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Newspapers examine debate over affordable drugs in developing countries

The Los Angeles Times examines how "activists in Washington, and Thailand and other developing countries are accusing the Obama administration of endangering access to affordable drugs to fight AIDS and other epidemic diseases."

21 Aug 2009

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population-based cohort study

Rosiglitazone, a drug used to treat type 2 diabetes, is associated with an increased risk of heart failure and death among older patients compared to a similar drug (pioglitazone), concludes a study published on bmj.com today.

20 Aug 2009

Cambodia's maternal mortality; drugs in Uganda; cholera risk in Zimbabwe; HIV laws in Niger

A lack of outreach by public health officials and rural villagers' preference for traditional midwives have hindered efforts to reduce maternal morality in Cambodia, government officials said recently at regional conference, the Phnom Penh Post reports.

20 Aug 2009

Chemical components of elderberry, cinnamon and green tea extracts block HIV viruses from infecting cells

The development of new antiviral drugs has had a tremendous impact on the quality of life and life expectancy of HIV-positive and AIDS patients, as the drugs effectively disrupt the replication cycle of the HIV virus. Yet the regular use of those drugs - such as zidovudine (also known as azidothymidine or AZT), protease inhibitors, and highly active antiretroviral therapy (HAART) involving multidrug therapies - has led to resistant HIV strains.

20 Aug 2009

Software suite for comprehensive analysis of cardiac safety released by NewCardio

NewCardio, Inc., (OTC Bulletin Board: NWCI) a cardiac diagnostic technology provider, today announced that the Company has formally launched its lead product, QTinno(TM), a software suite that provides an automated, comprehensive analysis of cardiac safety for the pharmaceutical industry.

20 Aug 2009

Shape-changing in proteins opens new avenue for drug discovery

Computational biologists at the University of Pittsburgh School of Medicine have shown that proteins have an intrinsic ability to change shape, and this is required for their biological activity. This shape-changing also allows the small molecules that are attracted to a given protein to select the structure that permits the best binding. That premise could help in drug discovery and in designing compounds that will have the most impact on protein function to better treat a host of diseases.

20 Aug 2009

Fluxion Biosciences receives a $1.8 million NIH grant for developing microfluidic platform

Fluxion Biosciences, a leading developer of microfluidic systems for functional cell analysis, today announced that it has received a $1.8 million NIH grant for the development of a high-throughput screening platform for anti-microbial drug discovery.

From Fluxion Biosciences 20 Aug 2009

Some HIV-positive Ugandans' not receiving antiretrovirals

Some HIV-positive people in Uganda "cannot be put on the national antiretroviral [ARV] programme because it is already saturated and funds for new patients are not available," the Independent reports. According to the newspaper, roughly 360,000 HIV-positive Ugandans are eligible for antiretroviral treatment because their CD4 counts are below the WHO's threshold of 350; however, about half of them currently do not have access to ARVs.

20 Aug 2009

Scientists find another mechanism that destroys tumor cells

Cells don't like to be alone. In the early stages of tumor formation, a cell might be pushed out of its normal home environment due to excessive growth. But a cell normally responds to this homeless state by dismantling its nucleus, packing up its DNA, and offering itself to be eaten by immune system cells. Simply put, the homeless cell kills itself. This process, known as apoptosis, typically stops potential cancer cells before they have a chance to proliferate.

20 Aug 2009

New strategy found to increase the efficacy of protein-based drugs

A new method for attaching a large protective polymer molecule to a protein appears to improve protein drugs significantly.

20 Aug 2009

Diet pills, alcohol, caffeine, nicotine, amphetamines and cocaine abused by patients with eating disorders

Between 11 and 13 million people in the U.S. have eating disorders and at least one million will die from their disorder. It is not unusual for women and girls struggling with eating disorders to either abuse or become dependent on over-the-counter substances.

20 Aug 2009

National Institute on Drug Abuse funds study on development of prenatally cocaine-exposed children

Teen years are filled with experimenting. Sometimes that means trying some risky behaviors.

20 Aug 2009

Medication safety program on safe prescribing procedures for narcotic drugs launched

Warnings by the Food and Drug Administration (FDA) and increasing misuse and overdoses are telling reminders of the dangers pain medications can present. A recent study reveals that one in 10 high school students have tried opioid drugs and the prevalence of young adults using narcotics for non-medical use is the highest in 15 years.

