Clinical Trial News and Research

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Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Widely used food additive alters the intestinal environment of healthy persons, research shows

New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

30 Nov 2021

Daily prune consumption has a protective effect on men’s bone health, research reports

New research from San Diego State University's School of Exercise and Nutritional Sciences reports that eating prunes daily has a protective effect on bone health in men over 50.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

Imaging drug that illuminates ovarian cancer tissue when exposed to fluorescent light gets FDA approval

The U.S. Food and Drug Administration (FDA) today approved an imaging drug known as Cytalux (pafolacianine), which is attracted to ovarian cancer tissue and illuminates it when exposed to fluorescent light, allowing surgeons to more easily find and more precisely remove the cancer.

30 Nov 2021

Telehealth-delivered exercise and weight loss program for people with knee osteoarthritis or obesity

A randomized trial found that video-based, telehealth-delivered exercise and weight loss programs with online educational support improved pain and function in people with knee osteoarthritis and overweight or obesity.

30 Nov 2021

Many long-haul COVID-19 patients may experience breathing issues, chronic fatigue syndrome

Many long-haul COVID-19 patients have chronic fatigue syndrome and other breathing issues months after their initial COVID-19 diagnosis, according to study in JACC: Heart Failure, which is the first of its kind to identify a correlation between long-haul COVID-19 and chronic fatigue syndrome.

29 Nov 2021

$Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients$

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

A research team from the Graduate School of Medicine at Osaka University has started an investigator-initiated clinical trial of sodium astatine ([211At]NaAt) injection for refractory differentiated thyroid cancer patients.

29 Nov 2021

Childhood cancer diagnosis not delayed in Canada during the pandemic, study says

During the first 9 months of the COVID-19 pandemic, researchers did not find a significant difference in the number of new cancer diagnoses in Canadian children compared with before the pandemic, according to a study published in CMAJ.

29 Nov 2021

Heart failure patients may benefit from common type 2 diabetes drug

Dapagliflozin, a drug commonly used to treat type 2 diabetes, improved symptoms and physical limitations in patients with heart failure with preserved ejection fraction, according to clinical trial results published in Nature Medicine.

29 Nov 2021

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

A study developed a protein-based subunit vaccine, PHH-1V, that consisted of a recombinant RBD fusion heterodimer of the alpha) and beta variants of SARS-CoV-2.

26 Nov 2021

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Scientists have tested the efficacy of BriLife®-vaccinated human sera in neutralizing more infectious and probably more virulent SARS-CoV-2 variants.

26 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

Researchers investigate Moderna COVID-19 vaccine efficacy

Researchers have been investigating the vaccine efficacy of the mRNA-1273 vaccine.

25 Nov 2021

Study finds under-representation of certain populations in cancer clinical trials

In a study examining disparities and trends in the inclusion of minorities, women, and older patients in cancer clinical trials, investigators found that certain populations remain under-represented.

25 Nov 2021

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

On November 23, 2021, the California Institute for Regenerative Medicine (CIRM) governing board approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

New robotic device provides innovative motor and cognitive rehabilitation service

A Universidad Carlos III de Madrid spin-off, Inrobics Social Robotics, S.L.L., has developed a robotic device that provides an innovative motor and cognitive rehabilitation service that can be used at health centers as well as at home.

24 Nov 2021

CDC study finds Pfizer-BioNTech COVID vaccine provides high protection against hospitalization in adolescents

New research from the Centers for Disease Control & Prevention (CDC) suggest vaccines are highly protective against severe acute respiratory coronavirus 2 (SARS-CoV-2). Two doses of the Pfizer-BioNTech vaccine showed a 93% effectiveness against hospitalization. The findings add to a previous clinical trial that found vaccinated adolescents with 100% protection against SARS-CoV-2 infections.

23 Nov 2021

Clinical Trial News and Research

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Widely used food additive alters the intestinal environment of healthy persons, research shows

Daily prune consumption has a protective effect on men’s bone health, research reports

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

Imaging drug that illuminates ovarian cancer tissue when exposed to fluorescent light gets FDA approval

Telehealth-delivered exercise and weight loss program for people with knee osteoarthritis or obesity

Many long-haul COVID-19 patients may experience breathing issues, chronic fatigue syndrome

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

Childhood cancer diagnosis not delayed in Canada during the pandemic, study says

Heart failure patients may benefit from common type 2 diabetes drug

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

Researchers investigate Moderna COVID-19 vaccine efficacy

Study finds under-representation of certain populations in cancer clinical trials

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

New robotic device provides innovative motor and cognitive rehabilitation service

CDC study finds Pfizer-BioNTech COVID vaccine provides high protection against hospitalization in adolescents

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