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Life Sciences Discovery Fund awards $2.2 million to support new solid-tumor research program

The state's Life Sciences Discovery fund has awarded $2.2 million to establish a formal phase 1 clinical-trials program to test new therapies for solid tumors at Fred Hutchinson Cancer Research Center. Announced this evening, the grant is among the first funded by Washington's $350 million tobacco-lawsuit-settlement bonus.

17 Apr 2008

Anti-cholinergic drugs may increase cognitive decline in older people

Anticholinergic drugs, such as medicines for stomach cramps, ulcers, motion sickness, and urinary incontinence, may cause older people to experience greater decline in their thinking skills than people not taking the drugs, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12–19, 2008.

17 Apr 2008

The mechanism of phosphorus as a cardiovascular risk factor in chronic kidney disease

The estimated 19 million Americans living with chronic kidney disease (CKD) face a high risk of death from cardiovascular disease. Recent studies have shown that a main source of this cardiovascular risk is CKD patients' high levels of blood phosphate.

17 Apr 2008

Yeast cells used to screen for potential Lou Gehrig's disease drugs

Researchers from the University of Pennsylvania School of Medicine are developing a novel approach to screen for drugs to combat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, using yeast cells.

17 Apr 2008

Study suggests that antidepressants could also be used for the treatment of amblyopia

In the April 18 issue of Science, scientists from the Scuola Normale Superiore in Pisa, Italy and the Neuroscience Centre at the University of Helsinki, Finland, provide new information about the mechanism of action of antidepressant drugs.

17 Apr 2008

Mistletoe therapy in oncology

For many people, mistletoe conjures up images of Christmas holidays, but in parts of Europe, mistletoe extract is widely used as a therapy for cancer patients. However, a new review of studies finds only weak evidence that the treatment provides any benefit.

17 Apr 2008

New molecule could be key to anti-heart attack drug

When too many blood platelets stick together in the bloodstream, they form dangerous clots that can clog blood vessels and cause a heart attack. If a clot doesn't get dissolved or rapidly removed, it can cause permanent damage or even death.

17 Apr 2008

Unbiased, comprehensive analysis of drug research from new web site

Physicians and consumers who want fair and balanced information about the most appropriate uses for prescription medications can now find it using a Web-based resource that provides easily accessible, science-based research about drug uses free from pharmaceutical industry influence.

17 Apr 2008

Study shows factors influencing premature infant survival, disability

Based on observations of more than 4,000 infants, researchers in an NIH newborn research network have identified several factors that influence an extremely low birth weight infant's chances for survival and disability. The findings offer new information to physicians and families considering the most appropriate treatment options for this category of infants.

17 Apr 2008

New type of drug shrinks primary breast cancer tumours significantly in just six weeks

A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6) (Thursday 17 April).

17 Apr 2008

Discovery of critical detail of cellular defense against genetic mistakes

Researchers are closing in on a completed diagram of how human cells protect themselves against constant genetic mistakes that contribute to most diseases, according to a study to be published in the April 18 edition of the journal Cell.

17 Apr 2008

Mushroom extract could stop breast cancer cell growth

Mushroom extracts could halt the growth of breast cancer cells, suggests research published in the British Journal of Cancer.

17 Apr 2008

Drugs in the pipeline: new therapies that could change treatment strategies

The investigational drug AZD2171 (cediranib) may help shrink tumors and prolong survival of patients with a relatively common, aggressive type of brain cancer, according to results from a clinical trial conducted by Boston researchers.

16 Apr 2008

Antipsychotic drugs increase risk of developing pneumonia in elderly

Elderly patients who use antipsychotic drugs have a 60 percent increased risk of developing pneumonia compared to non-users.

16 Apr 2008

Two new clinical trials show promise for basal cell carcinoma and pancreatic cancer

Clinical researchers at Scottsdale Healthcare and TGen have announced the results of two clinical trials that show promise for patients battling cancer.

16 Apr 2008

Study details cost-effectiveness of rheumatoid arthritis treatments for Medicare recipients

For elderly and disabled rheumatoid arthritis (RA) sufferers, the Medicare Prescription Drug Improvement and Modernization Act (MMA) brought the promise of better disease management with "biologic" drugs.

15 Apr 2008

Statins may modestly reduce blood pressure

The medications known as statins, typically prescribed to lower blood cholesterol levels, may also modestly reduce blood pressure, according to a report in the April 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Apr 2008

Sleeping sickness metabolic 'fingerprint' could lead to earlier diagnosis

Sleeping sickness creates a metabolic 'fingerprint' in the blood and urine, which could enable a new test to be developed to diagnose the disease, according to new research published today in the journal Proceedings of the National Academy of Sciences.

15 Apr 2008

Scientists solve arsenic's cancer paradox

Cancer Research UK scientists have discovered how arsenic works as an effective treatment for leukaemia - according to a report in Nature Cell Biology.

15 Apr 2008

Potential blood test for chronic sinusitis identified

A protein profile has been identified in the blood of chronic sinusitis sufferers that may enable physicians to objectively diagnosis and treat the disease, researchers say.

15 Apr 2008