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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

The importance of accurate pipetting in biomedical laboratory work

In this interview, Stephanie Stursberg, Group Product Manager for pipetting platforms at INTEGRA Biosciences, talks to NewsMedical about the importance of accurate and efficient pipetting in biomedical laboratory work.

From INTEGRA Biosciences 2 Nov 2022

Molecular drug transporters could improve treatment of cancers and other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

High-throughput sequencing reveals structured olfactory neuron projections

Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses.

1 Nov 2022

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

Study expands breast cancer patient population that can benefit from PARP inhibitors

A drug approved to treat breast cancer patients with mutations in the BRCA1 or BRCA2 genes may also benefit people who have other genetic mutations.

31 Oct 2022

Ancient genomes shed light on previously unknown aspect of human evolution

The use of ancient DNA, including samples of human remains around 45,000 years old, has shed light on a previously unknown aspect of human evolution.

31 Oct 2022

Lower risk of colorectal cancer associated with dietary flavanone and anthocyanidin intake, according to new research

In a new study, researchers assessed the risk of colorectal cancer (CRC) with the intake of flavonoids.

31 Oct 2022

Study finds increased antioxidant activity in citrus honey

Citrus honey has an increased abundance of antioxidants in comparison to other standard types of honey, according to a new study by University of the West of Scotland (UWS).

31 Oct 2022

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

This study is led by Dr. Na Yang (State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai University), and Dr. Bing Zhu (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Science).

28 Oct 2022

Faulty gene may explain why some people gain excessive weight despite normal food intake

A faulty gene, rather than a faulty diet, may explain why some people gain excessive weight even when they don't eat more than others, UT Southwestern researchers at the Center for the Genetics of Host Defense have discovered.

28 Oct 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

28 Oct 2022

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

28 Oct 2022

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

DNA News and Research

Further Reading

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

The importance of accurate pipetting in biomedical laboratory work

Molecular drug transporters could improve treatment of cancers and other diseases

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

High-throughput sequencing reveals structured olfactory neuron projections

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Study expands breast cancer patient population that can benefit from PARP inhibitors

Ancient genomes shed light on previously unknown aspect of human evolution

Lower risk of colorectal cancer associated with dietary flavanone and anthocyanidin intake, according to new research

Study finds increased antioxidant activity in citrus honey

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

Faulty gene may explain why some people gain excessive weight despite normal food intake

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

The epigenetic alterations of monocytes in severe COVID-19

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

Yeast reveals a key mechanism in how genes are controlled

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