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Researchers uncover first spontaneous animal model of human hypophosphatasia

A research group led by Professor Hannes Lohi at the University of Helsinki and Folkhälsan Research Center has uncovered a new skeletal disease in dogs.

30 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019

EZH2 mutations can be used as marker for diagnosing different types of cancers

Inside the cell, DNA is tightly wrapped around proteins and packed in a complex, 3D structure that we call "chromatin".

29 Jan 2019

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.

29 Jan 2019

NIH researchers discover that anti-flu antibodies can inhibit two different viral proteins

Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second viral protein in addition to the one that they bind.

25 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Novel therapeutic approach for treatment of leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia.

24 Jan 2019

Identical twins shine new light on genetic cause of juvenile arthritis

Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease.

24 Jan 2019

Cancer Research UK announces £60 million funding to tackle global cancer challenges

Cancer Research UK announced today that it is funding three major new international research initiatives on the microbiome, chronic inflammation and why some cancers are specific to certain tissues and not others.

23 Jan 2019

New research reveals mechanisms underlying the diversification of sex pheromones

Many organisms including insects, amphibians and yeasts use sex pheromones for attracting individuals of the opposite sex, but what happens to sex pheromones as new species emerge?

23 Jan 2019

Top institutions in the U.S. win Cancer Research UK's Grand Challenge competition

The U.S. will lead three new global research projects, tackling some of the biggest challenges in cancer research, it was announced today by Cancer Research UK.

23 Jan 2019

New approach to reduce toxic protein production in ALS

Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72.

22 Jan 2019

Mouse studies challenge 'inhibition' theory of autism

A detailed study of four mouse models of autism challenges the most common assumption about what goes wrong in brain circuits to cause disease symptoms.

21 Jan 2019

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany.

21 Jan 2019

Study shows hereditary hemochromatosis behind many cancers and joint diseases

A British study has found that “stealth disease”, also known as hemochromatosis, could be the reason behind several disease conditions including cancers and joint diseases.

20 Jan 2019

QIAGEN receives first companion diagnostic approval in Japan

QIAGEN N.V. today announced that the Japanese Pharmaceuticals and Medical Device Agency has approved the therascreen EGFR RGQ PCR Kit to allow its use as a companion diagnostic with Pfizer's VIZIMPRO (dacomitinib) for EGFR gene mutation-positive, inoperable or recurrent non-small cell lung cancer.

17 Jan 2019

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

Cocaine is a highly addictive psychostimulant that induces complex molecular, cellular and behavioral responses. Despite various approaches and years of pre-clinical studies, effective, mechanism-based therapies to assist with cocaine misuse and dependence are still sorely lacking.

16 Jan 2019

Researchers demonstrate how manganese produces parkinsonian syndrome

Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucléaires de Bordeaux Gradignan have demonstrated the consequences of a mutation responsible for a hereditary parkinsonian syndrome: accumulated manganese in the cells appears to disturb protein transport.

16 Jan 2019

Truncal mutations study suggests new direction in origins of cancer

Cancers most commonly arise because of a series of two to five mutations in different genes that combine to cause a tumor.

16 Jan 2019

Mutation News and Research

Researchers uncover first spontaneous animal model of human hypophosphatasia

New drug compounds show promise in treating acute myeloid leukemia

EZH2 mutations can be used as marker for diagnosing different types of cancers

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

NIH researchers discover that anti-flu antibodies can inhibit two different viral proteins

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Novel therapeutic approach for treatment of leukemia

Identical twins shine new light on genetic cause of juvenile arthritis

Cancer Research UK announces £60 million funding to tackle global cancer challenges

New research reveals mechanisms underlying the diversification of sex pheromones

Top institutions in the U.S. win Cancer Research UK's Grand Challenge competition

New approach to reduce toxic protein production in ALS

Mouse studies challenge 'inhibition' theory of autism

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

Study shows hereditary hemochromatosis behind many cancers and joint diseases

QIAGEN receives first companion diagnostic approval in Japan

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

Researchers demonstrate how manganese produces parkinsonian syndrome

Truncal mutations study suggests new direction in origins of cancer

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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