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Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

The importance of early cancer screening

In this interview, Thomas Qiu, Senior Product Manager from BGI Genomics, talks to NewsMedical about current global cancer rates, and the importance of early cancer screening.

From BGI Genomics 1 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that high glucose impairs the antitumor activity of immune effector γδ-T cells, which contributes to the increased cancer risk in diabetes and that metabolic reprogramming by glucose control may improve the antitumor activity of γδ-T cells.

30 Nov 2022

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Studying mice has filled encyclopedias with breakthrough medical discoveries. But when it comes to brain cancers, the little rodents have long exhibited fundamental limitations.

30 Nov 2022

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two?

30 Nov 2022

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Inactivation of previously unknown gene found to be a likely culprit in the onset of pancreatic cancer

New research out of VCU Massey Cancer Center points to the inactivation of a previously unidentified gene as a likely culprit in the development of pancreatic cancer.

30 Nov 2022

Study on mpox epidemiology in New York during summer 2022

Researchers presented a summary of their experience of identifying, managing, and vaccinating monkeypox (MPX) virus (MPXV)-infected individuals in New York during the summer season of 2022.

30 Nov 2022

Existing drug may help decrease side effects of widely used cancer treatment

A Michigan State University researcher is part of an international team that found an existing drug may help decrease side effects of cisplatin, a widely used cancer treatment that was discovered at MSU in 1965.

30 Nov 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Researchers investigated whether severe COVID-19 patients exhibited inflammation and immune activation three months after hospitalization and explored the associations among COVID-19 severity, long COVID, and immune activation.

30 Nov 2022

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

To commemorate World AIDS Day, News Medical spoke to Dr. Larry Corey, an internationally renowned expert in virology, immunology, and vaccine development, and the former president and director of Fred Hutch, about his work within the field of HIV/AIDS research and vaccine development.

30 Nov 2022

Review: Phenotypes and origins of myeloid-derived suppressor cells

A new review was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more."

30 Nov 2022

Cryoablation is more effective than heat-based treatment for some small kidney cancers

For patients with early-stage renal cell carcinomas (RCCs) that measure between 3 and 4 centimeters, a procedure that destroys the cancer by freezing – called cryoablation – yields a lower-risk of cancer-related death compared to heat-based thermal ablation, reports a preliminary study in The Journal of Urology®, an Official Journal of the American Urological Association.

29 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Understanding how cancer cells evolve from healthy brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed.

29 Nov 2022

Study shines light on how ultrafine particles promote lung cancer progression

While it may seem common knowledge that smoking is bad for your lungs, if and how ultrafine particles present in cigarette smoke impact the development and progression of lung cancer remains unclear.

29 Nov 2022

Blood tests may be able to guide treatment discussions for patients with metastatic cancer

As cancers grow and potentially spread to new parts of the body, they often shed cells and DNA into the blood stream. DNA can be analyzed for both the amount of DNA present and whether any potential mutations exist that may aid providers in deciding on treatments.

29 Nov 2022

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types.

29 Nov 2022

Tumor News and Research

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

The importance of early cancer screening

Detection of filoviruses by the innate immune system

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Stem cell crosstalk with the microenvironment creates a loop of tumor-promoting factors

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Inactivation of previously unknown gene found to be a likely culprit in the onset of pancreatic cancer

Study on mpox epidemiology in New York during summer 2022

Existing drug may help decrease side effects of widely used cancer treatment

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

Review: Phenotypes and origins of myeloid-derived suppressor cells

Cryoablation is more effective than heat-based treatment for some small kidney cancers

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Study shines light on how ultrafine particles promote lung cancer progression

Blood tests may be able to guide treatment discussions for patients with metastatic cancer

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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