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New study maps links between 625 genes and different chemotherapy treatments

Despite the great successes of targeted cancer drugs and the promise of novel immunotherapies, the vast majority of people diagnosed with cancer are still first treated with chemotherapy. Now a new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use the genetic profile of a patient's tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.

18 Apr 2018

Study: Hot spots of type 1 diabetes found in food swamps

Hot spots of type 1 diabetes in New York City are found in food swamps, areas with a higher proportion of fast food restaurants, for children and adults with type 1 diabetes according to a new study published in the Endocrine Society's Journal of the Endocrine Society.

17 Apr 2018

Scientists analyze nanostructure of chicken eggshells

The results of a study recently published in the prestigious international journal Science Advances have enabled researchers to better understand the role of eggshells in embryo development and hatching.

17 Apr 2018

Mouse study shows how tungsten accumulates in the bones

New research shows how and where tungsten accumulates in bones of mice exposed to the element through drinking water. The findings, by a team of chemists and biologists at McGill University, could add to doubts over the once-universal assumption that tungsten poses little or no health risk to the general human population.

17 Apr 2018

Two immune checkpoint inhibitors efficiently block leukemia development in preclinical tests

Chronic lymphocytic leukemia is a hematological malignancy that originates in the blood-forming cells of the bone marrow and spreads to other organs through the bloodstream.

17 Apr 2018

Middle ear infection can lead to deadly neurological complications

While antibiotics have greatly reduced the dangers of ear infections, serious neurological complications, including hearing loss, facial paralysis, meningitis and brain abscess still occur, according to an article in the journal Current Neurology and Neuroscience Reports.

16 Apr 2018

Researchers generate stable cartilage tissue from adult mesenchymal stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

16 Apr 2018

Researchers use graphene to disrupt biofilms on dental implants

Researchers from Chalmers University of Technology, Sweden have demonstrated that a layer of graphene can form a protective film on the surface of implants that could prevent bacterial infection.

16 Apr 2018

Researchers use graphene to disrupt biofilms on dental implants

Researchers from Chalmers University of Technology, Sweden have demonstrated that a layer of graphene can form a protective film on the surface of implants that could prevent bacterial infection.

16 Apr 2018

Tiny layer of graphene flakes becomes deadly weapon against bacteria on implants

A tiny layer of graphene flakes becomes a deadly weapon and kills bacteria, stopping infections during procedures such as implant surgery. This is the findings of new research from Chalmers University of Technology, Sweden, recently published in the scientific journal Advanced Materials Interfaces.

16 Apr 2018

Receptor that detects heat of red chili pepper may help protect the brain after TBI

A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.

13 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

Lithuanian researchers use freeze-drying technique to create sponge-like wound dressings

Group of researchers at Kaunas University of Technology, Lithuania are developing new generation sponge-like wound dressings with hyaluronic acid. Antimicrobial, antioxidant, anti-inflammatory wound dressings stimulate tissue regeneration and can be especially efficient in treating deep wounds that are difficult to heal.

12 Apr 2018

Experimental peptide drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide drug shows promise against the often-lethal cancer acute myeloid leukemia and describe how the drug works at the molecular level.

11 Apr 2018

Researcher explores how children develop immunity to malaria as they grow older

Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually--more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery.

11 Apr 2018

NIH study uncovers genetic basis of 'dripping candle wax' bone disease

Researchers at the National Institutes of Health worked with 15 patients from around the world to uncover a genetic basis of "dripping candle wax" bone disease.

11 Apr 2018

Transcription factor Sp7 found to play key role in tooth development

Amjad Javed, Ph.D., and University of Alabama at Birmingham colleagues have found a key role in tooth development for the transcription factor Specificity protein 7, or Sp7.

11 Apr 2018

Is there such a thing as normal aging?

For 93-year-old Joseph Brown, the clearest sign of aging was his inability the other day to remember he had to have his pants unzipped to pull them on.

11 Apr 2018

PCOS linked to increased risk of mental health disorders

Women with polycystic ovary syndrome, the most common hormone condition among young women, are prone to mental health disorders, and their children face an increased risk of developing attention deficit hyperactivity disorder and autism spectrum disorder, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

11 Apr 2018

Scripps Florida researchers awarded $2.875 million to destroy common form of leukemia

Christoph Rader, PhD, associate professor at the Florida campus of The Scripps Research Institute, has been awarded a $2.875 million, five-year grant from the National Cancer Institute to develop unique antibody-drug conjugates engineered to eradicate one of the most common forms of leukemia, chronic lymphocytic leukemia

10 Apr 2018