Membrane News and Research

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Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria¬—a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Jan 2017

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters.

19 Jan 2017

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

19 Jan 2017

UIC chemists pinpoint role of cholesterol in cells

Scientists have long puzzled over cholesterol. It's biologically necessary; it's observably harmful - and nobody knows what it's doing where it's most abundant in cells: in the cell membrane.

18 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania.

17 Jan 2017

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease.

17 Jan 2017

OHSU research suggests avenue for developing non-addictive treatments for chronic pain

OHSU research suggests an avenue for developing treatments for chronic pain that harness the medicinal properties of cannabis while minimizing the threat of addiction.

12 Jan 2017

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

12 Jan 2017

Penn Vet researchers identify potential target to fight against Ebola

Viruses and their hosts are in a eternal game of one-upmanship. If a host cell evolves a way to stop a virus from spreading, the virus will look for a new path. And so on and so forth.

12 Jan 2017

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Bacteriophages (phages) are probably the most abundant entities in nature, often exceeding bacterial densities by an order of magnitude.

11 Jan 2017

Researchers provide insights into how phages exhibit high level of precision in cell destruction

Phage therapy, which exploits the ability of certain viruses to infect and replicate within bacteria, shows promise for treating antibiotic-resistant bacterial infections.

11 Jan 2017

Developing high field solid-state NMR for the characterization of complex targets

Solid-state NMR spectroscopy is a technique used by scientists to provide valuable information in the analysis of solid materials. It provides unique and specific insights into the structure, dynamics, and reactivity of all kinds of materials.

From Bruker BioSpin Group 10 Jan 2017

Okayama University researchers uncover potential new therapeutic target for invasive bladder cancer

Researchers at Okayama University have uncovered a potential new therapeutic target for invasive bladder cancer. The GTP hydrolysing enzyme (GTPase), called Dynamin2, facilitates the rapid invasion of cancer into surrounding tissues; inhibiting its activity could limit the progression of bladder cancer.

10 Jan 2017

Researchers find high-resolution structure of immature Zika virus

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads.

10 Jan 2017

TSRI biologists uncover new mechanism behind sense of touch

Biologists on the Florida campus of The Scripps Research Institute have discovered a new mechanism that likely underlies how we feel force or touch. Their study suggests that "rafts" of fatty lipids on the cell surface act as compartments to keep certain enzymes from mixing with their binding partners.

6 Jan 2017

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next.

6 Jan 2017

Membrane News and Research

Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

UIC chemists pinpoint role of cholesterol in cells

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

OHSU research suggests avenue for developing non-addictive treatments for chronic pain

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Penn Vet researchers identify potential target to fight against Ebola

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Researchers provide insights into how phages exhibit high level of precision in cell destruction

Developing high field solid-state NMR for the characterization of complex targets

Okayama University researchers uncover potential new therapeutic target for invasive bladder cancer

Researchers find high-resolution structure of immature Zika virus

TSRI biologists uncover new mechanism behind sense of touch

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Researchers uncover cell membrane protein that regulates gene linked to schizophrenia

Study finds evidence for unique electrical properties of human pyramidal neurons

Research reveals causes of motor abnormalities in low birth weight babies

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo