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Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Study reveals mechanism of a previously unexplained type of cell death

A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for novel cancer therapeutic strategies.

6 Feb 2023

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Researchers explored the association between the human microbiome and improved renal cell carcinoma outcomes.

6 Feb 2023

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Researchers explored the impact of biological interventions in reducing cardiovascular risk among psoriasis patients.

6 Feb 2023

New type of immunotherapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

MIT study helps shed light on why the immune system mounts a dull response to lung cancer

Immunotherapy - drug treatment that stimulates the immune system to attack tumors - works well against some types of cancer, but it has shown mixed success against lung cancer.

3 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

New therapeutic vaccine based on an allogeneic Plasmacytoid DC cell line

A new research perspective was published in Genes & Cancer on January 30, 2023, entitled, "Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines."

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

New device identifies key membrane protein in urine that could be used to detect brain cancer

Researchers at Nagoya University in Japan have used a new device to identify a key membrane protein in urine that indicates whether the patient has a brain tumor.

2 Feb 2023

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

An unexpected discovery made by experts at the Brain Tumor Center at Cincinnati Children's while studying a rare-but-deadly type of brain tumor may also lead to improved treatments for several other forms of cancer that share a common influencing factor called a YAP fusion protein.

2 Feb 2023

Tumor News and Research

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Study reveals mechanism of a previously unexplained type of cell death

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

New type of immunotherapy effective in mice with ovarian cancer

MIT study helps shed light on why the immune system mounts a dull response to lung cancer

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

New therapeutic vaccine based on an allogeneic Plasmacytoid DC cell line

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

Improving CAR-based-immunotherapies using a molecular anchor

New device identifies key membrane protein in urine that could be used to detect brain cancer

Unexpected discovery may lead to improved treatments for YAP fusion-driven cancers

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Research reveals a candidate drug and biomarker to target uveal melanoma

Researchers identify a gene that drives T lymphocytes to exhaustion

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Integrated model helps enhance patient care for pediatric brain tumors

Deep-learning based filter removes false positives, improves the accuracy of cancer diagnosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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