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Mitochondrial peptide Humanin linked to neuronal cell survival and regulation of glucose metabolism

Recent studies have shown that the mitochondrial peptide Humanin (HN) protects against neuronal cell death such as happens in Alzheimer's disease.

22 Apr 2009

Scientists make significant strides in identifying cause of bacterial infections

Several bacterial pathogens use toxins to manipulate human host cells, ultimately disturbing cellular signal transduction.

22 Apr 2009

FDA gives 'go ahead' for phase II clinical trials of Bryostatin for the treatment of Alzheimer's disease

The Food and Drug Administration (FDA) has given the Blanchette Rockefeller Neurosciences Institute (BRNI) the go-ahead to conduct Phase II clinical trials of Bryostatin for the treatment of Alzheimer's disease patients.

22 Apr 2009

Genes influence impulsivity, which may then contribute to risk for developing alcoholism

Numerous studies have shown that highly impulsive behavior - defined as the tendency to choose small, immediate rewards over larger, delayed rewards - is more prevalent in drug addicts and alcoholics compared to individuals without addictions.

22 Apr 2009

Double-lung transplants work better than single for long-term survival

Having both lungs replaced instead of just one is the single most important feature determining who lives longest after having a lung transplant, more than doubling an organ recipient's chances of extending their life by over a decade, a study by a team of transplant surgeons at Johns Hopkins shows.

22 Apr 2009

New applications for proton pump inhibitors

In a new study, published in the May issue of Elsevier's Experimental Neurology (www.elsevier.com/locate/yexnr), scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug.

22 Apr 2009

Developmental drug protects cells from the damaging effects of radiation exposure

A drug currently under development at the University of Pittsburgh School of Medicine protects cells from the damaging effects of radiation exposure, a new study suggests.

22 Apr 2009

The influence of risk-taking behaviors on the transition into marriage

A national study of data collected over 12 years finds that delinquent teens marry earlier than their peers, while substance-abusing teens -- especially girls who abuse marijuana -- marry later than peers, if at all.

22 Apr 2009

New Dengue virus discovery could lead to development of anti-dengue drugs

Doctors have no specific drugs to treat dengue fever, a viral illness spread by mosquitoes that sickens 50 million to 100 million people worldwide each year. Instead, the only treatments they can recommend for this painful and sometimes fatal illness (20,000 deaths globally each year) are fluids, rest and non-aspirin pain and fever reducers.

22 Apr 2009

PDAs, more education help doctors follow cholesterol treatment guidelines

A new study by researchers at Wake Forest University School of Medicine suggests that patients with high cholesterol receive better care when physicians use a variety of tools to learn and apply a clinical practice guideline for treating the condition.

22 Apr 2009

Discovery of two important molecules that underlie the pathology of lupus, particularly kidney disease

Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study.

22 Apr 2009

Retooled chemotherapy agents for drug delivery may increase effectiveness

Researchers may have found a way to combine imaging with chemotherapy in a single agent for the treatment of prostate cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009

22 Apr 2009

Scientists suggest a mechanism for how lithium works in bipolar treatment

Lithium has been established for more than 50 years as one of the most effective treatments for bipolar mood disorder.

22 Apr 2009

Combination of two chemotherapy drugs shows promise against recurrent gynecologic cancers

Recurrent and metastatic endometrial and ovarian cancers can be notoriously difficult to treat: They have spread to other organs and typically have developed resistance to chemotherapy; and patients already heavily treated with chemotherapy may not be able to endure more chemo.

22 Apr 2009

How cells control the great divide

A scientist whose work is key to understanding how cancer cells divide and spread in the body is to present advances in his latest research at a public forum to be held at the University of Leicester.

22 Apr 2009

Discovery of agents that speed up destruction of amyloid beta proteins

Taking a new approach to the treatment and prevention of Alzheimer's disease, a research team led by investigators at the Mayo Clinic campus in Florida has shown that druglike compounds can speed up destruction of the amyloid beta (A-beta) proteins that form plaque in the brains of patients with the disorder.

22 Apr 2009

Drugs News and Research

Mitochondrial peptide Humanin linked to neuronal cell survival and regulation of glucose metabolism

Scientists make significant strides in identifying cause of bacterial infections

FDA gives 'go ahead' for phase II clinical trials of Bryostatin for the treatment of Alzheimer's disease

Genes influence impulsivity, which may then contribute to risk for developing alcoholism

Double-lung transplants work better than single for long-term survival

New applications for proton pump inhibitors

Developmental drug protects cells from the damaging effects of radiation exposure

The influence of risk-taking behaviors on the transition into marriage

New Dengue virus discovery could lead to development of anti-dengue drugs

PDAs, more education help doctors follow cholesterol treatment guidelines

Discovery of two important molecules that underlie the pathology of lupus, particularly kidney disease

Retooled chemotherapy agents for drug delivery may increase effectiveness

Scientists suggest a mechanism for how lithium works in bipolar treatment

Combination of two chemotherapy drugs shows promise against recurrent gynecologic cancers

How cells control the great divide

Discovery of agents that speed up destruction of amyloid beta proteins

Acetylsalicylic acid plus clopidogrel reduces heart attack risk in patients with acute ischaemia

Early treatment for hepatitis C offers a good chance of a cure

The effect of tea polyphenols on paracetamol-induced hepatotoxicity

New drug to target tumor cells and blood vessels

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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