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Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

New study expands the knowledge on tumor-suppressor role of HERC proteins

The RAF protein could be a therapeutical target to treat the tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Institute for Biomedical Research.

20 Feb 2020

Finding new clues to combat glioblastoma

Glioblastoma is an aggressive, killer disease. While victims of this fast-moving brain tumor comprise only about 15% of all people with brain cancer, its victims rarely survive more than a few years after diagnosis.

20 Feb 2020

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

In 1900, German physician Paul Ehrlich came up with the notion of a "magic bullet." The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

19 Feb 2020

Study identifies new CoV responsible for the Wuhan outbreak

The 2019 novel coronavirus causes fatal pneumonia that has claimed over 1300 lives, with more than 52000 confirmed cases of infection by February 13, 2020, all in the span of just over a month.

18 Feb 2020

IU researcher identifies new genomic regions that increase skin cancer risk

An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer.

18 Feb 2020

Antioxidant in mushrooms may relieve symptoms of pre-eclampsia

Pregnancy hypertension, or Pre-eclampsia, is a complex disorder of pregnancy. Treatment of elevated blood pressure can manage the condition in the mother, but in severe cases delivery is needed, which can present a major problem to the baby if it is born prematurely.

18 Feb 2020

Study provides insight into link between cancer driver gene and alternative splicing changes

A multi-institutional group of researchers led by Children's Hospital of Philadelphia has linked a strong cancer driver gene to changes in proteins that regulate alternative splicing.

17 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Intratumoral heterogeneity linked to chemotherapy resistance in small-cell lung cancer

Small cell lung cancer accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes.

17 Feb 2020

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Scientists have created one of the most detailed maps of breast cancer ever achieved, revealing how genetic changes shape the physical tumor landscape, according to research funded by Cancer Research UK and published in Nature Cancer today (Monday).

17 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

Bile duct cancer treatment could be improved by tailored medication

Treatment of patients suffering from bile duct cancer could be improved by tailoring medication to the levels of a key protein in people with the disease, according to new research.

16 Feb 2020

New method to measure mutations in father's sperm may reveal ASD risk in future children

While the causes of autism spectrum disorder are not fully understood, researchers believe both genetics and environment play a role.

13 Feb 2020

Newly discovered large phages blur the life/non-life boundary

A new study published in the journal Nature shows that there are literally hundreds of viruses large enough to consume bacteria, and with properties that are typical of a living organism rather than the non-living self-replicating packages of DNA/RNA that viruses are often assumed to be.

12 Feb 2020

Researchers engineer probiotics to safely deliver immunotherapies to tumors

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors.

12 Feb 2020

Mysterious virus found in Brazil puzzles scientists with its unique genetic makeup

A team of Brazilian scientists discovered a puzzling new virus made of genetic material never seen before. But the virus won’t pose a serious health threat to humanity since it seems to only hunt amoebas.

12 Feb 2020

NETRF announces $3.5 million in research grants to improve neuroendocrine tumor treatment

The Neuroendocrine Tumor Research Foundation, Boston, MA, today announced $3.5 million in neuroendocrine tumor research grants to fund 12 projects around the world in pursuit of more precise treatments for this uncommon cancer affecting an estimated 171,000 Americans.

12 Feb 2020

Vapers exhibit similar chemical changes in their genome as smokers

Biologically important changes in DNA seen in smokers are also being found in people who vape, according to a new study published in the journal Epigenetics.

12 Feb 2020

DNA misfolding linked to heightened risk for Type 1 diabetes

It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome--about six feet of DNA--is compressed into the micrometer space of the nucleus via a three-dimensional folding process.

11 Feb 2020

Genomic News and Research

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

New study expands the knowledge on tumor-suppressor role of HERC proteins

Finding new clues to combat glioblastoma

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

Study identifies new CoV responsible for the Wuhan outbreak

IU researcher identifies new genomic regions that increase skin cancer risk

Antioxidant in mushrooms may relieve symptoms of pre-eclampsia

Study provides insight into link between cancer driver gene and alternative splicing changes

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

Intratumoral heterogeneity linked to chemotherapy resistance in small-cell lung cancer

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Generating genomes and encoding new abilities into artificial DNA

Bile duct cancer treatment could be improved by tailored medication

New method to measure mutations in father's sperm may reveal ASD risk in future children

Newly discovered large phages blur the life/non-life boundary

Researchers engineer probiotics to safely deliver immunotherapies to tumors

Mysterious virus found in Brazil puzzles scientists with its unique genetic makeup

NETRF announces $3.5 million in research grants to improve neuroendocrine tumor treatment

Vapers exhibit similar chemical changes in their genome as smokers

DNA misfolding linked to heightened risk for Type 1 diabetes

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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