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Experimental drug APN01 prevents COVID-19 infection in the lab

With the world gripped with the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a frantic rush to find an effective drug that can be used to treat the disease.

6 Apr 2020

Analysis of causative protein genotype can help predict Alport syndrome severity

A Japanese research team has successfully developed a system to predict the severity of Alport syndrome, a serious hereditary kidney disease that occurs in about 1 out of 5,000 people in the US. Patients with Alport syndrome have abnormalities in the causative protein, type IV collagen, that often lead to chronic renal dysfunction requiring dialysis.

6 Apr 2020

Long-standing racial and income disparities seen creeping into COVID-19 care

The new coronavirus doesn’t discriminate. But physicians in public health and on the front lines said they already can see the emergence of familiar patterns of racial and economic bias in the response to the pandemic.

6 Apr 2020

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

5 Apr 2020

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

A new study from Columbia University Irving Medical Center and the Herbert Irving Comprehensive Cancer Center suggests a compound in development for a rare kidney stone disease may have potential against pancreatic cancer.

2 Apr 2020

Extracellular forces regulate the formation of epithelia-integrating actomyosin bundles

Different surfaces and organs of the body are covered by epithelial tissue, which is composed of cells tightly connected to each other.

2 Apr 2020

Pancreatitis drug Nafamostat shows promise for coronavirus

With the increasing number of infections across the globe, scientists have resorted to studying existing drugs in the hope of discovering a cure for the coronavirus disease (COVID-19). A team of researchers has found that an existing drug, Nafamostat or Fusan, a drug used to treat acute pancreatitis, may effectively block the process used by the novel coronavirus to spread and cause illness.

1 Apr 2020

Antihypertensive drugs may protect against COVID-19 in heart patients

Common drugs used in high blood pressure, heart failure, and diabetic patients with kidney damage, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), could be protective in patients with COVID-19.

31 Mar 2020

Two newer types of diabetes medications show heart and kidney benefits

Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

Her genetic test revealed a microscopic problem — and a jumbo price tag

Michelle Kuppersmith, 32, feels great, works full time and exercises three to four times a week. So she was surprised when a routine blood test found that her body was making too many platelets, which help control bleeding.

31 Mar 2020

Should you bring mom home from assisted living during the pandemic?

Dr. Alison Webb took her 81-year-old father out of assisted living, to live.

31 Mar 2020

More than 5,000 surgery centers can now serve as makeshift hospitals during COVID-19 crisis

The Trump administration cleared the way Monday to immediately use outpatient surgery centers, inpatient rehabilitation hospitals, hotels and even dormitories as makeshift hospitals, health care centers or quarantine sites during the coronavirus crisis.

30 Mar 2020

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Overuse injuries - think muscle strains, tennis elbow, and rotator cuff tears - are a considerable problem in the United States, especially among young athletes.

30 Mar 2020

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too low.

30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Weakness in lung and kidney cancer cells could serve as therapeutic target

An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments.

30 Mar 2020

Renal denervation effective in patients with untreated high blood pressure

Three months after undergoing renal denervation —a procedure that delivers energy to overactive nerves leading to the kidney to decrease their activity—patients with untreated high blood pressure had statistically significant reductions in average blood pressure over 24 hours compared with patients who underwent a sham procedure and experienced no major adverse effects, according to results from the SPYRAL-HTN OFF MED pivotal trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio.

27 Mar 2020

Heart and kidney patients should keep taking their medicines during COVID-19 pandemic

As the COVID-19 pandemic unfolds, inaccurate medical information has flooded social media and other channels.

27 Mar 2020

Protect the lives of healthcare workers fighting against disease outbreaks

Protect healthcare workers from dying from disease outbreaks while in the line of duty, urges Ifeanyi M. Nsofor. The continuing Coronavirus (COVID-19) outbreak is a reminder that healthcare workers are in the line of fire when responding to infectious disease outbreaks and we must ensure that they are protected.

27 Mar 2020

Kidney News and Research

Experimental drug APN01 prevents COVID-19 infection in the lab

Analysis of causative protein genotype can help predict Alport syndrome severity

Long-standing racial and income disparities seen creeping into COVID-19 care

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Starving pancreatic cancer cells of cysteine may induce tumor ferroptosis

Extracellular forces regulate the formation of epithelia-integrating actomyosin bundles

Pancreatitis drug Nafamostat shows promise for coronavirus

Antihypertensive drugs may protect against COVID-19 in heart patients

Two newer types of diabetes medications show heart and kidney benefits

Her genetic test revealed a microscopic problem — and a jumbo price tag

Should you bring mom home from assisted living during the pandemic?

More than 5,000 surgery centers can now serve as makeshift hospitals during COVID-19 crisis

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

Research could open up new therapeutic strategies for some lung and kidney cancers

Weakness in lung and kidney cancer cells could serve as therapeutic target

Renal denervation effective in patients with untreated high blood pressure

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Heart and kidney patients should keep taking their medicines during COVID-19 pandemic

Protect the lives of healthcare workers fighting against disease outbreaks

Event guide: 8th CKD Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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