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Cholera-causing bacteria steal large stretches of intact DNA to become more efficient

A new paper shows that the cholera germ is an inveterate and rapacious gene stealer, robbing other competing bacteria of up to 150 genes (over 150,000 base pairs) in a single attack. To put this in perspective, the cholera pathogen carries only about 4,000 genes altogether.

8 Oct 2019

New insight into meningioma - possibility of targeted therapy

A new study published in the journal Oncotarget shows that certain mutations in the brain tumor called meningioma may help identify patients who have a better chance of recovery. This could help physicians make better clinical decisions based on more accurate diagnoses. It has also unveiled some of the genes that go wrong in meningiomas, as well as showing how targeted therapy could one day help fight this tumor.

7 Oct 2019

Study highlights practice patterns and factors associated with prognosis of male breast cancer

A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

7 Oct 2019

Understanding treatment and prognosis of male breast cancer

October is Breast Cancer Awareness Month, an annual campaign to raise awareness about the potentially-fatal disease. Breast cancer is known as an illness that affects mostly women, but about 1 percent of all breast cancers affect men, too.

7 Oct 2019

Research provides new insights into tumorigenesis of meningioma

The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy.

5 Oct 2019

Stanford study finds genetic similarities among species that use sound waves to navigate

Insect-eating bats navigate effortlessly in the dark and dolphins and killer whales gobble up prey in murky waters thanks in part to specific changes in a set of 18 genes involved in the development of the cochlear ganglion -- a group of nerves that transmit sound from the ear to the brain, according to a study by researchers at Stanford University.

4 Oct 2019

New sensor technology to revolutionize treatment and cure of tuberculosis

A trial involving an edible sensor connected to a paired mobile, that enables medical staff to remotely see patients` intake of tuberculosis (TB) medicine, has produced superior results to directly observed therapy (DOT), where a healthcare worker watches the patient swallow medication, leading researchers to suggest that the technology could be a game changer in high prevalence countries where treatment adherence remains a stumbling block to eliminating TB.

4 Oct 2019

Researchers identify new targets to treat fibrotic diseases

When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term - but bad when myofibroblast activation gets out of hand.

4 Oct 2019

ATCC launches new database of reference-quality genome sequences to aid biological research

ATCC launched its new ATCC Genome Portal, a publicly available database of reference-quality genome sequences matched to authenticated ATCC biological materials that will help researchers interpret and reproduce their results with confidence.

From American Type Culture Collection (ATCC) 4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

$28 million grant supports Cincinnati Children's role as coordinating center for Rare Diseases Clinical Research Network

The federal agency that oversees a large network of research centers seeking cures for hundreds of rare, disabling and often fatal diseases has named Cincinnati Children's as its new data management and coordinating center.

4 Oct 2019

New mechanism that controls DNA repair identified

Deoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer.

2 Oct 2019

Certain fungi increase pancreatic cancer risk, study finds

Certain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds.

2 Oct 2019

Targeted therapy slows disease progression and improves survival for prostate cancer

A new PARP-inhibitor has been shown to significantly delayed cancer progression among patients with prostate cancer who had cancer cells with faulty DNA repair genes.

2 Oct 2019

Using cloning technology to prevent esophageal cancer

Researchers at the University of Houston have replicated the genetic mechanism underlying the transformation of benign esophageal cells into a malignant tumor.

2 Oct 2019

The Slaight Family Foundation supports UHN to deliver enhanced care for seniors outside the hospital

The Silver Tsunami will see an unprecedented number of seniors in Canada, which is also true throughout North America.

1 Oct 2019

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

A bit more than a million years ago, a population of Southeastern Asian mice developed the remarkable ability to regrow axons after injury to its brain.

1 Oct 2019

Detecting neurocognitive change in children with acute lymphoblastic leukemia

Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. As a result, these changes can lead to challenges with school, obtaining future employment and overall quality of life into adulthood, even though cancer treatment may have been successful.

1 Oct 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal.

30 Sep 2019

Genomic News and Research

Cholera-causing bacteria steal large stretches of intact DNA to become more efficient

New insight into meningioma - possibility of targeted therapy

Study highlights practice patterns and factors associated with prognosis of male breast cancer

Understanding treatment and prognosis of male breast cancer

Research provides new insights into tumorigenesis of meningioma

Stanford study finds genetic similarities among species that use sound waves to navigate

New sensor technology to revolutionize treatment and cure of tuberculosis

Researchers identify new targets to treat fibrotic diseases

ATCC launches new database of reference-quality genome sequences to aid biological research

Study explores how macrophage specialization gets disrupted by liver disease

$28 million grant supports Cincinnati Children's role as coordinating center for Rare Diseases Clinical Research Network

New mechanism that controls DNA repair identified

Certain fungi increase pancreatic cancer risk, study finds

Targeted therapy slows disease progression and improves survival for prostate cancer

Using cloning technology to prevent esophageal cancer

The Slaight Family Foundation supports UHN to deliver enhanced care for seniors outside the hospital

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

Detecting neurocognitive change in children with acute lymphoblastic leukemia

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Breast, ovarian cancer drug more effective than targeted hormone therapy in some men with prostate cancer

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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