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Using estrogen to target drug-resistant breast cancer in mice

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

New imaging technique captures movies of receptors on the surface of living cells

A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children's Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.

23 Apr 2021

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

The National Institutes of Health (NIH) in the USA are to conduct a large-scale clinical trial to evaluate a new fully-human polyclonal antibody therapy targeted at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

New miniaturized model of neuromuscular junction formation provides insight into ALS

Skeletal muscles enable voluntary movements and are controlled by a special type of neurons called motor neurons, which make direct contact with skeletal muscles through so-called neuromuscular junctions (NMJs).

22 Apr 2021

New Phase 3 trial of therapeutics begins enrolling severely ill hospitalized COVID-19 patients

A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure.

22 Apr 2021

Pre-Clinical Vaccine Adjuvant and Therapeutics Manufacturing

Analytik reports how its Microfluidizer® processors are enabling researchers develop a range of therapeutic formulations including vaccine adjuvants, liposomes and lipid nanoparticles.

From Analytik Ltd 22 Apr 2021

National registry needs to be set up for capturing pharma industry payments to clinicians and patient support groups

A national registry to capture all pharma/medical device industry payments and other benefits made to all clinicians, healthcare organizations and patient support groups should be set up as a matter of urgency in the UK, insists an editorial in the Drug and Therapeutics Bulletin (dtb).

22 Apr 2021

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization.

21 Apr 2021

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Human clinical trials have begun on a new vaccine candidate that may protect against not only SARS-CoV-2, the virus that causes COVID-19, but against at least two of the variants emerging around the world.

21 Apr 2021

Algorithm accurately identifies pulmonary arterial hypertension in patients with scleroderma

Screening for a sometimes fatal condition among patients with a rare autoimmune disease could soon - thanks to a computer algorithm - become even more accurate.

21 Apr 2021

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Scientists at City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, have developed a novel, noninvasive liquid biopsy test for detecting lymph node metastasis in individuals with high-risk T1 colorectal carcinoma.

21 Apr 2021

Georgia State professor receives $2.3 million federal grant to study inflammation in infectious diseases

Dr. Jian-Dong Li, professor and director of the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.3 million federal grant to study how overactive inflammatory response is caused in infectious diseases and to further develop novel anti-inflammatory therapeutics.

21 Apr 2021

HSS’ doctor performs first total wrist replacement surgery with KinematX implant

Sixty-nine-year-old Mark Eisen says he waited seven years for a surgery he hopes will change his life. Last week, he had the first total wrist replacement with KinematX™, a new implant co-designed by Scott Wolfe, MD, chief emeritus of the Hand and Upper Extremity Service at Hospital for Special Surgery (HSS). Dr. Wolfe performed the surgery on April 15.

21 Apr 2021

Therapeutics News and Research

Using estrogen to target drug-resistant breast cancer in mice

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

New imaging technique captures movies of receptors on the surface of living cells

NIH to conduct large trial for COVID-19 polyclonal antibody therapies

Experimental drug reverses key symptoms of Alzheimer's disease in mice

New miniaturized model of neuromuscular junction formation provides insight into ALS

New Phase 3 trial of therapeutics begins enrolling severely ill hospitalized COVID-19 patients

Pre-Clinical Vaccine Adjuvant and Therapeutics Manufacturing

National registry needs to be set up for capturing pharma industry payments to clinicians and patient support groups

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Algorithm accurately identifies pulmonary arterial hypertension in patients with scleroderma

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Georgia State professor receives $2.3 million federal grant to study inflammation in infectious diseases

HSS’ doctor performs first total wrist replacement surgery with KinematX implant

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Researchers develop new biomaterial that regrows blood vessels and bone

Limited SARS-CoV-2 spread in childcare centers, finds study

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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