Gene Expression News and Research

RSS

Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Gene expression patterns could help predict treatment for breast cancer, research shows

A Michigan State University breast cancer researcher has shown that effective treatment options can be predicted based on the way certain breast cancer genes act or express themselves.

21 Feb 2017

New imaging technology catches DNA naturally fluorescing

Many of the secrets of cancer and other diseases lie in the cell's nucleus. But getting way down to that level -- to see and investigate the important genetic material housed there -- requires creative thinking and extremely powerful imaging techniques.

17 Feb 2017

UTMB researchers unravel mystery of how Zika virus causes birth defects

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered the mechanisms that the Zika virus uses to alter brain development. These findings are detailed in Stem Cell Reports.

17 Feb 2017

Researchers provide insight into causes of left or right-handedness

A preference for the left or the right hand might be traced back to that asymmetry. "These results fundamentally change our understanding of the cause of hemispheric asymmetries," conclude the authors. The team report about their study in the journal eLife.

17 Feb 2017

Discovery of 'molecular switch' could lead to effective new treatments for auto-immune diseases

The discovery of the 'molecular switch' that causes inflammatory bowel disease (IBD) and Celiac disease, could lead to more effective new treatments for these life-changing auto-immune conditions, according to research from scientists at King's College London and University College London.

16 Feb 2017

HMS scientists listen to crosstalk between gut microbes and immune system

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated in conditions ranging from inflammatory bowel disease to multiple sclerosis.

16 Feb 2017

UNIGE researchers develop new technique to improve diagnosis of genetic diseases

When a child is conceived, he or she receives DNA from both parents. The child's own genome thus consists of a maternal and a paternal genome. However, some genes — about 100 out of the 20,000 encoded genes— are exclusively expressed either from the maternal or from the paternal genome, with the other copy of the gene remaining silent.

16 Feb 2017

Signals from fat cells may aid in diagnostics for metabolic conditions

Fat cells are not simply big blobs of lipid quietly standingby in the body--instead, they send out hormones and other signaling proteins that affect many types of tissues.

15 Feb 2017

Scientists identify genetic signature of risk for type 2 diabetes

Why do some people get Type 2 diabetes, while others who live the same lifestyle never do? For decades, scientists have tried to solve this mystery - and have found more than 80 tiny DNA differences that seem to raise the risk of the disease in some people, or protect others from the damagingly high levels of blood sugar that are its hallmark.

14 Feb 2017

New RNAi treatment safely blocks ocular inflammation in mice

Scientists have developed a new RNA interference therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.

14 Feb 2017

Study discovers how gut bacteria interacts with microRNAs to promote colon cancer growth

Gut microbes can influence the growth of colon cancer, though little is known about how they trigger the disease.

14 Feb 2017

LMU study shows crucial role of microRNAs in protecting precursors of neurons

Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.

13 Feb 2017

Novel cell therapy may repair heart damage using modified cells from facial muscle

Researchers at the University of Cincinnati have received $2.4 million in federal funding to pursue research on a novel cell therapy that would repair heart damage using modified cells taken from the patient's own facial muscle.

8 Feb 2017

Scientists show how immune receptor activated by bacteria contributes to diabetic bladder dysfunction

Bladder dysfunction is a reality for about half of patients with diabetes and now scientists have evidence that an immune system receptor that's more typically activated by bacteria is a major contributor.

7 Feb 2017

Researchers evaluate biological effects of exposure to cigarette smoke versus e-cigarette aerosols

Researchers reported changes in the expression levels of 123 genes when reconstituted lung tissue was exposed to cigarette smoke, compared to only two genes that could be confirmed following exposure to e-cigarette aerosols.

6 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

Research unravels molecular mechanisms of antisense oligonucleotides

Stanley T. Crooke, MD, PhD, CEO of Ionis Pharmaceuticals and recipient of the 2016 Lifetime Achievement Award from the Oligonucleotide Therapeutic Society presents a detailed look at the mechanisms that underlie antisense drug activity in the article entitled "Molecular Mechanisms of Antisense Oligonucleotides," published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

2 Feb 2017

New study offers insights into how antidepressants work in the brain

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression.

2 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

TSRI study offers first look at early stages of brain development in patients with Fragile X syndrome

A new study led by scientists at The Scripps Research Institute is giving researchers a first look at the early stages of brain development in patients with Fragile X syndrome, a disorder that causes mild to severe intellectual disability and is the most common genetic cause of autism spectrum disorder.

31 Jan 2017