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Lancet Infectious Diseases examines spread of XDR-TB

The journal Lancet Infectious Diseases examines the worldwide spread of extensively drug-resistant tuberculosis (XDR-TB). Currently, about 500,000 of the 9 million new cases of TB that are identified each year are strains of XDR-TB. "Drug resistance is largely man-made - it is vitally important to review antibiotic treatment strategies and to ensure the Stop TB Strategy is fully applied to prevent further selection of drug-resistant mutants," Leonard Amaral of Universidade Nova de Lisboa said.

24 Jun 2009

IRIN examines PEPFAR funding of IDU programs

IRIN examines a recent comment piece in the journal Lancet that argues PEPFAR can do more to prevent the spread of HIV among injecting drug users (IDUs) in Africa (IRIN, 6/24).

24 Jun 2009

Scientists investigate health benefits of molecule associated with male sexual arousal

Medical scientists at the University of Leicester are investigating how signalling molecules known to control blood pressure and penile erection act to regulate brain function and which have potential for treatments of migraine, chronic pain, epilepsy and Alzheimer's disease.

24 Jun 2009

Smoking provokes migraine attacks

Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in The Journal of Headache and Pain.

24 Jun 2009

Intervention strategies to curb spread of pandemic flu

Mathematicians, biostaticians and public health officials from Canada, Mexico and the United States will gather at Arizona State University this week to focus on understanding, possibly mitigating the spread of the H1N1 flu virus. They are planning to take up the challenge of proposing science-based strategies that can slow the spread of pandemic flu.

24 Jun 2009

Swine flu tally has U.S. top and Australia 6th

The latest update, # 52, from the World Health Organisation on the influenza A H1N1 pandemic (swine flu), says as of the 22nd of June the grand total of those infected is now 52,160 including 231 deaths.

23 Jun 2009

Good bet in market pullback: health-care shares

"As sentiment and the stock market increasingly look bearish, look for the recent outperformance in health care to continue," The Wall Street Journal reports.

23 Jun 2009

Details remain unclear on Medicare drug deal

The White House formally announced the drug manufacturers' plan to lower Medicare drug prices Monday. While details still remain unclear, it appears drug companies may benefit from the deal.

23 Jun 2009

Firms tweak benefit plans in District of Columbia and Baltimore area

The Washington Post reports that "More Washington- and Baltimore-area employers are shifting health-insurance costs to workers, offering high-deductible health plans and imposing restrictions on prescription-drug coverage to save money in the recession, according to a new survey by area human resources managers to be released today. But to keep good workers from jumping ship, according to the survey, more employers are offsetting the restrictions by beefing up other perks -- giving staff more flexibility in taking time off and working from home, and extending benefits to domestic partners."

23 Jun 2009

Merck partners with non-profit for neglected diseases initiative

The pharmaceutical company, Merck, announced Monday it was partnering with the non-profit Drugs for Neglected Diseases initiative (DNDi) in an effort to improve treatments for neglected tropical diseases (NTD), the AP/CNBC reports.

23 Jun 2009

Scientists block Ebola infection in cell-culture experiments - could lead to first therapy

Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells.

23 Jun 2009

New biomarker predicts brain tumor's response to cediranib therapy

A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respond better to anti-vascular endothelial growth factor therapy, specifically cediranib.

23 Jun 2009

Discovery of potent metastasis inhibitor

Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment.

23 Jun 2009

New tuberculosis drug targets

A fundamental question about how sugar units are strung together into long carbohydrate chains has also pinpointed a promising way to target new medicines against tuberculosis.

23 Jun 2009

Search for prostate cancer biomarkers continues

Collaboration in prostate cancer translational research in Europe is not only vital to sustain the progress achieved in recent years but also to streamline current efforts between researchers and clinicians and avoid duplication or overlaps. This was amongst the goals of the two-day Prostate Cancer Translational Research in Europe (PCTRE) Meeting which opened today in Amsterdam, The Netherlands.

23 Jun 2009

New perspective on the causes, effects and potential treatment of sexual dysfunction

Couples' treatment for sexual problems and other innovative approaches to improving sexual health for men and women are on the agenda of sexual medicine experts.

23 Jun 2009

Cryo-electron tomography shows immature HIV in 3D

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is a precursor of the infectious virus, which can cause AIDS.

23 Jun 2009

Adverts highlight different aspects of health reform debate

A coalition of union and liberal groups began running television ads designed to get "the attention of one particular television viewer: Sen. Kay Hagan," The Greensboro (N.C.) News & Record reports.

22 Jun 2009

Obama, AARP announce agreement to cut prescription drug costs

On Monday, President Barack Obama joined with AARP chief Barry Rand to announce "an agreement among pharmaceutical companies to cut prescription drug costs for seniors - and inject some energy into his efforts at comprehensive health care reform," Politico reports. Obama said the companies' goal is to "to reduce the punishing inflation in health care while improving patient care."

22 Jun 2009

Research shows how obesity sets the stage for diabetes

Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two.

22 Jun 2009