Efficacy News and Research

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Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

How could probiotics be used in the management of gingivitis and periodontitis?

New research explores how probiotic-based therapy in conjunction with established treatment regimens can be an effective approach for combating gingivitis and periodontitis.

28 Dec 2022

World Health Organization reports insufficient evidence to support syndromic screening for COVID-19

According to a scientific brief by the World Health Organization (WHO), there is insufficient information to implement syndromic COVID-19 testing for SARS-CoV-2 transmission prevention across land borders.

28 Dec 2022

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Improved targeting method personalizes MRI-guided HIFU for the treatment of tremor patients

UT Southwestern physicians have developed an improved targeting method, four-tract tractography, to personalize MRI-guided, high-intensity focused ultrasound (HIFU) used at UTSW to treat medication refractory tremor in essential tremor and tremor-dominant Parkinson's disease.

27 Dec 2022

Wafer-thin device could drastically alter the course of treatment for Type 1 diabetes

A quarter-sized device created at Houston Methodist could drastically alter the course of treatment for Type 1 diabetes, a chronic condition that impacts millions of Americans and does not have a cure.

27 Dec 2022

Neural electrical activity-based brain-computer interfaces for interacting with the human deep brain

Brain-Machine Interface (BMI, also known as Brain-Computer Interface) provides a new dimension for human to interact with machines and the environment.

27 Dec 2022

Direct oral anticoagulants more effective and cost-effective for treating cancer-associated thrombosis

Research conducted by UC Davis Comprehensive Cancer Center and the University of Cincinnati shows that direct oral anti-coagulant (DOAC) drugs are more effective and are more cost-effective than low molecular weight heparin (LMWH) for treating cancer-associated thrombosis (CAT).

27 Dec 2022

Novel bacterial therapy approach opens up new treatment options for lung cancer patients

Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving patients with very few options.

26 Dec 2022

Study reveals why some germinal centers persist for months rather than weeks

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities.

23 Dec 2022

New technology achieves 99.7% purity in sorting target cells in real-time

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences have proposed a new technology, called optical tweezer-assisted pool-screening and single-cell isolation (OPSI) system, which achieves 99.7% purity of sorting target cells, with all done in real-time.

23 Dec 2022

Simple Corsi-Rosenthal boxes can help reduce exposure to indoor air pollutants

A team of researchers from Brown University's School of Public Health, Brown's School of Engineering and Silent Spring Institute found that simple air filtration devices called Corsi-Rosenthal boxes are effective at reducing indoor air pollutants.

23 Dec 2022

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

A new study evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in Argentinian children when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron were predominant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Machine learning used to generate a new holistic model for coronary artery disease

A recent study published in the Lancet journal investigated whether a quantitative in-silico score for coronary artery disease (ISCAD), based on a machine learning model, can be used as a clinical marker to detect coronary artery disease.

21 Dec 2022

Efficacy News and Research

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

How could probiotics be used in the management of gingivitis and periodontitis?

World Health Organization reports insufficient evidence to support syndromic screening for COVID-19

Scientists explore synthesis of griffithsin in cell-free systems

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Improved targeting method personalizes MRI-guided HIFU for the treatment of tremor patients

Wafer-thin device could drastically alter the course of treatment for Type 1 diabetes

Neural electrical activity-based brain-computer interfaces for interacting with the human deep brain

Direct oral anticoagulants more effective and cost-effective for treating cancer-associated thrombosis

Novel bacterial therapy approach opens up new treatment options for lung cancer patients

Study reveals why some germinal centers persist for months rather than weeks

New technology achieves 99.7% purity in sorting target cells in real-time

Simple Corsi-Rosenthal boxes can help reduce exposure to indoor air pollutants

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Cystic fibrosis drug shows promise to treat pneumonia

Impact of epigenetics on the clinical management of cancer patients

Machine learning used to generate a new holistic model for coronary artery disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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