Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

TSRI study unveils new twist in immune biology

A new study, led by scientists at The Scripps Research Institute, reveals a surprising twist in immune biology.

2 Aug 2016

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.

30 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

UAB researchers uncover vital mechanism for L-DOPA-induced-dyskinesia

Though the drug levodopa can dramatically improve Parkinson's disease symptoms, within five years one-half of the patients using L-DOPA develop an irreversible condition -- involuntary repetitive, rapid and jerky movements.

29 Jul 2016

Study identifies two proteins crucial for self-renewal of skin stem cells

Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days.

29 Jul 2016

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Study reports sampling method used for new breast cancer tests may need to be refined

Not only is breast cancer more than one disease, but a single breast cancer tumor can vary within itself, a finding that University of Pittsburgh Cancer Institute researchers discovered has the potential to lead to very different patient treatment plans depending on the tumor sample and diagnostic testing used.

28 Jul 2016

Changes in the brain's pleasure center may decrease physical activity in postmenopausal women

As women enter menopause, their levels of physical activity decrease; for years scientists were unable to determine why.

28 Jul 2016

ZMYND8 protein can suppress metastasis-linked genes in prostate cancer

Although it reads like European license plate number, a protein known as ZMYND8 has demonstrated its ability to block metastasis-linked genes in prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center.

28 Jul 2016

Study finds risk markers for Parkinson's disease hiding in unusual spots

Clues that point toward new risk mechanisms for developing Parkinson's disease are hiding in some unusual spots, according to a study published today in Scientific Reports

28 Jul 2016

Scientists discover modified human protein involved in Ebola virus replication

A newly identified requirement of a modified human protein in ebolavirus (EBOV) replication, may unlock the door for new approaches to treating Ebola.

26 Jul 2016

Predictive power of computational toxicology demonstrated with crowd-sources scientific challenge

Results of the Systems Toxicology Computational Challenge have demonstrated how transcriptomics information present in the blood can be used to predict whether people have been exposed or not exposed to specific toxicants.

22 Jul 2016

Researchers unveil engineered protein to suppress cancer-promoting message within cells

Over a century of research has shined light on the once-murky innards of our cells, from the genes that serve as our "blueprints" to the proteins and other molecules that are our cellular taskmasters.

22 Jul 2016

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.

21 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

TSRI study reveals new approach to intervene in deadly disease

In a new study, scientists at The Scripps Research Institute have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis.

From Paxman 21 Jul 2016

New study sheds light on pathogenesis of DNA lesions present in leukemia

Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia.

20 Jul 2016

Enhancers can boost frequency of transcriptional bursting, study shows

A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps.

20 Jul 2016

New virus-based method opens wide range of options to treat various diseases

The ability to switch disease-causing genes on and off remains a dream for many physicians, research scientists and patients.

20 Jul 2016

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes.

19 Jul 2016