Platelets News and Research

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Blood clot discovery could lead to development of better treatments for blood diseases

Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.

15 Feb 2019

New reversible antiplatelet therapy could reduce risk of blood clots, prevent cancer metastasis

A new reversible, drug-free antiplatelet therapy could reduce the risk of blood clots and potentially prevent cancer metastasis, according to a study published today in Science Translational Medicine.

14 Feb 2019

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes.

11 Feb 2019

New findings could provide novel approach to target and destroy cancer cells

An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers.

11 Feb 2019

Protein CDK6 appears to be key factor in influencing development of MPN

MPNs are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets.

6 Feb 2019

Study: Rutin found in fruits and vegetables protect mice against snake venom

Rutin, a bioflavonoid found in certain vegetables and fruits, protects mice against snake venom by minimizing bleeding and inflammation, according to a study performed at the Butantan Institute, a research institution belonging to the government of São Paulo State in Brazil.

9 Jan 2019

USC research could lay foundation for a vaccine against tick-borne virus

Two groundbreaking discoveries by USC researchers could lead to medications and a vaccine to treat or prevent a hemorrhagic fever transmitted by a new tick species before it spreads across the United States.

7 Jan 2019

FDA approves new treatment for rare disease of the bone marrow and blood

The U.S. Food and Drug Administration today approved Elzonris (tagraxofusp-erzs) infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of age and older.

21 Dec 2018

"Miracle" baby survives Ebola in Congo and rapid a new Ebola detection device

A female baby was diagnosed with the deadly Ebola when she was only six days old. According to the health officials in the Democratic Republic of the Congo (DRC), she seemed to have miraculously recovered from the viral infection.

17 Dec 2018

People who eat red meat have high levels of chemical associated with heart disease, study finds

Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide, that also is linked to heart disease.

11 Dec 2018

Platelets grown from stem cells could reduce the reliance on donated platelets

Researchers have developed a way to grow human platelets in the laboratory from stem cells derived from fat tissue. The achievement, reported today in the journal Blood, suggests manufactured platelets could eventually reduce the reliance on donated platelets to help patients with cancer and other disorders.

29 Nov 2018

Pitt research team explores whether 'active wrinkles' may help improve synthetic graft design

During a coronary bypass procedure, surgeons redirect blood flow using an autologous bypass graft, most often derived from the patient's own veins. However, in certain situations where the patient does not have a suitable vein, surgeons must rely on synthetic vascular grafts which, while life-saving, are more prone to clot formation that eventually obstructs the graft.

28 Nov 2018

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Two recent studies find advances in radiation therapy are helping to prolong or improve the lives of people with anal cancer, including those whose cancer has advanced to stage IV.

8 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins.

31 Oct 2018

MIT researchers devise way to help blood cells regenerate after radiation therapy

Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment, patients are vulnerable to infection and fatigue until new blood cells grow back.

24 Oct 2018

Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced detailed overall survival data from the PALOMA-3 trial, which evaluated IBRANCE (palbociclib) in combination with fulvestrant compared to placebo plus fulvestrant in women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer whose disease progressed on or after prior endocrine therapy.

22 Oct 2018

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients

Epigenetic therapy with histone deacetylase inhibitors is worth pursuing in hormone receptor positive advanced breast cancer, suggests a phase III trial reported today at the ESMO 2018 Congress in Munich.

22 Oct 2018

Platelets News and Research

Blood clot discovery could lead to development of better treatments for blood diseases

New reversible antiplatelet therapy could reduce risk of blood clots, prevent cancer metastasis

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

New findings could provide novel approach to target and destroy cancer cells

Protein CDK6 appears to be key factor in influencing development of MPN

Study: Rutin found in fruits and vegetables protect mice against snake venom

USC research could lay foundation for a vaccine against tick-borne virus

FDA approves new treatment for rare disease of the bone marrow and blood

"Miracle" baby survives Ebola in Congo and rapid a new Ebola detection device

People who eat red meat have high levels of chemical associated with heart disease, study finds

Platelets grown from stem cells could reduce the reliance on donated platelets

Pitt research team explores whether 'active wrinkles' may help improve synthetic graft design

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

CNIO researchers link MASTL protein to origin of thrombocytopenia

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

MIT researchers devise way to help blood cells regenerate after radiation therapy

Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients

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