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PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

Two simple biomarkers could differentiate which young women with ER+ breast cancer need chemotherapy

New research from Yale Cancer Center identified that two simple biomarkers, immune cells and estrogen receptor levels, could differentiate which young women with ER+ breast cancer need chemotherapy to improve their survival, and which only need a monthly injection to suppress ovarian function.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Researchers assessed the impact of drug combinations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppression.

14 Nov 2022

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

Researchers compared the waning of vaccine-induced immunity from two and three doses of mRNA COVID-19 Pfizer-BioNTech vaccine BNT162b2 by conducting a repeated serological study to assess the prolonged humoral response.

14 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

Flu cases continue to rise throughout the U.S.

The rate of influenza cases throughout the U.S. continues to rise.

13 Nov 2022

How lessons from the HIV epidemic can help combat COVID-19

Researchers revisit lessons learned from the HIV pandemic in response to COVID-19.

13 Nov 2022

Updated EULAR recommendations on the use of DMARDs for people with RA

Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organizations and other stakeholders to offer an up-to-date and robust analysis on an optimal approach to the application of available treatment options in clinical practice.

11 Nov 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Intranasal (in.) administration has been garnering increasing popularity as a non-invasive approach to deliver drugs directly to the brain. This approach involves the respiratory or olfactory epithelia of the nasal mucosa through which the drugs reach the central nervous system (CNS).

11 Nov 2022

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

In a recent study posted to the medRxiv* server, researchers evaluated non-invasive transcutaneous vagus nerve stimulation [tVNS] as a treatment for long COVID-related chronic fatigue syndrome (CFS).

10 Nov 2022

$3.2 million grant helps to study the benefits of mind-body practices for patients undergoing surgery

Can mind-body practices such as gentle yoga or self-reflection benefit patients undergoing surgery? It's a question that researchers at Wake Forest University School of Medicine are examining with the support of a five-year, $3.2 million grant from the National Cancer Institute

10 Nov 2022

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Researchers investigated the neutralization antibody titers and the efficacy of the humoral and cellular immunities in individuals vaccinated with three COVID-19 vaccines.

10 Nov 2022

Study finds differences in brain structure between boys and girls with binge eating disorders

Conducting the first known comparison of the brains of boys and girls with binge eating disorder, a team of researchers from the Keck School of Medicine of USC found significant differences in brain structure between the sexes.

10 Nov 2022

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

Experts at Duke Health were among a multi-national team involved in treating a fetus for infantile-onset Pompe disease using an enzyme replacement therapy - a first in the world.

9 Nov 2022

First transfusions of lab-grown blood

Two patients in the United Kingdom received two small doses of lab-grown blood samples as part of the RESTORE trial.

9 Nov 2022

Understanding the neurological basis of live social interaction with eye-contact in autism

A hallmark of autism spectrum disorder, ASD, is the reluctance to make eye contact with others in natural conditions.

9 Nov 2022

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

There is a need for new, effective treatments for mental illnesses like depression and anxiety. Researchers are expanding the field's therapeutic toolbox by investigating the antidepressant and anxiolytic properties of drugs such as psilocybin and cannabis.

9 Nov 2022

MHRA grants approval for second Pfizer/Biontech bivalent Covid-19 booster vaccine

Approval has today been granted by the Medicines and Healthcare products Regulatory Agency (MHRA) for a Pfizer/BioNTech 'bivalent' Covid vaccine that targets both the Original strain of SARS-CoV-2 and the Omicron BA.4 and BA.5 sub-variants.

9 Nov 2022

Efficacy News and Research

PALS program effective in ensuring diverse representation in lupus clinical trials

Two simple biomarkers could differentiate which young women with ER+ breast cancer need chemotherapy

Novel drug could help to fight both COVID-19 and cancer

Exploring antiviral drug combinations for SARS-CoV-2 suppression

Long-term humoral response and its determinants following 2- and 3-dose COVID-19 mRNA vaccines

How mRNA vaccines work without an added adjuvant

Flu cases continue to rise throughout the U.S.

How lessons from the HIV epidemic can help combat COVID-19

Updated EULAR recommendations on the use of DMARDs for people with RA

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Study evaluates transcutaneous vagus nerve stimulation as treatment for long COVID-chronic fatigue

$3.2 million grant helps to study the benefits of mind-body practices for patients undergoing surgery

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Study finds differences in brain structure between boys and girls with binge eating disorders

Duke scientists join team involved in the first use of fetal therapy for Pompe disease

First transfusions of lab-grown blood

Understanding the neurological basis of live social interaction with eye-contact in autism

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

MHRA grants approval for second Pfizer/Biontech bivalent Covid-19 booster vaccine

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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