Therapeutics News and Research

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Study shows how loss of glial protein drives brain development dysfunction

When we think of the brain, we think of neurons. But much of the brain is made of non-neuronal cells called glial cells, which help regulate brain development and function.

25 Jun 2021

WEHI collaborates with Boehringer Ingelheim to develop novel anti-cancer therapeutics

WEHI has partnered with Boehringer Ingelheim, a leading research-driven pharmaceutical company, in a collaboration to discover and develop anti-cancer therapeutics using a promising new technology called targeted protein degradation.

25 Jun 2021

Anti-inflammatory nanoparticles could be applied to the weakening muscles of DMD patients

Muscular dystrophies are a group of genetic diseases that lead to the progressive loss of muscle mass and function in patients, with the incurable Duchenne Muscular Dystrophy (DMD), which affects all the body's muscles primarily in boys, being particularly severe.

25 Jun 2021

New resource could make targeted cancer therapies more accessible for Australian patients

A new resource developed at the Garvan Institute of Medical Research and The Kinghorn Cancer Centre for oncologists could help make targeted cancer therapies more accessible for Australian patients.

25 Jun 2021

Study shows how SARS-CoV-2 virus enters cells to cause infection

Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection.

24 Jun 2021

City of Hope researchers identify how breast cancer cells acquire resistant traits

City of Hope, a world-renowned cancer research and treatment center, has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies, according to a new study published in Nature Cancer.

24 Jun 2021

Non-invasive technology shows potential to overcome detrimental effects of aging and dementia

Ultrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, Queensland Brain Institute researchers have found.

24 Jun 2021

New class of compounds can stop the reproduction of coronavirus

A human genetic mechanism hijacked by SARS-CoV-2, the coronavirus behind the COVID-19 pandemic, to help it spread also makes it vulnerable to a new class of drug candidates, a new study finds.

24 Jun 2021

Three CU researchers recognized for contributions to immunotherapy in childhood cancer

Three members of the University of Colorado Cancer Center and a longstanding supporter of the campus are part of a group of more than 200 researchers nationwide who were recognized in April with the Team Science Award from the American Association for Cancer Research.

23 Jun 2021

SARS-CoV-2 infection and transmission in the North American deer mouse

A recent study conducted in Canada reports that the North American deer mouse can be infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans.

23 Jun 2021

A study on hospitalized COVID-19 patients who received plasma therapy

A new study has been published which focuses on the evaluation of the outcomes of infected COVID-19 patients who were treated with CCP therapy.

23 Jun 2021

New study enrolls young adults to evaluate SARS-CoV-2 infection

The Prevent COVID U study, which launched in late March 2021 to evaluate SARS-CoV-2 infection and transmission among university students vaccinated with the Moderna COVID-19 Vaccine, has expanded beyond the university setting to enroll young adults ages 18 through 29 years and will now also include people in this age group who choose not to receive a vaccine.

23 Jun 2021

MMRI expert receives diversity grant for research on autism, heart disease

Does a connection exist between the development of heart disease and autism? That's a question Dr. Maria Kontaridis, Executive Director and Gordon K. Moe Professor at the Masonic Medical Research Institute (MMRI), and her team have been actively investigating thanks to a grant from the American Heart Association (AHA).

23 Jun 2021

Modulating the rap1 mechanism can help control blood sugar levels

Managing type 2 diabetes typically involves losing weight, exercise and medication, but new research by Dr. Makoto Fukuda and colleagues at Baylor College of Medicine and other institutions suggests that there may be other ways to control the condition through the brain.

23 Jun 2021

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

In a cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new discoveries.

22 Jun 2021

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

22 Jun 2021

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

The RDM Positive Impact Foundation is funding an ambitious $1.25 million research project at the UC Davis MIND Institute to study SYNGAP1.

22 Jun 2021

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

How do you kill tumor cells that can't be targeted? Get their more susceptible neighbors to help.

22 Jun 2021

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

A team of scientists from the Pennsylvania State University, USA, recently analyzed the pharmacodynamics and pharmacokinetics of antiviral drug remdesivir using computational models. Based on the study findings, which are yet to be peer-reviewed, the scientists recommend that for effective inhibition of SARS-CoV-2 infection, remdesivir should be used with other antiviral medicines, or its dosing regimen should be optimized to improve bioavailability.

22 Jun 2021

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

A review published in Phytotherapy Research discussed the natural anti-SARS-CoV-2 products identified based on in silico prediction. The review’s authors also illustrate the impact of many phytochemicals either alone or in combination with traditional treatments and their potential molecular mechanisms involved in SARS-CoV-2 prevention and treatment.

22 Jun 2021

Therapeutics News and Research

Study shows how loss of glial protein drives brain development dysfunction

WEHI collaborates with Boehringer Ingelheim to develop novel anti-cancer therapeutics

Anti-inflammatory nanoparticles could be applied to the weakening muscles of DMD patients

New resource could make targeted cancer therapies more accessible for Australian patients

Study shows how SARS-CoV-2 virus enters cells to cause infection

City of Hope researchers identify how breast cancer cells acquire resistant traits

Non-invasive technology shows potential to overcome detrimental effects of aging and dementia

New class of compounds can stop the reproduction of coronavirus

Three CU researchers recognized for contributions to immunotherapy in childhood cancer

SARS-CoV-2 infection and transmission in the North American deer mouse

A study on hospitalized COVID-19 patients who received plasma therapy

New study enrolls young adults to evaluate SARS-CoV-2 infection

MMRI expert receives diversity grant for research on autism, heart disease

Modulating the rap1 mechanism can help control blood sugar levels

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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