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Second man cured of HIV

A London is now free of HIV/AIDS after a stem cell transplant therapy. This is the second such case after the first case of cured HIV in Berlin.

5 Mar 2019

New therapeutic approach for patients with pancreatic cancer

One-year survival is low among patients diagnosed with pancreatic cancer. Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have now come up with a potential new therapy for pancreatic cancer patients.

5 Mar 2019

British man with HIV becomes second person ever to enter remission

A man in Britain has become the second person in the world to be cleared of HIV after receiving a stem cell transplant from an HIV-resistant donor.

5 Mar 2019

Researchers identify first genetic defect linked to biliary atresia

A nationwide consortium of researchers has identified the first genetic defect linked to biliary atresia, a mysterious liver disease that is the leading cause for liver transplantation in children.

5 Mar 2019

New clinical genomic testing helps identify mutations that drive childhood melanoma

Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma.

5 Mar 2019

Research opens door to promising new treatment strategy for deadly brain tumor in children

A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma - the most deadly brain tumor in children.

4 Mar 2019

Research shows how common fungus gets the flexibility to live in different host environments

The fungus Candida albicans is found in the gastrointestinal tract of about half of healthy adults with little if any effect, yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS.

1 Mar 2019

Breakthrough chromosome imaging could aid in development of new treatments

Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.

28 Feb 2019

Scientists identify how cells make choice between various mechanisms to repair DNA

When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.

28 Feb 2019

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients.

27 Feb 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

New form of hereditary osteoporosis identified

A research group headed by Professor Outi Mäkitie, Unviersity of Helsinki, identified in families with childhood-onset osteoporosis disease-causing mutations in a gene that had previously not been connected with the skeletal system or osteoporosis.

25 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

23 Feb 2019

Breast cancer study: Family-history-based models perform better than non-family-history based models

A team of researchers led by Columbia University Mailman School of Public Health Professor Mary Beth Terry, PhD, evaluated four commonly used breast cancer prediction models and found that family-history-based models perform better than non-family-history based models, even for women at average or below-average risk of breast cancer.

22 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

New identified biomarker predicts patients who might benefit from HER2-targeted agents

In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy.

22 Feb 2019

New blood test detects genetic disorders in fetuses

Tel Aviv University researchers have developed a new blood test for genetic disorders that may allow parents to learn about the health of their baby as early as 11 weeks into pregnancy.

21 Feb 2019

Mutation News and Research

Second man cured of HIV

New therapeutic approach for patients with pancreatic cancer

British man with HIV becomes second person ever to enter remission

Researchers identify first genetic defect linked to biliary atresia

New clinical genomic testing helps identify mutations that drive childhood melanoma

Research opens door to promising new treatment strategy for deadly brain tumor in children

Research shows how common fungus gets the flexibility to live in different host environments

Breakthrough chromosome imaging could aid in development of new treatments

Scientists identify how cells make choice between various mechanisms to repair DNA

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Researchers discover new and rare skeletal disease

Scientists identify cause of devastating pediatric brain disorder

New form of hereditary osteoporosis identified

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

Breast cancer study: Family-history-based models perform better than non-family-history based models

New study finds how high-fat diets fuel colorectal cancer growth

New identified biomarker predicts patients who might benefit from HER2-targeted agents

New blood test detects genetic disorders in fetuses

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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