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New peptide molecule offers hope for emphysema

Emphysema is a progressive, debilitating lung disease in which the lung's breathing sacs, or alveoli, enlarge, get thinner, and eventually are destroyed as the cells die off. It can be fatal, and there is currently no cure.

4 Aug 2020

ALKBH5 enzyme shows promising target for cancer immunotherapy

Cancer immunotherapy - a treatment that better enables a patient's own immune system to attack tumors - has shown great potential against some cancers. Yet immunotherapy doesn't work against all tumor types, and many patients who initially respond later develop resistance and relapse.

4 Aug 2020

Study identifies possible therapeutic treatment for COVID-19

Yunjeong Kim and Kyeong-Ok "KC" Chang, virologists in the College of Veterinary Medicine at Kansas State University, have published a study showing a possible therapeutic treatment for COVID-19.

3 Aug 2020

Chlamydiae need a lot of glutamine to multiply in human cells

If chlamydiae want to multiply in a human cell, the first thing they need is a lot of glutamine. Würzburg researchers have clarified how the pathogenic bacteria obtain this substance.

3 Aug 2020

New head lice treatment receives FDA approval

The treatment, Xeglyze, was developed by Hatchtech, an Australian pharmaceutical company and will be commercialized by Dr Reddy's Laboratories.

3 Aug 2020

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on its ability to infect new host cells following its replication and release from infected cells. This pivots on its ability to bind to cell surface receptors like the ACE2 enzyme.

3 Aug 2020

Study sheds light on potential new treatment approach in AML patients

Tyrosine kinases are protein enzymes that have many functions within cells, including cell signaling, growth, and division. Sometimes these enzymes can be overactive, which helps cancer cells survive and multiply.

31 Jul 2020

Study offers new possibilities for developing anti-aging drugs

KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low.

31 Jul 2020

Touchlight, Cancer Research UK and University of Southampton team up to develop DNA cancer vaccine

Cancer Research UK, the University of Southampton and Touchlight Genetics, a London based biotechnology company, today (Wednesday) announce a new clinical development partnership to progress a therapeutic DNA vaccine, TGL-100, into an early phase clinical trial targeting head and neck squamous cell carcinoma.

31 Jul 2020

Discovery could have important implications for brain infections, neurodegenerative diseases

More than 30 million Americans are infected with a brain parasite spread by cats and contaminated meat, but most will never show symptoms.

31 Jul 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

Research shows how Zika virus succeeds in protecting key parts of its genome

To fight viruses, cells can deploy defence enzymes that progressively destroy viral genome strands starting from one of the two strand ends. However, this degradation mechanism is not effective against epidemic viruses such as Zika.

30 Jul 2020

Study explains the mechanisms used by human brain to recognize specific smells

However, this precision only concerns the first "door" for the odors' recognition, namely the nose. But something changes when the information collected and processed by the nose arrives in a more central structure of the brain, called the olfactory cortex.

29 Jul 2020

New study shows the mechanism of brain to recognize specific smells

An Italian-American research conducted by researchers at the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) in Rovereto (Italy) and Harvard University in Boston (Usa) explains for the first time the mechanisms used by our brain to recognize specific smells.

29 Jul 2020

'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

Novel drug candidate offers a major advance in the treatment for diabetes

The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.

28 Jul 2020

TARA Biosystems and VantAI team up to accelerate drug development for cardiac disease

VantAI and TARA Biosystems today announced the launch of a biology-driven, AI-enabled collaboration for accelerated cardiac drug development.

28 Jul 2020

Study shows how aging causes lung regeneration to go awry

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases -- creating more of themselves and producing mature airway cells -- to regenerate lung tissue after an injury.

28 Jul 2020