZS Pharma, a specialty pharmaceutical company developing novel treatments for kidney, cardiovascular and liver disorders, today announced that it has begun enrolling patients in ZS004, its second Phase 3 clinical trial of ZS-9, a novel investigational treatment for hyperkalemia.

25 Mar 2014

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

In recognition of Kidney Health Awareness Month, Renal Ventures Management, LLC (RVM), a leading provider of dialysis services for patients suffering from chronic kidney failure, has published its first cookbook of kidney friendly recipes for it renal patients and their families.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

Otsuka obtains regulatory approval in Japan for pharmacological treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. today announced it has become the first company in the world to obtain regulatory approval for a pharmacological treatment of autosomal dominant polycystic kidney disease (ADPKD). Samsca (generic name: tolvaptan) has been approved in Japan in 7.5-mg and 15-mg tablet forms for extended use for the additional indication of ADPKD. Also, the new dosage form of 30-mg Samsca tablets has received approval for the indication of ADPKD.

24 Mar 2014

Investigators find group of drugs to treat heart attacks and cancer metastasis

Massachusetts General Hospital (MGH) investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.

24 Mar 2014

Nephrology News and Research

Further Reading

Concert Pharmaceuticals announces 2013 year-end results; posts record revenue of $25.4M

Researchers quantify proportion of adults potentially affected by updated 2014 BP recommendations

Aleglitazar drug does not reduce risk of cardiovascular events in patients with type 2 diabetes

Millions of US adults may no longer need blood pressure medication, study suggests

Cartoons could help educate, empower patients to cope better with chronic conditions

ATHENA develops surrogate organ system for toxicity testing

Tumor suppressor gene linked to stem cell function

Research: Mediterranean diet linked to lower risk of diabetes

Vancouver-led research initiative awarded $1.5M grant to prevent deaths of moms and babies

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Expert highlights the importance of gender-specific approach for treating diabetes mellitus

FMCNA introduces newly branded Frenova Renal Research business

Researchers explore link between diet, metabolic homeostasis and air pollutant exposure

Study lays groundwork for PET imaging studies on human Menkes disease

AM-Pharma reports positive results from recAP Phase I trial for Acute Kidney Injury

ZS Pharma starts patient enrollment in ZS-9 Phase 3 trial for treatment of hyperkalemia

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

Otsuka obtains regulatory approval in Japan for pharmacological treatment of ADPKD

Investigators find group of drugs to treat heart attacks and cancer metastasis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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