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Yale scientists build powerful genomic research platform to study cervical cancer

Yale Cancer Center scientists have built a powerful genomic research platform to study cervical cancer, a disease that often is untreatable if it progresses after surgery or primary chemo-radiation treatment.

17 Oct 2019

Study shows link between high-fat diet and earlier appearance of Alzheimer's markers in the brain

Once it begins, Alzheimer's disease progresses systematically and aggressively, attacking victims on multiple fronts. But scientists studying the disease operate the same way - like Kent State University's own Gemma Casadesus Smith, Ph.D.

17 Oct 2019

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

With a shared vision of accelerating genomic discovery and improving patient outcomes, leaders from Boston Children's Hospital, Children's Hospital of Philadelphia, and Cincinnati Children's Hospital came together in 2015 to form the Genomics Research and Innovation Network.

17 Oct 2019

UChicago helps lead $8.8 million effort to make cancer research data more accessible and useful

The University of Chicago will help lead an $8.8 million effort to make the vast quantity of cancer research data being produced more accessible and useful to clinicians and researchers around the world.

16 Oct 2019

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

The National Institutes of Health has awarded a Michigan State University researcher a $2.1 million, five-year grant to search vast databases of existing drugs.

16 Oct 2019

Scientists discover how malaria switched host from African gorillas to humans

Researchers have revealed the series of events that probably led to the world’s deadliest form of malaria being able to jump from ancient great apes to humans.

16 Oct 2019

NIH awards new contract to integrate pathogen and vector genomics database

A team led by scientists at the University of Pennsylvania and University of Georgia provides thousands of researchers around the world with access to the Eukaryotic Pathogen Genomics Database (EuPathDB.org), a collection of resources for analyzing large-scale datasets associated with microbial pathogens.

16 Oct 2019

Researcher explores biological processes that cause fertility problems in humans

With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility problems in humans.

16 Oct 2019

Machine learning system may offer warnings about negative side effects of drug-drug interactions

The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage and even death.

15 Oct 2019

Researchers reveal mechanism involved in altering DNA methylation in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.

15 Oct 2019

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

Researchers have discovered new changes in blood samples associated with Alzheimer's disease. A new international study was conducted on disease-discordant Finnish twin pairs: one sibling suffering from Alzheimer's disease and the other being cognitively healthy.

15 Oct 2019

How Is Ophthalmology Changing To Meet New Challenges?

Ophthalmology, a highly dynamic space in vision loss and age-related eye diseases with approximately 1.3 billion people living with vision impairment.

From Santen Pharmaceutical Co., Ltd. 15 Oct 2019

Cleveland Clinic-led researchers develop novel genetic-based epilepsy risk scores

An international team of researchers led by Cleveland Clinic has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment.

14 Oct 2019

Medical and surgical eye care experts gather in San Francisco for AAO 2019

More than 25,000 are expected to attend the American Academy of Ophthalmology's 123rd annual meeting, AAO 2019, from Oct. 12-15 at the Moscone Center in San Francisco.

11 Oct 2019

Jumping genes can contribute to rare childhood developmental disorders

The largest study of its kind into childhood developmental disorders has discovered that jumping genes cause genetic changes in some patients with undiagnosed neurodevelopmental diseases.

11 Oct 2019

Researchers develop customized drug treatment to bypass patient’s unique mutation

An unprecedented case at Boston Children's Hospital shows that it's possible to do something that's never been done before: identify a patient's unique mutation, design a customized drug to bypass it, manufacture and test the drug, and obtain permission from the Food and Drug Administration (FDA) to begin treating the patient -- all in less than one year.

11 Oct 2019

Fetal gut has more well-developed immune capabilities than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh challenges that paradigm, and provides the first comprehensive look at the immune system of the developing gut.

10 Oct 2019

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

In 2015, EPFL researchers led by Melanie Blokesch published a seminal paper in Science showing that the bacterium responsible for cholera, Vibrio cholerae, uses a spring-loaded spear to literally stab neighboring bacteria and steal their DNA.

8 Oct 2019

Histone modifications play important role in 'zygotic genome activation'

Scientists at Tokyo Institute of Technology observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to "histone H3", one of the proteins around which DNA is bound, play an important role in "zygotic genome activation" or transition of control of zebrafish embryonic development from maternal material to the zygote .

8 Oct 2019

DNA metabarcoding could improve analysis of human diet

A study has shown that DNA metabarcoding serves as a powerful new tool for monitoring humans’ intake of plants.

8 Oct 2019

Genomic News and Research

Yale scientists build powerful genomic research platform to study cervical cancer

Study shows link between high-fat diet and earlier appearance of Alzheimer's markers in the brain

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

UChicago helps lead $8.8 million effort to make cancer research data more accessible and useful

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

Scientists discover how malaria switched host from African gorillas to humans

NIH awards new contract to integrate pathogen and vector genomics database

Researcher explores biological processes that cause fertility problems in humans

Machine learning system may offer warnings about negative side effects of drug-drug interactions

Researchers reveal mechanism involved in altering DNA methylation in cancer

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

How Is Ophthalmology Changing To Meet New Challenges?

Cleveland Clinic-led researchers develop novel genetic-based epilepsy risk scores

Medical and surgical eye care experts gather in San Francisco for AAO 2019

Jumping genes can contribute to rare childhood developmental disorders

Researchers develop customized drug treatment to bypass patient’s unique mutation

Fetal gut has more well-developed immune capabilities than previously thought

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

Histone modifications play important role in 'zygotic genome activation'

DNA metabarcoding could improve analysis of human diet

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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