Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

HDAC inhibitors may help regulate alcoholism-induced anxiety

Epigenetics is the study of changes in organisms caused by modifying gene expression - by alcohol, for example - rather than alteration of the genetic code itself. Recent evidence suggests that alcohol can inhibit activity of an enzyme called histone deacetylase (HDAC) in the amygdala, a brain region that is crucial for storing memories and regulating fear, anxiety, and other emotions.

27 Jun 2016

KIT researchers develop 3D prostate model based on cryogels

A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology are developing a three-dimensional model for prostate cancer research based on cryogels.

25 Jun 2016

NCX1 protein could help prevent progression of heart failure

A protein known to be crucial for maintaining the balance of calcium in cells could prove useful in halting the progression of heart failure.

24 Jun 2016

Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer.

24 Jun 2016

Scientists discover how faulty genetic instructions contribute to development of AML

Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML.

24 Jun 2016

Study reveals surprising diversity in single neuronal transcriptomes of the brain

A team of scientists at The Scripps Research Institute, University of California, San Diego and Illumina, Inc., has completed the first large-scale assessment of single neuronal "transcriptomes."

24 Jun 2016

Researchers develop plasma QC assay for downstream metabolomics applications

Researchers from IBBL and the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have investigated the impact of variations in temperature and delays during blood sample processing on downstream metabolomics applications.

22 Jun 2016

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing.

22 Jun 2016

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Tumors are composed of many subpopulations of cells. A general consensus among scientists is that these subpopulations are due to random mutations. However, Moffitt Cancer Center researchers found that these assumptions may be incorrect.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

Penn researchers help identify unique characteristics of reserve stem cells

Adult stem cells represent a sort of blank clay from which a myriad of different cell and tissue types are molded and as such are of critical importance to health, aging and disease.

16 Jun 2016

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

A paper by Brazilian researchers published in the journal Scientific Reports describes a study showing that a subgroup of olfactory neurons in the nasal cavity express a cellular receptor specializing in the transport of lipid molecules.

14 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

Findings may help explain why rheumatoid arthritis drugs vary in effect

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA.

12 Jun 2016

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

Hepatocellular carcinoma, the most common type of liver cancer, is increasing in incidence in the United States, and infection with the Hepatitis B virus (HBV) causes about 50 percent of cases.

7 Jun 2016

Gene Expression News and Research

Further Reading

HDAC inhibitors may help regulate alcoholism-induced anxiety

KIT researchers develop 3D prostate model based on cryogels

NCX1 protein could help prevent progression of heart failure

Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Scientists discover how faulty genetic instructions contribute to development of AML

Study reveals surprising diversity in single neuronal transcriptomes of the brain

Researchers develop plasma QC assay for downstream metabolomics applications

New study suggests how rod photoreceptors may have originated to give rise to nocturnal mammals

Moffitt researchers develop mathematical model to show differences in subpopulations of tumors

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

E-cigarette use modifies gene expression important for upper airway immune defense

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

Penn researchers help identify unique characteristics of reserve stem cells

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

Study shows similarity between embryonic and reprogrammed stem cells

Findings may help explain why rheumatoid arthritis drugs vary in effect

Carfilzomib therapy shows promise for pre-kidney transplant patients

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

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