Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Combination treatment can reduce tumor's resistance to chemotherapy in ovarian cancer

Treating ovarian cancer with platinum-based chemotherapy drugs such as cisplatin is initially very effective, with about four out of five patients responding favorably. However, most of these patients quickly become resistant to chemotherapy and may not respond as well to this standard treatment for the disease.

1 Nov 2016

Researchers identify protein linked to negative effects of senescence

Cellular senescence is a state in which normal healthy cells do not have the ability to divide. Senescence can occur when cancer-causing genes are activated in normal cells or when chemotherapy is used on cancer cells.

1 Nov 2016

Study identifies potential pathway to improve rate at which the body burns calories

Researchers say they have identified a potential pathway in our muscle tissue to improve the rate at which our bodies burn calories.

1 Nov 2016

UCI study reveals molecular activity behind electroacupunture's hypertension-lowering benefits

Researchers with the UCI Susan Samueli Center for Integrative Medicine have found that regular electroacupunture treatment can lower hypertension by increasing the release of a kind of opioid in the brainstem region that controls blood pressure.

31 Oct 2016

Myriad Genetics presents research data that validates accuracy of myPath Melanoma test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced it will present two new studies at the American Society of Dermatopathology (ASDP) annual meeting being held Oct. 27-30, 2016 in Chicago, Ill.

31 Oct 2016

Allen Institute for Brain Science maps the mouse cortex in 3-D

The Allen Institute for Brain Science has completed the three-dimensional mapping of the mouse cortex as part of the Allen Mouse Common Coordinate Framework (CCF): a standardized spatial coordinate system for comparing many types of data on the brain from the suite of Allen Brain Atlas resources.

27 Oct 2016

Scientists identify commonly affected genes sets among people with three mental disorders

Studying brain tissue from deceased donors, Johns Hopkins scientists have found common groups of genes disrupted among people with schizophrenia, bipolar disorder and major depression.

26 Oct 2016

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

A project led by the Spanish National Research Council (CSIC) researcher, Alejandro Toledo-Arana, at the Institute of Agro biotechnology (a centre shared between CSIC, the Public University of Navarra and The Regional Government of Navarra), is studying new genetic regulatory mechanisms in pathogenic bacteria.

26 Oct 2016

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, asthma, cancer, diabetes, heart disease and even mental illness.

24 Oct 2016

UGA researchers developing big data methods to help tackle diseases

The University of Georgia's Ping Ma will use a new grant to crunch big data numbers, not uncommon for a statistics professor. What is unusual is that his work may help save lives.

24 Oct 2016

Choline deficiency in sows during pregnancy impacts nutrient composition of milk

Choline is an essential nutrient that is used by the body in a number of ways. However, nearly 90 percent of adults do not get the recommended amount in their diets.

24 Oct 2016

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer.

21 Oct 2016

Novel approach may speed up development of new drugs against skin disease

In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them.

21 Oct 2016

Network of proteins linked to cancer may play vital role in male fertility

Researchers studying reproductive science identified a network of proteins often linked to cancer as also important to male fertility and the birth of healthy offspring, according to a study in the Oct. 18 online issue of Cell Reports.

19 Oct 2016

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

A molecular signaling pathway identified by an international research team could be the basis of improved treatment for osteoporosis.

19 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published October 14th, 2016 in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

17 Oct 2016

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Leukemia is a disease in which each cell can exhibit different genetic traits, and now Swedish researchers have found a cheap way to examine the individual cells. Reported in Nature Communications, the breakthrough could transform leukemia treatment.

14 Oct 2016

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient's quality of life and is notoriously hard to treat successfully, in part because its course and severity vary so much from one case to the next.

14 Oct 2016

Study provides insights into how species adapt to changing environments over many generations

Research led by the European Bioinformatics Institute and the University of Washington has shown that the biological diversity needed for evolution can be generated by changes in protein modifications.

14 Oct 2016

Gene Expression News and Research

Further Reading

Combination treatment can reduce tumor's resistance to chemotherapy in ovarian cancer

Researchers identify protein linked to negative effects of senescence

Study identifies potential pathway to improve rate at which the body burns calories

UCI study reveals molecular activity behind electroacupunture's hypertension-lowering benefits

Myriad Genetics presents research data that validates accuracy of myPath Melanoma test

Allen Institute for Brain Science maps the mouse cortex in 3-D

Scientists identify commonly affected genes sets among people with three mental disorders

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

UGA researchers developing big data methods to help tackle diseases

Choline deficiency in sows during pregnancy impacts nutrient composition of milk

New oncogene may contribute to high incidence of prostate cancer among African American men

Novel approach may speed up development of new drugs against skin disease

Network of proteins linked to cancer may play vital role in male fertility

Molecular signaling pathway could be basis of potential new treatment for osteoporosis

Penn researchers identify new immune system mechanism to fight against infections

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Crohn's disease appears to have two distinct genetic subtypes, study finds

Study provides insights into how species adapt to changing environments over many generations

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