20 Aug 2009

Vanderbilt enters Chemical Biology Consortium as a Chemical Diversity Center to develop cancer treatment drugs

Vanderbilt University has been selected as one of 10 centers in the nation to participate in the Chemical Biology Consortium (CBC), a major new initiative to facilitate the discovery and development of new agents to treat cancer.

20 Aug 2009

Aton Pharma markets preservative-free drugs for glaucoma

Aton Pharma, Inc., a diversified specialty pharmaceutical company, today announced it has launched new education, distribution, sampling and reimbursement programs for TIMOPTIC(R) in OCUDOSE(R), the only preservative-free medication for glaucoma available in the United States. Aton acquired the U.S. marketing rights in February to the TIMOPTIC product line from Merck & Co., Inc. TIMOPTIC (timolol maleate) is a non-selective beta-adrenergic receptor blocking agent indicated for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. As many as 2.25 million Americans suffer from open-angle glaucoma.

20 Aug 2009

Supplemental Manufacturing and Ingredients forges manufacturing agreement with HealthSport's subsidiary, InnoZen

InnoZen, Inc., a wholly owned subsidiary of HealthSport, Inc. (OTC Bulletin Board: HSPO) announced today that it has entered into a manufacturing agreement with Supplemental Manufacturing and Ingredients, LLC ("SMI"), a cGMP certified manufacturer based in Tempe, Arizona. As part of the Agreement, SMI has committed to purchasing $1,000,000 worth of HealthSport common stock.

20 Aug 2009

DNA-encased carbon nanotubes used for treating human prostate cancer tumors in mice

Researchers at Wake Forest University School of Medicine have destroyed prostate cancer tumors in mice by injecting them with specially-coated, miniscule carbon tubes and then superheating the tubes with a brief zap of a laser.

20 Aug 2009

Battle over proposal to disclose drug price deals

"Some Democratic lawmakers looking for ways to overhaul the nation's health-care system are targeting the companies that handle drug benefits for more than 210 million Americans, setting off a lobbying battle over how much pricing information the companies should disclose," The Wall Street Journal reports.

19 Aug 2009

Researchers find connection between eye disease and arginase

Elevated levels of the enzyme arginase contribute to vascular eye damage and Medical College of Georgia researchers say therapies to normalize its levels could halt progression of potentially blinding diseases such as diabetic retinopathy.

19 Aug 2009

Light-activated delivery system enhances anti-tumour drug potency

The effects of tumour-targeting drugs in mice are significantly enhanced by PCI Biotech's light-activated delivery system, a new study shows. Researchers say this dual therapy approach could be employed to increase the effect and lower the side effects of anti-cancer drugs in humans.

19 Aug 2009

Drugs News and Research

Newspapers examine debate over affordable drugs in developing countries

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population-based cohort study

Cambodia's maternal mortality; drugs in Uganda; cholera risk in Zimbabwe; HIV laws in Niger

Chemical components of elderberry, cinnamon and green tea extracts block HIV viruses from infecting cells

Software suite for comprehensive analysis of cardiac safety released by NewCardio

Shape-changing in proteins opens new avenue for drug discovery

Fluxion Biosciences receives a $1.8 million NIH grant for developing microfluidic platform

Some HIV-positive Ugandans' not receiving antiretrovirals

Scientists find another mechanism that destroys tumor cells

New strategy found to increase the efficacy of protein-based drugs

Diet pills, alcohol, caffeine, nicotine, amphetamines and cocaine abused by patients with eating disorders

National Institute on Drug Abuse funds study on development of prenatally cocaine-exposed children

Medication safety program on safe prescribing procedures for narcotic drugs launched

Vanderbilt enters Chemical Biology Consortium as a Chemical Diversity Center to develop cancer treatment drugs

Aton Pharma markets preservative-free drugs for glaucoma

Supplemental Manufacturing and Ingredients forges manufacturing agreement with HealthSport's subsidiary, InnoZen

DNA-encased carbon nanotubes used for treating human prostate cancer tumors in mice

Battle over proposal to disclose drug price deals

Researchers find connection between eye disease and arginase

Light-activated delivery system enhances anti-tumour drug potency

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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