Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Multidimensional regulation of stem cell fate by the cohesin complex

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.

10 Oct 2025

Researchers identify key role of lactylation in driving aortic dissection

Recently, a research team led by Professor Jian-Xun Wang and Professor Tao Yu from Qingdao University made a significant breakthrough in understanding the role of lactylation modification in aortic dissection (AD).

10 Oct 2025

A blood test breakthrough for detecting heart damage from cancer therapy

Treatments for cancer are continuously improving, but they can still cause debilitating, even fatal, side effects.

10 Oct 2025

Discovery of unique brain cells sheds light on progressive multiple sclerosis

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease.

10 Oct 2025

Takara Bio USA, Inc. announces a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology

Takara Bio USA, Inc. ("Takara Bio USA"), a wholly owned subsidiary of Takara Bio Inc. ("Takara Bio"), today announced a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology.

9 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

Largest study of African American brain tissue reveals key Alzheimer gene activity

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S.

8 Oct 2025

Deregulated miR-145 and miR-27b impact adipogenesis in Hutchinson-Gilford progeria syndrome

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025, titled, "Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis."

7 Oct 2025

Paternal exercise enhances offspring endurance through sperm microRNAs

In a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

6 Oct 2025

Elderberry juice boosts key genes for metabolic flexibility in overweight adults

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight adults during meal challenges.

3 Oct 2025

Study uncovers cerebellar involvement and social impairment

Spinal muscular atrophy is a rare genetic disease of the nerve cells in the spinal cord that can appear as early as infancy. The disease leads to a progressive loss of muscle strength. Those affected often suffer from muscle weakness early on, as well as difficulties with movement, breathing, and swallowing.

3 Oct 2025

Second round of exercise boosts muscle growth in mice

New research offers potential good news for those who've lapsed at the gym. The study found that mice that voluntarily ran on an exercise wheel for four weeks, stopped for four weeks and ran again for another four weeks saw unexpected gains.

2 Oct 2025

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, which are closely associated with various diseases including neurodegenerative diseases and cancers.

30 Sep 2025

Study points toward earlier and more accurate detection of ALS

A new study applying multi-omics techniques and machine learning identified 33 plasma proteins that differ significantly in patients with amyotrophic lateral sclerosis (ALS).

29 Sep 2025

Gene expression test identifies prostate cancer patients who benefit from hormone therapy

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the first predictive biomarker in this setting.

29 Sep 2025

Genetic testing guides personalized radiation patients with HPV-positive throat cancer

Genetic testing can identify patients with HPV-positive throat cancer who may benefit from lower radiation doses, according to Cleveland Clinic research.

26 Sep 2025

Lysosomal activity in worms linked to transgenerational extension of lifespan

In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend the worm's life by up to 60 percent.

25 Sep 2025

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

25 Sep 2025

Lifespan study reveals age-specific biological changes in Down Syndrome

In a groundbreaking new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz discovered important differences in the physiological changes observed in over 300 individuals with Down syndrome across the lifespan.

24 Sep 2025

Reversing age-related vision loss with retinal lipid therapy

Changes in vision are often a common sign of aging. If you sit in a dimly lit restaurant with anyone over the age of 60, you'll likely hear the person say, "Hold on - let me pull out my cell phone. I need more light to read the menu!" But what if we could reverse age-related visual decline?

24 Sep 2025