Oxygen News and Research

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Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects more than 3.5 million people in the United States.

22 Aug 2018

Wyss researchers create model of the BBB-brain interface using microfluidically linked Organ Chips

The human brain, with its 100 billion neurons that control every thought, word, and action, is the most complex and delicate organ in the body. Because it needs extra protection from toxins and other harmful substances, the blood vessels that supply the brain with oxygen and nutrients are highly selective about which molecules can cross from the blood into the brain and vice versa.

22 Aug 2018

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you - or your dog?

21 Aug 2018

Researchers raise serious concerns about the accuracy of two baby monitors

Researchers who tested two commercially available baby monitors are raising serious concerns about the accuracy of these products, which are marketed to parents, but are not regulated by the U.S. Food & Drug Administration.

21 Aug 2018

New biosensor tracks oxygen levels in real time in 'organ-on-a-chip' systems

A new biosensor allows researchers to track oxygen levels in real time in "organ-on-a-chip" systems, making it possible to ensure that such systems more closely mimic the function of real organs.

21 Aug 2018

New drug shows potential to prevent painful side effect of therapy

About 50,000 people in the U.S. are diagnosed annually with head, neck, nasal and oral cancers. Most are treated with radiation, and of those, 70-80 percent develop a painful and debilitating side effect called severe oral mucositis.

20 Aug 2018

BOOST-3 clinical trial aims to improve outcomes for severe TBI patients

An estimated 2.5 million Americans sustain a traumatic brain injury, or TBI, each year, according to the Centers for Disease Control and Prevention. Severe TBI contributes to 30 percent of all injury-related deaths, and many who survive are left permanently disabled.

20 Aug 2018

Chronic perinatal hypoxia linked to locomotor miscoordination, long-term cerebellar learning deficits

Oxygen deprivation associated with preterm birth leaves telltale signs on the brains of newborns in the form of alterations to cerebellar white matter at the cellular and the physiological levels. Now, an experimental model of this chronic hypoxia reveals that those cellular alterations have behavioral consequences.

18 Aug 2018

Hologic’s Cynosure division partners with Porter Instrument to distribute nitrous oxide and oxygen system

Hologic, Inc. today announced completion of an agreement between its Cynosure division and Porter Instrument, a business unit of Parker Hannifin Corporation, for distribution rights in the United States and Canada to Porter Instrument’s nitrous oxide and oxygen system, Nitronox.

From Hologic, Inc. 17 Aug 2018

Statins may improve conditions of people with rare lung disease

In the first study of its kind, researchers have found that cholesterol-lowering statins may improve the conditions of people with a rare lung disease called autoimmune pulmonary alveolar proteinosis. The research also suggested that two new tests could help diagnose the condition.

17 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Digital psychiatric therapy can 'rewire' the brain in children with ADHD, study shows

ATENTIV, LLC, pioneers in digital therapies for Attention Deficit/Hyperactivity Disorder and other cognitive disorders, today announced the publication of a recently completed brain imaging study using the ATENTIVmynd Technology platform.

15 Aug 2018

Researchers propose new theory for how rare gene mutations cause Alzheimer's disease

A University of Adelaide-led team of scientists has suggested a potential link between iron in our cells and the rare gene mutations that cause Alzheimer's disease, which could provide new avenues for future research.

14 Aug 2018

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease in individuals who do not have asthma.

14 Aug 2018

Rethinking fundamental rule of stroke care: 'Time is brain!'

In 1993, neurologist Camilo R. Gomez, MD, coined a phrase that for a quarter century has been a fundamental rule of stroke care: "Time is brain!"

14 Aug 2018

Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy

Researchers at the University of Alabama at Birmingham have shed light on an epigenetic reprogramming mechanism that underlies the development of ischemic cardiomyopathy.

13 Aug 2018

Oxidative Stress Hampers Blood Vessel Dilation in Men

Higher levels of oxidative stress in males results in lower levels of cofactor BH needed to make the powerful blood vessel dilator nitric oxide.

13 Aug 2018

Scientists uncover mechanisms responsible for development of fibrosis

Idiopathic pulmonary fibrosis is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process.

10 Aug 2018

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Galectins attach to other proteins via the carbohydrates on their surfaces (sugar-binding proteins). As such they impact on a range of processes in the cell associated with a number of diseases, including heart disease and breast cancer – the most common cancer in women worldwide, with 1.7 million new cases diagnosed in 2012 alone.

10 Aug 2018

Researchers describe underlying mechanisms of congestive heart failure

Congestive heart failure is a terminal disease that affects nearly 6 million Americans. Yet its management is limited to symptomatic treatments because the causal mechanisms of congestive heart failure -- including its most common form, ischemic cardiomyopathy -- are not known.

10 Aug 2018

Oxygen News and Research

Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Wyss researchers create model of the BBB-brain interface using microfluidically linked Organ Chips

New minimally invasive therapy shows promise for long-term reversal of Type 1 diabetes

Researchers raise serious concerns about the accuracy of two baby monitors

New biosensor tracks oxygen levels in real time in 'organ-on-a-chip' systems

New drug shows potential to prevent painful side effect of therapy

BOOST-3 clinical trial aims to improve outcomes for severe TBI patients

Chronic perinatal hypoxia linked to locomotor miscoordination, long-term cerebellar learning deficits

Hologic’s Cynosure division partners with Porter Instrument to distribute nitrous oxide and oxygen system

Statins may improve conditions of people with rare lung disease

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Digital psychiatric therapy can 'rewire' the brain in children with ADHD, study shows

Researchers propose new theory for how rare gene mutations cause Alzheimer's disease

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

Rethinking fundamental rule of stroke care: 'Time is brain!'

Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy

Oxidative Stress Hampers Blood Vessel Dilation in Men

Scientists uncover mechanisms responsible for development of fibrosis

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Researchers describe underlying mechanisms of congestive heart failure

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